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商品説明価格

Learning Process-Based Therapy A Skills Training Manual for Targeting the Core Processes of Psychological Change in Clinical Practice【電子書籍】[ Stefan G. Hofmann, PhD ]

楽天Kobo電子書籍ストア
<p><strong>Step-by-step guidance for implementing process-based therapy in practice</strong></p> <p>Evidence-based mental health treatmentsーincluding cognitive behavioral therapy (CBT)ーhave long been defined in terms of scientifically validated protocols focused on syndromes. This is rapidly changing. A process focus is now emerging for evidence-based therapies, as the era of “protocols for syndromes,” passes away. This groundbreaking book offers concrete strategies for adopting a process-based approach in your clinical practice, and provides step-by-step guidance for formulating effective treatment plans.</p> <p>Written by renowned psychologists Steven C. Hayes and Stefan G. Hofmann, this manual will show you how to utilize the core competencies of process-based therapy (PBT) in a way that honors the behavioral, cognitive, and acceptance and mindfulness wings of CBT and builds bridges to other models. In the book, you’ll find a comprehensive road map to the theoretical foundations of PBT, as well as techniques for creating customized treatments that address the unique needs of each clientーleading to better therapeutic outcomes.</p> <p>Whether you’re a clinician or student of the behavioral sciences, this book has everything you need to understand and implement PBT in your work.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 5,102円

Big Data, Political Campaigning and the Law Democracy and Privacy in the Age of Micro-Targeting【電子書籍】

楽天Kobo電子書籍ストア
<p>In this multidisciplinary book, experts from around the globe examine how data-driven political campaigning works, what challenges it poses for personal privacy and democracy, and how emerging practices should be regulated.</p> <p>The rise of big data analytics in the political process has triggered official investigations in many countries around the world, and become the subject of broad and intense debate. Political parties increasingly rely on data analytics to profile the electorate and to target specific voter groups with individualised messages based on their demographic attributes. Political micro-targeting has become a major factor in modern campaigning, because of its potential to influence opinions, to mobilise supporters and to get out votes. The book explores the legal, philosophical and political dimensions of big data analytics in the electoral process. It demonstrates that the unregulated use of big personal data for political purposes not only infringes voters’ privacy rights, but also has the potential to jeopardise the future of the democratic process, and proposes reforms to address the key regulatory and ethical questions arising from the mining, use and storage of massive amounts of voter data.</p> <p>Providing an interdisciplinary assessment of the use and regulation of big data in the political process, this book will appeal to scholars from law, political science, political philosophy and media studies, policy makers and anyone who cares about democracy in the age of data-driven political campaigning.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 7,343円

Emerging Therapies Targeting the Pathophysiology of Sickle Cell Disease, An Issue of Hematology/Oncology Clinics【電子書籍】[ Elliot Vichinsky, MD ]

楽天Kobo電子書籍ストア
<p>This issue of Hematology/Oncology Clinics, guest edited by Dr. Elliott Vichinsky, is devoted to Sickle Cell Disease, and focuses on pathophysiology of hemoglobinopathies, therapeutic targets, and new approaches to correcting ineffective erythropoiesis and iron dysregulation. Articles in this issue include Polymerization and red cell membrane changes; Overview on reperfusion injury in the pathophysiology of SCD; Regulation of ineffective erythropoiesis in iron metabolism; Altering oxygen affinity; Cellular adhesion and the endothelium; Arginine therapy; Role of the hemostatic system on SCD pathophysiology and potential therapeutics; Adenosine signaling and novel therapies; New approaches to correcting ineffective erythropoiesis and iron dysregulation; New approaches to correcting ineffective erythropoiesis and iron dysregulation; Fetal hemoglobin induction; Gene therapy for hemoglobinopathies; and Oxidative injury and the role of antioxidant therapy.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 10,101円

洋書 Paperback, Targeting Pronunciation: Communicating Clearly in English

Glomarket
*** We ship internationally, so do not use a package forwarding service. We cannot ship to a package forwarding company address because of the Japanese customs regulation. If it is shipped and customs office does not let the package go, we do not make a refund. 【注意事項】 *** 特に注意してください。 *** ・個人ではない法人・団体名義での購入はできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 ・お名前にカタカナが入っている場合法人である可能性が高いため当店システムから自動保留します。カタカナで記載が必要な場合はカタカナ変わりローマ字で記載してください。 ・お名前またはご住所が法人・団体名義(XX株式会社等)、商店名などを含めている場合、または電話番号が個人のものではない場合、税関から法人名義でみなされますのでご注意ください。 ・転送サービス会社への発送もできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 *** ・注文後品切れや価格変動でキャンセルされる場合がございますので予めご了承願います。 ・当店でご購入された商品は、原則として、「個人輸入」としての取り扱いになり、すべてニュージャージからお客様のもとへ直送されます。 ・ご注文後、30営業日以内(通常2~3週間)に配送手続きをいたします。配送作業完了後、2週間程度でのお届けとなります。 ・まれに商品入荷状況や国際情勢、運送、通関事情により、お届けが2ヶ月までかかる場合がありますのでお急ぎの場合は注文をお控えください。 ・個人輸入される商品は、すべてご注文者自身の「個人使用・個人消費」が前提となりますので、ご注文された商品を第三者へ譲渡・転売することは法律で禁止されております。 ・関税・消費税が課税される場合があります。詳細はこちらをご確認下さい。PC販売説明文 8,286円

