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Applications of Mass Spectrometry in Microbiology From Strain Characterization to Rapid Screening for Antibiotic Resistance【電子書籍】

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<p>In the last quarter century, advances in mass spectrometry (MS) have been at the forefront of efforts to map complex biological systems including the human metabolome, proteome, and microbiome. All of these developments have allowed MS to become a well-established molecular level technology for microorganism characterization. MS has demonstrated its considerable advantage as a rapid, accurate, and cost-effective method for microorganism identification, compared to conventional phenotypic techniques. In the last several years, applications of MS for microorganism characterization in research, clinical microbiology, counter-bioterrorism, food safety, and environmental monitoring have been documented in thousands of publications. Regulatory bodies in Europe, the US, and elsewhere have approved MS-based assays for infectious disease diagnostics. As of mid-2015, more than 3300 commercial MS systems for microorganism identification have been deployed worldwide in hospitals and clinical labs.</p> <p>While previous work has covered broader approaches in using MS to characterize microorganisms at the species level or above, this book focuses on strain-level and subtyping applications. In twelve individual chapters, innovators, leaders and practitioners in the field from around the world have contributed to a comprehensive overview of current and next-generation approaches for MS-based microbial characterization at the subspecies and strain levels. Chapters include up-to-date reference lists as well as web-links to databases, recommended software, and other useful tools.</p> <p>The emergence of new, antibiotic-resistant strains of human or animal pathogens is of extraordinary concern not only to the scientific and medical communities, but to the general public as well. Developments of novel MS-based assays for rapid identification of strains of antibiotic-resistant microorganisms are reviewed in the book as well. Microbiologists, bioanalytical scientists, infectious disease specialists, clinical laboratory and public health practitioners as well as researchers in universities, hospitals, government labs, and the pharmaceutical and biotechnology industries will find this book to be a timely and valuable resource.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 12,154円

Uterine Cancer Screening, Diagnosis, and Treatment【電子書籍】

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<p>For the Editors, the task of writing a Preface is most satisfying. It represents the completion of the book and a moment of reflection on whether the whole is more than the sum of all the parts. And also, one must reflect on how this book is likely to be utilized in this era of rapid communications. The Editors first met in May 2003 at a stimulating Italian symposium on endometrial cancer (organizers Drs. Luigi Frigerio, Roberto Grassi and Andrea Lissoni, with participation of the deans of Italian Gynecologic Oncology, Ugo Bianchi and Constantino Mangioni) that took place at Bergamo and Caravaggio. The impressive gains in biology and clinical trials were further discussed by the two editors and others that are co-authors in this venture on this side of the Atlantic at a 2004 Educational Session at the American Society of Clinical Oncology (ASCO). The pace of progress in various aspects of management of uterine cancer was no- worthy, not only was tumor biology fueling novel hypotheses such as questioning the mesenchymal origin of carcinosarcomas, but knowledge of molecular pathways was beginning to be applied as prognostic and as predictive factors portending benefit from systemic therapies. Surgical staging and sensitive imaging provided the underpinning for refining our treatment algorithms. Finally, a role for che- therapy had finally become established, principally through phase III studies c- paring chemotherapy to radiation in mostly locally advanced stages III and IV that had undergone resection.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 24,309円

Seeking Sickness Medical Screening and the Misguided Hunt for Disease【電子書籍】[ Alan Cassels ]

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<p><strong>"Alan Cassels strips layers of expectation, hype, jargon, false-starts, and conflicts of interest off the medical screening mantra." ーNortin M. Hadler, author of <em>Worried Sick</em></strong><br /> Why wouldn't you want to be screened to see if you're at risk for cancer, heart disease, or another potentially lethal condition? After all, better safe than sorry. Right?<br /> Not so fast, says Alan Cassels. His <em>Seeking Sickness</em> takes us inside the world of medical screening, where well-meaning practitioners and a profit-motivated industry offer to save our lives by exploiting our fears. He writes that promoters of screening overpromise on its benefits and downplay its harms, which can range from the merely annoying to the life threatening. If you're facing a screening test for breast or prostate cancer, high cholesterol, or low testosterone, someone is about to turn you into a patient. You need to ask yourself one simple question: <em>Am I ready for all the things that could go wrong?</em><br /> "With engaging clarity backed by academic rigor, Cassels discusses a variety of popular investigational procedures . . . an excellent way to start the important process of self-education." ー <em>Quill & Quire</em><br /> "Smartly written and very readable." ーBrian Goldman, MD, author of <em>The Secret Language of Doctors</em><br /> "Cassels tackles this touchy topic, looking at it test by test. His overarching message is that modern medicine has 'overpromised' with claims that screening will save our lives. He contends that with the lack of hard evidence on benefits, the evidence of harm from by such screening, as well as the multi-billion dollar interests at stake, we should approach this kind of screening with great <em>pre</em>caution." ー <em>Canadian Women's Health Network</em></p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 1,760円