The Targeting of Myron May: Florida State University Gunman: Assistant DA Pushed Over the Edge【電子書籍】[ Renee Pittman ]

楽天Kobo電子書籍ストア
<p>A young, gifted Assistant District Attorney's tragic end, after revealing himself a victim of a documented high-level targeting program, enforced by patented, highly advanced psycho-physical technologies, reporting it covertly destroyed his life and career. He met his demise after opening fire at Florida State University's Strozier Library, just after midnight, November 20, 2014, injuring three and his quest for "Suicide by Cop."</p> <p>"My deepest regret is that I did not make a more diligent effort of documenting my experiences as a Targeted Individual along the way; however, this document is my feeble attempt at recounting my experiences thus far. First off, to anyone that may read this document, take a brief moment to pray for my soul.<br /> What I am about to do I have deep regret for; however, I feel that my options are extremely limited.Because I am a targeted individual, everything has been taken away from me. I have literally been robbed of life through psychological, financial, and emotional hardship..." - November 17, 2014 Excerpt from Myron May: "My Experiences of Being Targeted."</p> <p>On November 20, 2014, at 12:26 a.m., Myron De Shawn May, entered Florida State University, Strozier Library, and opened fire injuring three, two of whom were students, and the third an alum employee. The media reported that by 12:30 a.m., a mere 4 minutes later, May lay face down, dead, after a hail of bullets just outside the library door by law enforcement after refusing to relinquish his weapon. Initial media reports vary as to whether he shot first.<br /> Prior to the shooting, Myron May via Certified Mail sent out ten packages to various associates and social network contacts across the United States hoping to detail his story after his death. He strategically planned for the packages to arrive the day after the shooting. Although the Postal Inspector, and FBI, intercepted and confiscated the packages across the United States immediately, weeks later six letters would surface which May created by email of the information inside the packages.</p> <p>His suicide letter and YouTube video provide insight into the anguish and a well-organized mind that had, it appears, "devised a scheme" for permanent emotional relief.The emailed information within the certified mailings laid the foundation for this book.In Myron May's own words, his last wish, stated within his suicide letter, was that his painful story never dies.</p> <p>AUTHOR'S NOTE: Today there are thousands reporting being used as human guinea pigs, who are fighting the good fight, refusing to bend or break! The nationwide goal instead is that awareness of covert, monstrous, highly perfected technologies, after DECADES of research, TESTING, and development programs will save lives.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 926円

Tissue-Specific Vascular Endothelial Signals and Vector Targeting, Part A【電子書籍】[ Renata Pasqualini ]

楽天Kobo電子書籍ストア
<p>The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.</p> <p>This thematic volume reviews the latest research findings in the area of vascular proteomics related to the receptors of the vascular endothelium, and expands insights into diseases that exhibit distinct vascular characteristics, including cancer, obesity, and inflammation.</p> <ul> <li>Provides contrasting roles of VEGF, giving researchers a better understanding of the underlying mechanisms of VEGF</li> <li>Includes chapters that review research employing a variety of organisms, allowing researchers to compare and contrast</li> <li>Focuses on material that translates basic research to real-life treatment applications, showing primary researchers how the basic science is being used in the clinical setting</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 19,307円

洋書 Paperback, Cognitive-Behavioral Therapy for Adult ADHD: Targeting Executive Dysfunction

Glomarket
*** We ship internationally, so do not use a package forwarding service. We cannot ship to a package forwarding company address because of the Japanese customs regulation. If it is shipped and customs office does not let the package go, we do not make a refund. 【注意事項】 *** 特に注意してください。 *** ・個人ではない法人・団体名義での購入はできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 ・お名前にカタカナが入っている場合法人である可能性が高いため当店システムから自動保留します。カタカナで記載が必要な場合はカタカナ変わりローマ字で記載してください。 ・お名前またはご住所が法人・団体名義(XX株式会社等)、商店名などを含めている場合、または電話番号が個人のものではない場合、税関から法人名義でみなされますのでご注意ください。 ・転送サービス会社への発送もできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 *** ・注文後品切れや価格変動でキャンセルされる場合がございますので予めご了承願います。 ・当店でご購入された商品は、原則として、「個人輸入」としての取り扱いになり、すべてニュージャージからお客様のもとへ直送されます。 ・ご注文後、30営業日以内(通常2~3週間)に配送手続きをいたします。配送作業完了後、2週間程度でのお届けとなります。 ・まれに商品入荷状況や国際情勢、運送、通関事情により、お届けが2ヶ月までかかる場合がありますのでお急ぎの場合は注文をお控えください。 ・個人輸入される商品は、すべてご注文者自身の「個人使用・個人消費」が前提となりますので、ご注文された商品を第三者へ譲渡・転売することは法律で禁止されております。 ・関税・消費税が課税される場合があります。詳細はこちらをご確認下さい。PC販売説明文 7,856円

A Teacher Shoots Back Targeting School Violence【電子書籍】[ Gary Weart ]

楽天Kobo電子書籍ストア
<p><em>A Teacher Shoots Back</em> is the story of how Gary Weart became a social studies teacher in the public school systems of North Carolina and lost thirteen students to violence. With Angela Bynum, Gary started Students Against Violence Everywhere, or SAVE, with chapters extending to forty-four states and seven foreign countries. Working with mayors, governors, senators, congressmen, and two U.S. presidents, Gary worked tirelessly to encourage safe learning environments, homes, and communities. In 1995, Gary received the Presidential Service Award from President Bill Clinton. Now retired, his mission has expanded to promoting global peace and protecting the environment.</p> <p><em>A Teacher Shoots Back</em> also provides insight into Gary Weart's many lifetime adventures: working in Army counter-intelligence; carrying the Olympic Torch for both the 1996 and 2002 Olympics; meeting members of the Green Bay Packers from the Vince Lombardi era; playing fantasy baseball under Baltimore Orioles manager Earl Weaver; and teaching "Slimnastics" to an all-female class.</p> <p>In this engaging memoir, Gary chronicles how the family values of his ancestors shaped the goals of his life and taught him honesty, friendship, and the necessity of cooperation. It's the story of how one person can change the world.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 468円

e-Pedia: Channel S Channel S is a UK-based, free-to-air television channel targeting the British Bangladeshi community【電子書籍】[ Wikipedia contributors ]

楽天Kobo電子書籍ストア
<p>This carefully crafted ebook is formatted for your eReader with a functional and detailed table of contents. Channel S is a UK-based, free-to-air television channel targeting the British Bangladeshi community. The channel was established on 16 December 2004, by Mahee Ferdous Jalill ? a Bangladeshi businessman in London. On Sky it had a timesharing deal with ATN Global, and then in 2005 it started to broadcast for 24 hours, 7 days a week, and is currently available on Sky channel 814. The channel claims to be the "Voice of British Bangladeshis across the world", and its slogan "Working for the community", broadcasting mainly in Bengali and occasionally in Sylheti, and programs suiting the community needs. This book has been derived from Wikipedia: it contains the entire text of the title Wikipedia article + the entire text of all the 129 related (linked) Wikipedia articles to the title article. This book does not contain illustrations. e-Pedia (an imprint of e-artnow) charges for the convenience service of formatting these e-books for your eReader. We donate a part of our net income after taxes to the Wikimedia Foundation from the sales of all books based on Wikipedia content.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 50円

Targeting the Powerful International Prospect Research【電子書籍】[ Vanessa Hack ]

楽天Kobo電子書籍ストア
<p>If your organisation wants to tap into the wealth and influence of the rich and powerful, you need to know as much about them as possible. Prospect research, already used by fund-raisers with considerable success in the USA to target key people, can make all the difference to the success or failure of your initial approach. Targeting the powerful: international prospect research is a highly practical guide to prospect research, written by a leading expert. It explains how to conduct in-depth research into a person, company or charitable foundation, and how to use the information to recommend a line of approach most likely to succeed.<br /> <strong>Contents</strong>:What is prospect research?; Setting up a prospect research department; Online, CD-ROM, the Internet or paper? Ethics, security and confidentiality; Day to day questions; Finding the prospects; Marketing your organisation to the prospect; People; Company information; Foundations and trusts; International comparisons; A report on a new country; General sources for a new country; Specific international resources; The United Kingdom; Western Europe and Scandinavia; Central and Eastern Europe; Asia-Pacific; The United States; Canada; The rest of the world; Addresses; Index.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 7,550円

Money Stock Control and Inflation Targeting in Germany A State Space Modelling Approach to the Bundesbank’s Operating Procedures and Intermediate Strategy【電子書籍】[ Claus Brand ]