Screening and Risk Reduction Strategies for Breast Cancer Imaging Modality and Risk-Reduction Approaches【電子書籍】

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<p>This book provides readers with the most up-to-date practical information on breast cancer screening. Since breast cancers are highly heterogeneous, time to clinical onset from the initial carcinogenesis differs diversely between cancers. Pathological germline variants and driver mutations cause a high lifetime risk of breast cancer. The lifetime risks are various according to what genes are pathologically dysfunctional. Integrated omics and imaging technologies have established varying tumour characteristics. Thus, this book suggests that a more individualised scheme is required to improve breast cancer screening.</p> <p>A key aim is to demonstrate how multiple diagnostic imaging modalities such as mammography, ultrasonography, MRI, PET and dbPET improve breast cancer screening accuracy. Mammography screening alone may have a limited impact on breast cancer risk prediction. These issues are crucial to discuss. Clinical experts recommend that new modalities be incorporated for women with dense breasts, like ultrasonography, dynamic mammography, MRI and maybe breast-dedicated PET. Topics on these modalities are going to be summarized in this book. An in-depth review of these modalities is summarised in this book. In addition, new diagnostic modalities, including risk assessment tools, multi-cancer early detection tests using liquid biopsy, the role of protein biomarkers in breast cancer risk screening, challenges, and hopes for future advances, are also covered in this book.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 13,369円

Personalized Drug Screening for Functional Tumor Profiling【電子書籍】[ Victoria El-Khoury ]

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<p>Despite considerable advances in our understanding of the biology that underlies tumor development and progression of cancer and the rapidly evolving field of personalized medicine, cancer is still one of the deadliest diseases. Many cancer patients have benefited from the survival improvements observed with targeted therapies but only a small subset of patients receiving targeted drugs experience an objective response. Because cancer is a complex and heterogeneous disease, the search for effective cancer treatments will need to address not only patient-specific molecular defects but also aspects of the tumor microenvironment. The functional tumor profiling directly measures the cellular phenotype, in particular tumor growth, in response to drugs using patient-derived tumor models and might be the next step toward precision oncology. In this Element, the authors discuss the personalized drug screening as a novel patient stratification strategy for the determination of individualized treatment choices in oncology.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 3,051円

Screening the Author The Literary Biopic【電子書籍】[ Hila Shachar ]

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<p>This book is the first comprehensive analysis of the contemporary representation of the author on screen. It does this through two main approaches: by looking at how biographies of well-known authors in Western culture have been adapted onto the film and television screen; and by examining the wider preoccupation with the idea of what the ‘author persona’ means in broader economic, cultural, industrial, and ideological terms. Drawing from current debates about the uses of the heritage industry and conventions of the Hollywood biopic and celebrity culture, this book re-frames the analysis of the author on screen in contemporary culture and theorises it under its own unique genre: the ‘literary biopic’. With case studies including adaptations of the biographies and cultural personas of William Shakespeare, Jane Austen, Oscar Wilde, Sylvia Plath, Virginia Woolf, and Allen Ginsbergーto name a few?this book examines how and why the author continues to be a prominent screen and cultural preoccupation.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 10,331円

European Cinema after the Wall Screening East-West Mobility【電子書籍】

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<p>Since the fall of the Berlin Wall in 1989, transnational European cinema has risen, not only in terms of production but also in terms of a growing focus on multiethnic themes within the European context. This shift from national to trans-European filmmaking has been profoundly influenced by such historical developments as the collapse of the Iron Curtain and the subsequent ongoing enlargement of the European Union.</p> <p>In European Cinema after the Wall: Screening East?West Mobility, Leen Engelen and Kris Van Heuckelom have brought together essays that critically examine representations of post-1989 migration from the former Eastern Bloc to Western Europe, uncovering an array of common tropes and narrative devices that characterize the influences and portrayals of immigration.</p> <p>Featuring essays by contributors from backgrounds as divergent as film studies, Slavic and Russian studies, comparative literature, sociology, contemporary history, and communication and media studies, this volume will appeal to scholars of film, European history, and those interested in the impact of migration, diaspora, and the global flow of cinematic culture.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 14,205円

Private Screening【電子書籍】[ Richard North Patterson ]

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<p>The nation is stunned silent when presidential hopeful James Kilcannon is shot dead point blank, while sharing the stage at a benefit concert with his rock star girlfriend Stacy Tarrant. Fiercely independent attorney Tony Lord defends the assassin in a sensational trial that erupts in to the media event of the decade. But the most shocking gambit ever witnessed in the history of television has yet to unfold. As America watches, a mysterious and ruthless figure known only as Phoenix takes to the airwaves in the ultimate act of high-tech terror. Holding the wife of a wealthy newspaper mogul and Stacy's manager hostage, Phoenix mounts a televised trial of his own - in which Stacy Tarrant and Tony Lord are the helpless defendants, millions of viewers are jurors, and - unless his chilling demands are met - Phoenix is the unstoppable executioner. . .</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 1,212円