楽天Kobo電子書籍ストア
<p>1.1 Intermediate strategies for monetary policy The launch of a single European currency in January 1999 has been sparking a heated debate over what strategy the European Central Bank's policy should be based on so as to distribute and maintain monetary stability in Europe. In order to pass the Bundesbank's reputation as a tough inflation fighter on to the European Central Bank there have been strong efforts to make the ECB a close copy of the Bundesbank. It might be surmised that there will be a lot of similarities in its intermediate strategies. Among other indicators, the ECB's policy will be based on the growth rate of a broad monetary aggregate consistent with its definition of price stability. As a key instrument in the new central bank's instruments, REPO operations will constitute the main refinancing source of private banks and, in addition, minimum reserve requirements have been introduced to facilitate the authority's command over the banking sector's liquidity by means of stabilising the demand for central bank money. After having introduced monetary targeting in the 1970s, in the 1980s, the Bank of England and the Fed soon abandoned it again, because of distor tions from financial innovations and currency substitution. But the Bundes bank strongly defended its intermediate strategy of monetary targeting and advocated its implementation in the European System of Central Banks.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 6,076円

【中古】Targeting Maths Dictionary

ブックサプライ
◇◆主にゆうメールによるポスト投函、サイズにより宅配便になります。◆梱包:完全密封のビニール包装または宅配専用パックにてお届けいたします。◆帯、封入物、及び各種コード等の特典は無い場合もございます◆◇【28144】全商品、送料無料! 3,150円

洋書 Paperback, 28 Powerful Home Security Solutions: How to Stop Burglars from Targeting Your Home and Stealing Your Valuables

Glomarket
*** We ship internationally, so do not use a package forwarding service. We cannot ship to a package forwarding company address because of the Japanese customs regulation. If it is shipped and customs office does not let the package go, we do not make a refund. 【注意事項】 *** 特に注意してください。 *** ・個人ではない法人・団体名義での購入はできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 ・お名前にカタカナが入っている場合法人である可能性が高いため当店システムから自動保留します。カタカナで記載が必要な場合はカタカナ変わりローマ字で記載してください。 ・お名前またはご住所が法人・団体名義(XX株式会社等)、商店名などを含めている場合、または電話番号が個人のものではない場合、税関から法人名義でみなされますのでご注意ください。 ・転送サービス会社への発送もできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 *** ・注文後品切れや価格変動でキャンセルされる場合がございますので予めご了承願います。 ・当店でご購入された商品は、原則として、「個人輸入」としての取り扱いになり、すべてニュージャージからお客様のもとへ直送されます。 ・ご注文後、30営業日以内(通常2~3週間)に配送手続きをいたします。配送作業完了後、2週間程度でのお届けとなります。 ・まれに商品入荷状況や国際情勢、運送、通関事情により、お届けが2ヶ月までかかる場合がありますのでお急ぎの場合は注文をお控えください。 ・個人輸入される商品は、すべてご注文者自身の「個人使用・個人消費」が前提となりますので、ご注文された商品を第三者へ譲渡・転売することは法律で禁止されております。 ・関税・消費税が課税される場合があります。詳細はこちらをご確認下さい。 2,138円

Targeting Biofilms in Translational Research, Device Development, and Industrial Sectors【電子書籍】

楽天Kobo電子書籍ストア
<p>This book offers a much-needed discussion on the targeting of biofilm-related infections. Chapters include discussions on the impact of biofilm on medical implants, industrial applications, as well as wound and tissue infections. It also offers discussions on regulatory management for industrial sectors and medical environments. Given that there continues to be a paucity of effective antimicrobial products, devices, and coatings in clinical and industrial use that effectively reduce rates of infection or biofilm-related problems, <em>Targeting Biofilms in Translational Research, Device Development, and Industrial Sectors</em>, offers a fresh and much-needed perspective aimed at helping create healthier controlled environments and safer devices.</p> <p>This comprehensive book is indispensable for industrial and academic translational researchers, device developers, and regulatory experts looking to create more effective antimicrobial products.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 18,231円

John Boyd and John Warden: Air Power's Quest for Strategic Paralysis - Sun Tzu, Aftermath of Desert Storm Gulf War, Economic and Control Warfare, Industrial, Command, and Informational Targeting【電子書籍】[ Progressive Management ]

楽天Kobo電子書籍ストア
<p>This important report has been professionally converted for accurate flowing-text e-book format reproduction. Throughout air power's inaugural century, theorists have posited numerous schemes to best exploit the air weapon's inherent flexibility and ubiquity. The evolution of air power theory has been fashioned along the way by harsh lessons of war, remarkable advances in technology, and the visionary concepts of a few select airmen.<br /> Two modern-day theorists, Colonels John Boyd and John Warden, have significantly contributed to this evolution through their respective works on strategic paralysis. Although currently in vogue in the aftermath of Desert Storm, the notion of strategic paralysis has been around for quite some time. Its historical roots reach back to the writings of the Eastern philosopher of war, Sun Tzu, and the quest for paralysis underpins all theories of strategic conventional air power in one form or another. Characterized by its nonlethal intent and promise of force economization, strategic paralysis differs markedly from the more traditional strategies of annihilation and attrition.<br /> Chapter 2 examines the idea of paralyzing, or incapacitating, one's opponent in greater detail. Although currently in vogue among civilian and military analysts of the 1991 Persian Gulf War, the notion of strategic paralysis has been around for quite some time. I trace its historical roots to the ancient writings of the Chinese philosopher of war, Sun Tzu, and demonstrate that, in one form or another, the quest for paralysis underpins all theories of strategic conventional air power. I then produce a working definition of strategic paralysis by examining this concept in light of the theoretical works of British strategist J. F. C. Fuller and German historian Hans Delbruck. This analysis reveals what strategic paralysis is and what it is not.<br /> Chapters 3 and 4 summarizes and critique the theories of strategic paralysis offered by John Boyd and John Warden. In his theory of conflict, Boyd highlights the psychological and temporal aspects of war and argues that one can paralyze an enemy by operating inside his observation-orientation-decision-action (OODA) loop. This can be accomplished by "tightening" friendly OODA loops and/or "loosening" enemy OODA loops. Thus, the key to winning in conflict lies in establishing a relative advantage over one's enemy in terms of both OODA loop speed and accuracy. Ultimately, this edge allows one to penetrate the opponent's "moral-mental-physical being" to negate his capability and will to resist through moral alienation, mental disorientation, and physical deprivation.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 900円

Targeting Functional Centers of the Ribosome【電子書籍】[ Chen Davidovich ]

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<p>This thesis describes research into the mode of function, inhibition, and evolution of the ribosomal catalytic center, the Peptidyl Transferase Center (PTC)--research that has already led to attempts at improving PTC antibiotics. The PhD candidate carried out two parallel studies. One using a combination of X-ray crystallography, biochemistry, molecular biology, and theoretical studies to obtain crystal structures of ribosomal particles with antibiotics that target the PTC, revealing the modes of action, resistance, cross-resistance and discrimination between ribosomes of eubacterial pathogens and eukaryotic hosts. In the second parallel study, the candidate synthesized a ribosomal substructure--one that may represent the minimal entity capable of catalyzing peptide bond formation--shedding light on the origin of the ribosome itself.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 6,076円

洋書 Paperback, Salinity Responses and Tolerance in Plants, Volume 1: Targeting Sensory, Transport and Signaling Mechanisms

Glomarket
*** We ship internationally, so do not use a package forwarding service. We cannot ship to a package forwarding company address because of the Japanese customs regulation. If it is shipped and customs office does not let the package go, we do not make a refund. 【注意事項】 *** 特に注意してください。 *** ・個人ではない法人・団体名義での購入はできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 ・お名前にカタカナが入っている場合法人である可能性が高いため当店システムから自動保留します。カタカナで記載が必要な場合はカタカナ変わりローマ字で記載してください。 ・お名前またはご住所が法人・団体名義(XX株式会社等)、商店名などを含めている場合、または電話番号が個人のものではない場合、税関から法人名義でみなされますのでご注意ください。 ・転送サービス会社への発送もできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 *** ・注文後品切れや価格変動でキャンセルされる場合がございますので予めご了承願います。 ・当店でご購入された商品は、原則として、「個人輸入」としての取り扱いになり、すべてニュージャージからお客様のもとへ直送されます。 ・ご注文後、30営業日以内(通常2~3週間)に配送手続きをいたします。配送作業完了後、2週間程度でのお届けとなります。 ・まれに商品入荷状況や国際情勢、運送、通関事情により、お届けが2ヶ月までかかる場合がありますのでお急ぎの場合は注文をお控えください。 ・個人輸入される商品は、すべてご注文者自身の「個人使用・個人消費」が前提となりますので、ご注文された商品を第三者へ譲渡・転売することは法律で禁止されております。 ・関税・消費税が課税される場合があります。詳細はこちらをご確認下さい。PC販売説明文 19,846円

Who Bit My Tail? Targeting the t Sound【電子書籍】[ Melissa Palmer ]

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<p>Tiger wakes from a dream to find a big bite on his tail ? but can he discover who is the culprit?</p> <p>This picture book targets the /t/ sound, and is part of <em>Speech Bubbles 1</em>, a series of picture books that target specific speech sounds within the story.</p> <p>The series can be used for children receiving speech therapy, for children who have a speech sound delay/disorder, or simply as an activity for children’s speech sound development and/or phonological awareness. They are ideal for use by parents, teachers or caregivers.</p> <p>Bright pictures and a fun story create an engaging activity perfect for sound awareness.</p> <p>Please see other titles in the series for stories targeting other speech sounds.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 2,105円