Advances in Cancer Screening【電子書籍】

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<p>Screening for cancer is an important focus of cancer control. Yet screening, as it involves administering a test to large segments of the population deemed to be at risk for the disease of interest, is potentially a major consumer of scarce health care resources. In addition, the benefits sought from cancer screening, particularly reduction in mortality from the disease, are not always realized, either for biological or organizational reasons. Thus, the paradigm that `early detection must always be beneficial', taught to health care professionals, and publicized widely through the media to the public, has been challenged in the last two decades for a number of cancer sites. It is the purpose of <em>Advances in Cancer Screening</em> to determine the extent to which the requirements for the introduction of population-based screening programs have been met, as a result of extensive research on screening during the last two decades, with a major concentration on findings from the recent decade.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 24,309円

Early Cancer Detection in Primary Care Are You Aware of New Blood-Based Multi-Cancer Screening Tools【電子書籍】[ Lincoln Nadauld, MD, PhD ]

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<p>Despite significant advances in therapy, cancer continues to impose enormous medical, economic, and social burdens. Each year in the United States, approximately 1700 people die from cancer each day, making it the leading cause of mortality in people younger than 80 years old. The costs of treating cancer, including drugs, hospitalization, and ambulatory care, exceed $157 billion annually. Indirect costs, including lost productivity and absenteeism, add nearly another $100 billion to the tally. Early detection is an essential step in reducing the burdens of cancer. Identifying cancer at its earliest stages improves outcomes by allowing therapy to begin sooner, decreasing treatment costs and complexity, reducing morbidity and mortality, and improving quality of life. Liquid biopsy?based multi-cancer early detection (MCED) tests have been developed to support population-based screening of asymptomatic individuals for dozens of cancer types. This multimedia educational activity has been designed to help primary care cliniciansーthe most important facilitators of preventive healthcare and cancer screeningーunderstand the technology behind MCED tests, interpret data from clinical trials, engage in shared decision-making to determine which patients should be tested, and plan for follow-up examinations in response to a positive test.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 50円

【中古】【輸入品・未使用】Kinase Screening and Profiling: Methods and Protocols (Methods in Molecular Biology%カンマ% 1360)

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【中古】【輸入品・未使用】Kinase Screening and Profiling: Methods and Protocols (Methods in Molecular Biology%カンマ% 1360)【メーカー名】Humana【メーカー型番】【ブランド名】Humana【商品説明】Kinase Screening and Profiling: Methods and Protocols (Methods in Molecular Biology%カンマ% 1360)当店では初期不良に限り、商品到着から7日間は返品を 受付けております。こちらは海外販売用に買取り致しました未使用品です。買取り致しました為、中古扱いとしております。他モールとの併売品の為、完売の際はご連絡致しますのでご了承下さい。速やかにご返金させて頂きます。ご注文からお届けまで1、ご注文⇒ご注文は24時間受け付けております。2、注文確認⇒ご注文後、当店から注文確認メールを送信します。3、配送⇒当店海外倉庫から取り寄せの場合は10〜30日程度でのお届けとなります。国内到着後、発送の際に通知にてご連絡致します。国内倉庫からの場合は3〜7日でのお届けとなります。 ※離島、北海道、九州、沖縄は遅れる場合がございます。予めご了承下さい。お電話でのお問合せは少人数で運営の為受け付けておりませんので、メールにてお問合せお願い致します。営業時間 月〜金 10:00〜17:00お客様都合によるご注文後のキャンセル・返品はお受けしておりませんのでご了承下さい。 42,091円

Screening the Public Sphere Media and Democracy in India【電子書籍】[ Saima Saeed ]

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<p>For centuries, democracy and development have steered the imagination of governments, citizens, intelligentsia and policymakers alike. Democracy without free media is a contradiction, while development without democracy is futile. Highlighting the power and significance of contemporary media, this book <em>deconstructs</em> news and news-making on Indian television. In exploring the concepts of ‘sense-making’ and ‘meaning-generation’, it examines how news and the dissemination of information and opinion influence the public sphere, participatory democracy, citizenship and civil society. Providing an original interpretation of the paradigmatic shifts in news content and newsroom practices, this book focuses on changing ownership patterns, increasing ‘entertainmentalization’ of news and the resultant ‘developmental reportage deficit’. At the same time, it confronts the uneasy and critical consequences of commercialization and rising sensationalism in news media. Finally, it discusses the role of Public Service Broadcasting, journalistic ethics, objectivity, and the politics of language and ideology in the media today, pointing to the need for greater diversity of content on the one hand and an emphasis on public interest in media policy-making, on the other.</p> <p>Drawing upon comprehensive empirical data, the <em>democracy?media?development</em> relationship is demonstrated through critical analyses of the media’s coverage of recent news events. This includes exhaustive content examination of news programmes on all major news channels of India, surveys with media experts and news professionals by way of questionnaires, and interviews with the audience to gauge the impact of media content on their understanding of social, political and economic issues. This volume will be especially useful to those in journalism, media and communication studies, as also to students of political science, sociology and economics.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 11,772円