Deterring Russia's Revanchist Ambitions in the Baltic Republics: Putin's Threat of Hybrid Warfare Following the Ukraine and Crimean Invasions, Aggression Targeting Estonia, Latvia, and Lithuania【電子書籍】[ Progressive Management ]

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<p>This report has been professionally converted for accurate flowing-text e-book format reproduction. Russia's invasion of Ukraine and swift annexation of the Crimean Peninsula in 2014 put the West on notice. To reassert the prestige lost since the Cold War's end, Russian President Vladimir Putin galvanized his political base with the promise of revanchism. The recent case of Ukraine is particularly alarming not only due to the forceful seizure of territory but also the "hybrid" warfighting techniques employed by Russian forces. The Baltic nations of Estonia, Latvia, and Lithuania, former Soviet Republics with fledgling Western governments located on Russia's immediate border and, importantly, members of the NATO alliance, seem a logical future target for aggression. For the United States and NATO, the costs of failing to deter Russia's revanchist ambitions are clear; either initiating a costly campaign to liberate an Alliance member or allowing Russia to remake the post-Cold War order.</p> <p>In the context of the recent conflict in Ukraine and the binding nature of NATO's collective security "guarantee," this paper will examine the steps the U.S. and NATO can reasonably take to deter Russia's revanchist ambitions in the Baltic republics, particularly from the threat of hybrid warfare. It will begin by providing a brief history of the Baltic Republics and the threat posed by Russia and hybrid warfare. Next, this paper will explore the strategic interests of the main protagonists and consider the requirements for an effective deterrent strategy. Finally, it will examine various ways and means across the various instruments of power that might be applied to deter Russian aggression in the Baltics, especially from the threat of hybrid warfare. In the final analysis, it is only through resolute action in implementing policy recommendations that encompass all instruments of power that the U.S. and NATO will be able to effectively deter Russian aggression and achieve their strategic interests in the region.</p> <p>This compilation includes a reproduction of the 2019 Worldwide Threat Assessment of the U.S. Intelligence Community.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 636円

Chitosan-Based Systems for Biopharmaceuticals Delivery, Targeting and Polymer Therapeutics【電子書籍】

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<p>Chitosan is a linear polysaccharide commercially produced by the deacetylation of chitin. It is non-toxic, biodegradable, biocompatible, and acts as a bioadhesive with otherwise unstable biomolecules - making it a valuable component in the formulation of biopharmaceutical drugs.</p> <p><em>Chitosan-Based Systems for Biopharmaceuticals</em> provides an extensive overview of the application of chitosan and its derivatives in the development and optimisation of biopharmaceuticals. The book is divided in four different parts. Part I discusses general aspects of chitosan and its derivatives, with particular emphasis on issues related to the development of biopharmaceutical chitosan-based systems. Part II deals with the use of chitosan and derivatives in the formulation and delivery of biopharmaceuticals, and focuses on the synergistic effects between chitosan and this particular subset of pharmaceuticals. Part III discusses specific applications of chitosan and its derivatives for biopharmaceutical use. Finally, Part IV presents diverse viewpoints on different issues such as regulatory, manufacturing and toxicological requirements of chitosan and its derivatives related to the development of biopharmaceutical products, as well as their patent status, and clinical application and potential.</p> <p>Topics covered include:</p> <ul> <li>chemical and technological advances in chitins and chitosans useful for the formulation of biopharmaceuticals</li> <li>physical properties of chitosan and derivatives in sol and gel states</li> <li>absorption promotion properties of chitosan and derivatives</li> <li>biocompatibility and biodegradation of chitosan and derivatives</li> <li>biological and pharmacological activity of chitosan and derivatives</li> <li>biological, chemical and physical compatibility of chitosan and biopharmaceuticals</li> <li>approaches for functional modification or crosslinking of chitosan</li> <li>use of chitosan and derivatives in conventional biopharmaceutical dosage forms</li> <li>manufacture techniques of chitosan-based microparticles and nanoparticles for biopharmaceuticals</li> <li>chitosan and derivatives for biopharmaceutical use: mucoadhesive properties</li> <li>chitosan-based systems for mucosal delivery of biopharmaceuticals</li> <li>chitosan-based delivery systems for mucosal vaccination</li> <li>chitosan-based nanoparticulates for oral delivery of biopharmaceuticals</li> <li>chitosan-based systems for ocular delivery of biopharmaceuticals</li> <li>chemical modification of chitosan for delivery of DNA and siRNA</li> <li>target-specific chitosan-based nanoparticle systems for nucleic acid delivery</li> <li>functional PEGylated chitosan systems for biopharmaceuticals</li> <li>stimuli-sensitive chitosan-based systems for biopharmaceuticals</li> <li>chitosan copolymers for biopharmaceuticals</li> <li>application of chitosan for anti-cancer biopharmaceutical delivery</li> <li>chitosan-based biopharmaceuticals scaffolds in tissue engineering and regenerative medicine</li> <li>wound healing properties of chitosan and its use in wound dressing biopharmaceuticals</li> <li>toxicological properties of chitosan and derivatives for biopharmaceutical applications</li> <li>regulatory status of chitosan and derivatives</li> <li>patentability and intellectual property issues</li> <li>quality control and good manufacturing practice</li> <li>preclinical and clinical use of chitosan and derivatives for biopharmaceuticals</li> </ul> <p><em>Chitosan-Based Systems for Biopharmaceuticals</em> is an important compendium of fundamental concepts, practical tools and applications of chitosan-based biopharmaceuticals for researchers in academia and industry working in drug formulation and delivery, biopharmaceuticals, medicinal chemistry, pharmacy, bioengineering and new materials development.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 23,099円