Prevention, Screening and Treatments for Obstructive Sleep Apnea: Beyond PAP, An Issue of Sleep Medicine Clinics【電子書籍】[ Song Tar Toh, MMED, FAMS, Mmed, MRCSEd, MBBS ]

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<p>This issue of Sleep Medicine Clinics, edited by Song Tar Toh in collaboration with Consulting Editor, Teofilo Lee-Chiong, is devoted to the Preventing, Screening, and Treatments for Obstructive Sleep Apnea, beyond Positive Airway Pressure (PAP). Topics covered in this issue include: Prevention and Screening of Obstructive Sleep Apnea (OSA); Anatomical and Physiologic Considerations in Surgical Treatment for OSA; Medical and Surgical Options for Weight Management in OSA; Positional Therapy for OSA; Oral Appliances in Adults and Pediatrics; Myofunctional Therapy for OSA; Drug-induced Sleep Endoscopy in Treatment Options Selection; Establishing a Patent Nasal Passage in OSA; Palatal Surgery: From Ablation to Reconstruction; Volumetric Tongue Reduction Surgery in Clinical Practice; Transoral Robotic Surgery for OSA; Genioglossus Advancement and Hyoid Surgery; Maxillomandibular Rotational Advancement: Airway, Aesthetics, and Angle Considerations;</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 9,782円

Screening the Single Euploid Embryo Molecular Genetics in Reproductive Medicine【電子書籍】

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<p>Intended for readers with a background in fertility medicine as well as those less familiar with IVF, this comprehensive work presents an update on preimplantation genetic testing to enable single embryo transfer (SET). An international cast of contributors explains the treatment sequenceーfrom ovulation induction to luteal supportーaiming to transfer only one euploid embryo. Applications of molecular techniques for gamete and embryo assessment are fully detailed, with a focus on the strengths and limitations of each. In addition, expert commentary is shared across a range of regulatory challenges associated with embryo screening and cryopreservation. As access to advanced reproductive technology increases against a sharper background of healthcare reform, clinicians, economists, bioethicists and legislators alike will find this new volume relevant and highly accessible.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 12,154円

Surgical Treatment of Bronchial Carcinoma Screening Methods, Early and Late Results【電子書籍】[ J. Hasse ]

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<p>If a consecutive series of patients with lung cancer is followed up until the decision is made about therapy, it emerges that the role of surgery is quite small. Only a very limited proportion will ultimate ly qualify for rationally conceived surgical therapy; most patients are inoperable. In a series of 397 patients investigated at our hospi tal, 78% were inoperable on the basis of preoperative evaluation and a further 3% proved nonresectable at thoracotomy; therefore, only 19% were suitable for resection. On the other hand, surgery is still thought to offer the best, if not the only realistic chance of cure. The question "operable or not?" is therefore of vital importance for the individual patient. The answer to this crucial question must be based on valid guidelines for pa tient selection and preoperative evaluation, and it should be clearly defined what extent of resection is necessary in order to realize any curative intention. In 1972 a thorough analysis of the literature revealed that re section of bronchial carcinoma - although 40 years old - was being undertaken with very variable indications. There was hardly any systematic staging, and assessment of results was hampered by the fact that most communications in the literature were based on retrospective analysis.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 12,154円

Prostate Cancer Screening Second Edition【電子書籍】

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<p>More than one in six men will develop prostate cancer in their lifetime. In recent years there has been an explosion of information regarding PSA screening and biomarkers for the disease. In Prostate Cancer Screening, Second Edition, the world’s leading experts on prostate cancer detection update the first edition with the latest findings. The book incorporates a series of thoughtful and cutting-edge works from the world’s experts in prostate cancer screening, ranging from the current status quo of prostate cancer screening across the globe to consensus on optimal utilization of the traditional PSA and DRE tests, to cutting-edge research in new biomarkers, biomeasures, and extended risk algorithms for prostate cancer. An additional chapter covers family-based linkage analysis as well as possible pitfalls in prostate cancer biomarker evaluation studies. Timely and authoritative, Prostate Cancer Screening, Second Edition, is an essential text for urologists, oncologists and family physicians, as well as researchers in the biomarker industry who seek methods to better develop and support markers and measures of prostate cancer.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 24,309円