Among the Dead Cities Is the Targeting of Civilians in War Ever Justified?【電子書籍】[ Professor A. C. Grayling ]

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<p>Britain and the USA carried out a massive bombing offensive against the cities of Germany and Japan in the course of the Second World War, which ended with the destruction of Hamburg, Dresden, Tokyo, Hiroshima and Nagasaki. Was the bombing of civilian targets justified by the necessities of war? Or was it, in fact, a crime against humanity? How should we, the descendants of the Allies who won the victory in that war, reply to the moral challenge of the descendants of those whose cities were targeted? A.C. Grayling looks at the stands people took, both for and against, and crucially asks what are the lessons that we can learn for today about how people should behave in a world of tension and moral confusion, of terrorism and fragile democracies. <em>Among the Dead Cities</em> is both a lucid and revealing work of modern history and an investigation of conscience into one of the last remaining controversies of that time.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 1,153円

Zack the Buzzy Bee Targeting the z Sound【電子書籍】[ Melissa Palmer ]

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<p>Zack just wants to find other bees that look like him ? and he meets some interesting and different kinds of bees along the way.</p> <p>This picture book targets the /z/ sound and is part of <em>Speech Bubbles 2</em>, a series of picture books that target specific speech sounds within the story.</p> <p>The series can be used for children receiving speech therapy, for children who have a speech sound delay/disorder, or simply as an activity for children’s speech sound development and/or phonological awareness. They are ideal for use by parents, teachers or caregivers.</p> <p>Bright pictures and a fun story create an engaging activity perfect for sound awareness.</p> <p>Picture books are sold individually, or in a pack. There are currently two packs available ? <em>Speech Bubbles 1</em> and <em>Speech Bubbles 2.</em> Please see further titles in the series for stories targeting other speech sounds.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 2,105円

Brain Tumor Targeting Drug Delivery Systems Advanced Nanoscience for Theranostics Applications【電子書籍】[ Ram Kumar Sahu ]

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<p>Brain Tumor Targeting Drug Delivery Systems: Advanced Nanoscience for Theranostics Applications is a comprehensive reference focused on the latest advancements in nanotechnology for brain tumor therapy. With practical insights and cutting-edge research, this book equips readers with the knowledge to develop innovative drug delivery systems for effective brain tumor diagnosis and treatment.Structured into insightful chapters, this book covers the anatomy, physiology, and pathophysiology of the brain, addressing barriers to targeted drug delivery strategies. Chapters explore theranostics-based delivery systems, including polymeric nanoparticles, liposomes, dendrimers, nanoemulsions, micelles, and inorganic nanoparticles, for precise brain tumor diagnosis and treatment.This informative resource is designed for students and research scholars in pharmacology, pharmaceutical industry scientists, professors, and clinical medicine researchers. With comprehensive chapters and references for further reading, this book facilitates easy understanding of the intricate nanomedical technology, empowering researchers to make significant strides in the field of brain tumor therapy.Key Features: - Structured chapters for easy understanding of nanotechnology concepts - In-depth coverage of theranostics-based delivery systems for brain tumor diagnosis and treatment - References for further reading and exploring new advances in drug delivery systems</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 4,759円

Anti-Cancer N-Heterocyclic Carbene Complexes of Gold(III), Gold(I) and Platinum(II) Thiol “Switch-on” Fluorescent Probes, Thioredoxin Reductase Inhibitors and Endoplasmic Reticulum Targeting Agents【電子書籍】[ Taotao Zou ]