S3-Leitlinie Screening, Diagnose und Behandlung alkoholbezogener St?rungen【電子書籍】

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<p>Das Buch liefert ? unter Einbeziehung der Erkenntnisse aus der aktuellen Forschung ? detaillierte Leitlinien zur Fr?herkennung von Alkoholproblemen und zur optimalen Behandlung von betroffenen Personen. F?r die 2020 aktualisierte Auflage wurden alle Kapitel hinsichtlich neuer Forschungsergebnisse und aktueller Literatur ?berpr?ft und die Empfehlungen ?berarbeitet.</p> <p>Die Empfehlungen richten sich an ?rztInnen und PsychologInnen in Klinik und Praxis, an Mitarbeitende in Reha-Einrichtungen und Beratungsstellen, sowie an Betroffene und deren Angeh?rige.</p> <p>Die Leitlinie bildet die Grundlage f?r eine evidenzbasierte Behandlung und soll einen leichteren Zugang zum umfangreichen Hilfesystem erm?glichen.</p> <p>Die wichtigsten Inhalte auf einen Blick:</p> <ul> <li>Empfehlungen zu Screening, Case Finding und Diagnostik von alkoholbezogenen St?rungen</li> <li>Behandlungsempfehlungen f?r Personen mit alkoholbezogenen St?rungen in im akuten und postakuten Setting</li> <li>Empfehlungen f?r verschiedene Gruppen der Gesellschaft</li> <li>Besonderer Fokus auf die deutsche Versorgungslandschaft</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 5,906円

Screening Soviet Nationalities Kulturfilms from the Far North to Central Asia【電子書籍】[ Oksana Sarkisova ]

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<p>Filmmakers in the early decades of the Soviet Union sought to create a cinematic map of the new state by portraying its land and peoples on screen. Such films created blueprints of the Soviet domain's scenic, cultural and ethnographic perimeters and brought together - in many ways disparate - nations under one umbrella. Categorised as kulturfilms, they served as experimental grounds for developing the cinematic formulae of a multiethnic, multinational Soviet identity. Screening Soviet Nationalities examines the non-fictional representations of Soviet borderlands from the Far North to the Northern Caucasus and Central Asia between 1925-1940. Beginning with Dziga Vertov and his vision of the Soviet space as a unified, multinational mosaic, Oksana Sarkisova rediscovers films by Vladimir Erofeev, Vladimir Shneiderov, Alexander Litvinov, Mikhail Slutskii, Amo Bek-Nazarov, Mikhail Kalatozov, Roman Karmen and other filmmakers who helped construct an image of Soviet ethnic diversity and left behind a lasting visual legacy.The book contributes to our understanding of changing ethnographic conventions of representation, looks at studies of diversity despite the homogenising ambitions of the Soviet project, and reexamines methods of blending reality and fiction as part of both ideological and educational agendas.<br /> Using a wealth of unexplored archival evidence from the Russian State Documentary Film and Photo Archive (RGAKFD) as well as the Gosfilmofond state film archive, Sarkisova examines constructions of exoticism, backwardness and Soviet-driven modernity through these remarkable and underexplored historical travelogues.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 5,701円

Anticancer Drug Development Guide Preclinical Screening, Clinical Trials, and Approval【電子書籍】

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<p>This unique volume traces the critically important pathway by which a "molecule" becomes an "anticancer agent. " The recognition following World War I that the administration of toxic chemicals such as nitrogen mustards in a controlled manner could shrink malignant tumor masses for relatively substantial periods of time gave great impetus to the search for molecules that would be lethal to specific cancer cells. Weare still actively engaged in that search today. The question is how to discover these "anticancer" molecules. Anticancer Drug Development Guide: Preclinical Screening, Clinical Trials, and Approval, Second Edition describes the evolution to the present of preclinical screening methods. The National Cancer Institute's high-throughput, in vitro disease-specific screen with 60 or more human tumor cell lines is used to search for molecules with novel mechanisms of action or activity against specific phenotypes. The Human Tumor Colony-Forming Assay (HTCA) uses fresh tumor biopsies as sources of cells that more nearly resemble the human disease. There is no doubt that the greatest successes of traditional chemotherapy have been in the leukemias and lymphomas. Since the earliest widely used in vivo drug screening models were the murine L 1210 and P388 leukemias, the community came to assume that these murine tumor models were appropriate to the discovery of "antileukemia" agents, but that other tumor models would be needed to discover drugs active against solid tumors.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 18,231円

敗戦とハリウッド 占領下日本の文化再建 SCREENING ENLIGHTENMENT/北村洋【3000円以上送料無料】

bookfan 1号店 楽天市場店
著者北村洋(著)出版社名古屋大学出版会発売日2014年08月ISBN9784815807757ページ数220,83Pキーワードはいせんとはりうつどせんりようかにほんのぶんか ハイセントハリウツドセンリヨウカニホンノブンカ きたむら ひろし キタムラ ヒロシ9784815807757内容紹介アメリカ映画を抱きしめて??。占領政策の一環としてハリウッド映画を利用したGHQと、その到来を歓迎して映画館へと押し寄せた日本人。両者の関係を多面的な交渉のプロセスと捉え、検閲・配給・宣伝をめぐる様々な試行錯誤から、ファン文化の形成まで、熱狂と葛藤に満ちた占領の文化史を描き出す。※本データはこの商品が発売された時点の情報です。目次第1章 戦前の日本市場での挑戦/第2章 コーポラティズムの再生—ハリウッド・戦争・占領/第3章 闘争の空間—占領期の検閲と日本映画/第4章 ハリウッド対占領/第5章 文化の泉—ハリウッドの配給と宣伝について/第6章 文化の興行—映画館とアメリカ映画の上映について/第7章 文化人と「啓蒙」への渇望/第8章 『映画の友』とアメリカ映画ファン文化の形成 5,280円

High-Throughput Screening Methods in Toxicity Testing【電子書籍】

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<p><strong>Explores the benefits and limitations of the latest high-throughput screening methods</strong></p> <p>With its expert coverage of high-throughput <em>in vitro</em> screening methods for toxicity testing, this book makes it possible for researchers to accelerate and streamline the evaluation and risk assessment of chemicals and drugs for toxicity. Moreover, it enables them to comply with the latest standards set forth by the U.S. National Research Council's "Toxicity Testing in the 21st Century: A Vision and Strategy" and the E.U.'s REACH legislation. Readers will discover a variety of state-of-the-science, high-throughput screening methods presented by a group of leading authorities in toxicology and toxicity testing.</p> <p><em>High-Throughput Screening Methods in Toxicity Testing</em> is divided into five parts:</p> <ul> <li>General aspects, including predicting the toxicity potential of chemicals and drugs via high-throughput bioactivity profiling</li> <li>Assessing different cytotoxicity endpoints</li> <li>Assessing DNA damage and carcinogenesis</li> <li>Assessing reproductive toxicity, cardiotoxicity, and haematotoxicity</li> <li>Assessing drug metabolism and receptor-related toxicity</li> </ul> <p>Each chapter describes method principles and includes detailed information about data generation, data analysis, and applications in risk assessment. The authors not only enumerate the advantages of each high-throughput method over comparable conventional methods, but also point out the high-throughput method's limitations and potential pitfalls. In addition, the authors describe current research efforts to make high-throughput toxicity screening even more cost effective and streamlined.</p> <p>Throughout the book, readers will find plenty of figures and illustrations to help them understand and perform the latest high-throughput toxicity screening methods.</p> <p>This book is ideal for toxicologists and other researchers who need to implement high-throughput screening methods for toxicity testing in their laboratories as well as for researchers who need to evaluate the data generated by these methods.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 21,862円

Statistical Methods for Dynamic Disease Screening and Spatio-Temporal Disease Surveillance【電子書籍】[ Peihua Qiu ]

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<p>Disease screening and disease surveillance (DSDS) constitute two critical areas in public health, each presenting distinctive challenges primarily due to their sequential decision-making nature and complex data structures. <strong>Statistical Methods for Dynamic Disease Screening and Spatio-Temporal Disease Surveillance</strong> explores numerous recent analytic methodologies that enhance traditional techniques. The author, a prominent researcher specializing in innovative sequential decision-making techniques, demonstrates how these novel methods effectively address the challenges of DSDS.</p> <p>After a concise introduction that lays the groundwork for comprehending the challenges inherent in DSDS, the book delves into fundamental statistical concepts and methods relevant to DSDS. This includes exploration of statistical process control (SPC) charts specifically crafted for sequential decision-making purposes. The subsequent chapters systematically outline recent advancements in dynamic screening system (DySS) methods, fine-tuned for effective disease screening. Additionally, the text covers both traditional and contemporary analytic methods for disease surveillance. It further introduces two recently developed R packages designed for implementing DySS methods and spatio-temporal disease surveillance techniques pioneered by the author's research team.</p> <p><strong>Features</strong></p> <p><strong>? Presents Recent Analytic Methods for DSDS:</strong> The book introduces analytic methods for DSDS based on SPC charts. These methods effectively utilize all historical data, accommodating the complex data structure inherent in sequential decision-making processes.</p> <p>? <strong>Introduces Recent R Packages:</strong> Two recent R packages, <strong>DySS</strong> and <strong>SpTe2M</strong>, are introduced. The book not only presents these packages but also demonstrates key DSDS methods using them.</p> <p>? <strong>Examines Recent Research Results:</strong> The text delves into the latest research findings across various domains, including dynamic disease screening, nonparametric spatio-temporal data modeling and monitoring, and spatio-temporal disease surveillance.</p> <p>? <strong>Accessible Description of Methods:</strong> Major methods are described in a manner accessible to individuals without advanced knowledge in mathematics and statistics. The goal is to facilitate a clear understanding of ideas and easy implementation.</p> <p>? <strong>Real-Data Examples:</strong> To aid comprehension, the book provides several real-data examples illustrating key concepts and methods.</p> <p>? <strong>Hands-on Exercises:</strong> Each chapter includes exercises to encourage hands-on practice, allowing readers to engage directly with the presented methods.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 12,269円

Screening the Golden Ages of the Classical Tradition【電子書籍】

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画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 4,917円

Differenzialdiagnostik in der Physiotherapie - Screening, Pathologie, Red Flags【電子書籍】

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<p>Vom Leitsymptom zur richtigen Diagnose ? vom Krankheitsbild zur richtigen TherapieDieses Buch bietet Ihnen: - fundierte Orientierung zur klinischen Urteilsfindung - eine F?lle an Informationen, um Symptome, Erkrankungen und "Red Flags" zu erkennen - Hilfen, um anhand des Red-Flag-Screenings ggf. ?ber eine weitere medizinische Abkl?rung zu entscheiden - einen strukturierten, didaktischen Aufbau, viele ?bersichtstabellen und zahlreiche Fallbeispiele, die Ihnen die Inhalte einpr?gsam vermittelnDas Buch bietet Ihnen eine Vielzahl an Leitsymptomen und Pathologien und gliedert sich in die Bereiche Bewegungsapparat, Nervensystem, Atmung, Herz/Kreislauf, Blut und Abwehr, Hormon- und Immunsystem, Gastrointestinaltrakt, Haut, Urogenitalsystem und Psyche.Erg?nzend werden Syndromale Erkrankungen, Notf?lle sowie besondere Gruppen von Patienten (Sportler, Musiker, Kinder) vorgestellt.Die Kapitel Bildgebung und Pharmakologie bieten Ihnen wertvolle Zusatzinformationen.Seit Beginn der Akademisierung der Physiotherapie vor ca. 20 Jahren wird eine st?rkere Selbstst?ndigkeit der Physiotherapeutinnen und -therapeuten gefordert. Die Zusatzausbildung "Sektoraler Heilpraktiker ? Physiotherapie" erm?glicht inzwischen das Arbeiten im Erstkontakt ohne ?rztliche Verordnung. Aber auch alle anderen Therapierenden sollten in der Lage sein, Symptome zu erkennen ("Red Flags"), die nicht vom muskuloskelettalen oder neuromuskul?ren System stammen.Ein Grundlagenwerk, das Sicherheit f?r die Differenzialdiagnostik in der Physiotherapie gibt!Das Buch eignet sich f?r: - Physiotherapeut*innen in Ausbildung, Studium und Praxis</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 7,840円

洋書 Routledge Paperback, Adoptive and Foster Parent Screening

Glomarket
*** We ship internationally, so do not use a package forwarding service. We cannot ship to a package forwarding company address because of the Japanese customs regulation. If it is shipped and customs office does not let the package go, we do not make a refund. 【注意事項】 *** 特に注意してください。 *** ・個人ではない法人・団体名義での購入はできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 ・お名前にカタカナが入っている場合法人である可能性が高いため当店システムから自動保留します。カタカナで記載が必要な場合はカタカナ変わりローマ字で記載してください。 ・お名前またはご住所が法人・団体名義(XX株式会社等)、商店名などを含めている場合、または電話番号が個人のものではない場合、税関から法人名義でみなされますのでご注意ください。 ・転送サービス会社への発送もできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 *** ・注文後品切れや価格変動でキャンセルされる場合がございますので予めご了承願います。 ・当店でご購入された商品は、原則として、「個人輸入」としての取り扱いになり、すべてニュージャージからお客様のもとへ直送されます。 ・ご注文後、30営業日以内(通常2~3週間)に配送手続きをいたします。配送作業完了後、2週間程度でのお届けとなります。 ・まれに商品入荷状況や国際情勢、運送、通関事情により、お届けが2ヶ月までかかる場合がありますのでお急ぎの場合は注文をお控えください。 ・個人輸入される商品は、すべてご注文者自身の「個人使用・個人消費」が前提となりますので、ご注文された商品を第三者へ譲渡・転売することは法律で禁止されております。 ・関税・消費税が課税される場合があります。詳細はこちらをご確認下さい。PC販売説明文 14,697円

Screening Tech Candidates A Complete Guide - 2019 Edition【電子書籍】[ Gerardus Blokdyk ]

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<p>How do you plan on providing proper recognition and disclosure of supporting companies???? How will success or failure be measured? What is the output? Can you measure the return on analysis? How long will it take to change?</p> <p>This powerful Screening Tech Candidates self-assessment will make you the reliable Screening Tech Candidates domain authority by revealing just what you need to know to be fluent and ready for any Screening Tech Candidates challenge.</p> <p>How do I reduce the effort in the Screening Tech Candidates work to be done to get problems solved? How can I ensure that plans of action include every Screening Tech Candidates task and that every Screening Tech Candidates outcome is in place? How will I save time investigating strategic and tactical options and ensuring Screening Tech Candidates costs are low? How can I deliver tailored Screening Tech Candidates advice instantly with structured going-forward plans?</p> <p>There’s no better guide through these mind-expanding questions than acclaimed best-selling author Gerard Blokdyk. Blokdyk ensures all Screening Tech Candidates essentials are covered, from every angle: the Screening Tech Candidates self-assessment shows succinctly and clearly that what needs to be clarified to organize the required activities and processes so that Screening Tech Candidates outcomes are achieved.</p> <p>Contains extensive criteria grounded in past and current successful projects and activities by experienced Screening Tech Candidates practitioners. Their mastery, combined with the easy elegance of the self-assessment, provides its superior value to you in knowing how to ensure the outcome of any efforts in Screening Tech Candidates are maximized with professional results.</p> <p>Your purchase includes access details to the Screening Tech Candidates self-assessment dashboard download which gives you your dynamically prioritized projects-ready tool and shows you exactly what to do next. Your exclusive instant access details can be found in your book. You will receive the following contents with New and Updated specific criteria:</p> <p>- The latest quick edition of the book in PDF</p> <p>- The latest complete edition of the book in PDF, which criteria correspond to the criteria in...</p> <p>- The Self-Assessment Excel Dashboard</p> <p>- Example pre-filled Self-Assessment Excel Dashboard to get familiar with results generation</p> <p>- In-depth and specific Screening Tech Candidates Checklists</p> <p>- Project management checklists and templates to assist with implementation</p> <p>INCLUDES LIFETIME SELF ASSESSMENT UPDATES</p> <p>Every self assessment comes with Lifetime Updates and Lifetime Free Updated Books. Lifetime Updates is an industry-first feature which allows you to receive verified self assessment updates, ensuring you always have the most accurate information at your fingertips.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 6,200円

Mental Health Screening and Monitoring for Children in Care A Short Guide for Children's Agencies and Post-adoption Services【電子書籍】[ Michael Tarren-Sweeney ]

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<p><em>Mental Health Screening and Monitoring for Children in Care</em> provides a concise, step-by-step guide for children’s agencies on how to carry out mental health screening and monitoring for children and adolescents growing up in alternative care.</p> <p>Michael Tarren-Sweeney outlines unique universal mental health screening and monitoring procedures that can be implemented without the need for clinical training or professional oversight. These procedures reliably identify which children should be referred to clinical services for a comprehensive assessment, and which children do not require further assessment. Informed by recent empirical research carried out with children in foster care in Australia and the Netherlands, these procedures screen the vast majority of children who have clinical-level difficulties for a second-stage assessment, including those with attachment- and trauma-related difficulties, meaning that very few such children remain undetected.</p> <p>This book is an invaluable resource for charitable children’s agencies, children’s service providers, statutory children’s services, children’s social workers, and post-adoption support services.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 7,959円

Screening the East Heimat, Memory and Nostalgia in German Film since 1989【電子書籍】[ Nick Hodgin ]

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<p><em>Screening the East</em> considers German filmmakers’ responses to unification. In particular, it traces the representation of the East German community in films made since 1989 and considers whether these narratives challenge or reinforce the notion of a separate East German identity. The book identifies and analyses a large number of films, from internationally successful box-office hits, to lesser-known productions, many of which are discussed here for the first time. Providing an insight into the films’ historical and political context, it considers related issues such as stereotyping, racism, regional particularism and the Germans’ confrontation with the past.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 2,812円

Precise Screening of Language Disorders in Chinese Children【電子書籍】

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<p>Filling a critical gap in the field of language disorders, this book presents a scientifically validated screening system designed specifically for Chinese-speaking children.</p> <p>Combining insights from linguistics, neuroscience, and clinical paediatrics, the book presents innovative, culturally adapted diagnostic solutions that reshape the way we assess and identify language disorders in Chinese-speaking populations. The authors present a precise screening framework that uniquely integrates behavioural assessments with neurocognitive biomarkers, based on a large-scale multimodal database that includes linguistic, audiovisual, and neurocognitive data across Chinese dialects and ethnicities. The framework systematically addresses four core language skills ? listening, speaking, reading, and writing ? while taking into account the unique characteristics of Chinese language acquisition and developmental patterns.</p> <p>This essential resource will serve as a valuable guide for researchers and students in applied linguistics, paediatrics, and rehabilitation medicine. It will also appeal to professionals involved in language assessment, intervention, speech therapy, and special education language training, particularly those working with Chinese-speaking children.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 12,269円

Screening American Independent Film【電子書籍】

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<p>This indispensable collection offers 51 chapters, each focused on a distinct American independent film.</p> <p>Screening American Independent Film presents these films chronologically, addressing works from across more than a century (1915ー2020), emphasizing the breadth and long duration of American independent cinema. The collection includes canonical examples as well as films that push against and expand the definitions of "independence." The titles run from micro-budget films through marketing-friendly Indiewood projects, from auteur-driven films and festival darlings to B-movies, genre pics, and exploitation films. The chapters also introduce students to different approaches within film studies including historical and contextual framing, industrial and institutional analysis, politics and ideology, genre and authorship, representation, film analysis, exhibition and reception, and technology.</p> <p>Written by leading international scholars and emerging talents in film studies, this volume is the first of its kind. Paying particular attention to issues of diversity and inclusion for both the participating scholars and the content and themes within the selected films, <em>Screening American Independent Film</em> is an essential resource for anyone teaching or studying American cinema.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 8,290円