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<p>This thesis focuses on the development of gold- and non-classical platinum-based anti-cancer agents that display distinctively different anti-cancer mechanisms compared to the commonly used cisplatin. These metal complexes contain N-heterocyclic carbene (NHC) ligands which are able to form strong M-C(NHC) bonds, conferring high stability and favorable lipophilicity, reactivity and binding specificity of metal complexes on biomolecules. The author demonstrates significant advances made in anti-cancer gold(III), gold(I) and platinum(II) complexes. Detailed chemical synthesis, in vitro and/or in vivo anti-cancer activities are clearly presented including: (i) a class of Au(III) complexes containing a highly fluorescent N^N^N ligand and NHC ligand that simultaneously act as fluorescent thiol “switch-on” probes and anti-cancer agents; (ii) a dinuclear gold(I) complex with a mixed diphosphine and bis(NHC) ligand displaying favorable stability and showing significant inhibition of tumor growth in two independent mice models with no observable side effects; and (iii) a panel of stable luminescent cyclometalated platinum(II) complexes exhibiting high specificity to localize to the endoplasmic reticulum (ER) domain, inducing ER stress and cell apoptosis. These works highlight the clinical potential that gold and platinum complexes offer for cancer treatment.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 12,154円

Targeting Trafficking in Drug Development【電子書籍】

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<p>Cellular trafficking is only recently identified as a site for therapeutic intervention. This book provides up to date information on the mechanism for exploiting this area for drug development as well as a clear understanding of the individual components of cellular trafficking. The authors are experts in their areas and the book features tables and figures that enable comparison and clear understanding.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 26,619円

Phytochemicals Targeting Tumor Microenvironment in Gastrointestinal Cancers【電子書籍】

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<p>Gastrointestinal (GI) malignancies account for a large portion of cancers worldwide. Although incidence of esophageal, gastric, and colorectal cancers has decreased in recent years, pancreatic and liver cancer have increased. The mainstay of GI cancer therapy is chemoradiation and surgery. Despite significant medical advancements, diagnosis and therapy for GI cancers remain challenging due to tumor cell resistance to chemoradiotherapy. The tumor’s increased cell signalling due to excessive transcription factor activation and increased stellate cell activity leads to collagen deposition formation of a dense stroma around the tumor, which prevents drugs from reaching the malignant cells. This leads to tumor chemoresistance.</p> <p>To circumvent these difficulties, drug therapy targeting the tumor’s specific microenvironment and the additive anticancer effect of phytochemicals can allow for more effective treatment. This volume will be the first on the market on the topic of phytochemicals and their effect on the tumor microenvironment (TME). TME is an emerging area of research and the book will be a welcome introductory addition to the field.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 18,231円

Targeting the Third Reich Air Intelligence and the Allied Bombing Campaigns【電子書籍】[ Rober S. Ehlers Jr. ]

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<p>When large formations of Allied four-engine bombers finally flew over Europe, it marked the beginning of the end for the Third Reich. Their relentless hammering of Germany--totaling more than 1.4 million missions--took out oil refineries, industries, and transportation infrastructures vital to the Reich's war effort. While other accounts have focused on operational details, this is the first book to reveal the crucial role of air intelligence in these dramatic campaigns.</p> <p>Robert Ehlers reexamines these bombings through the lens of both air intelligence and operations, a dual approach that shows how the former was so vital to the latter's success. Air intelligence was essential to both targeting and damage assessment, and by demonstrating its contributions to the Combined Bomber Offensive of 1943-1945, Ehlers provides a wealth of new insight into the war.</p> <p>Ehlers describes the close ties that developed between the Royal Air Force's "precision intelligence" arm and the U.S. Army Air Force's "precision bombardment" forces, telling how the RAF's photographic reconnaissance and signals intelligence steered both British and American bombers to the right targets at the right intervals with the right munitions. He shows that the greatest strength of this partnership was its ability to orchestrate all aspects of damage assessment within an effective organizational structure, so that by 1944 senior air commanders--like the RAF's Arthur "Bomber" Harris and the AAF's Carl "Tooey" Spaatz--could gauge the accuracy of bombing with a high degree of precision, analyze its effects on the German war effort, and determine its effectiveness in helping the Allies achieve strategic objectives.</p> <p>Ehlers focuses on three key offensives in 1944--against French and Belgian rail supply lines delivering German troops and supplies to Normandy, against German oil refineries, and against railroads and waterways inside the Reich--that had a disastrous effect on the Nazi war effort. In the process, he underscores the degree to which bombers constituted part of a highly effective combined-arms force, giving Allied armies crucial advantages on the battlefield. Drawing on a huge collection of bomb-damage assessment photographs and a wealth of other archival sources, he shows that the success of these and other efforts can be traced directly to the success of air intelligence.</p> <p>Providing a deeper and more accurate understanding of the bomber campaigns' role in the Allied victory, Ehlers's study testifies to the strategic importance of these efforts in that war and provides a tool for understanding the importance of intelligence operations in future conflicts.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 4,268円

Multistate GTPase Control Co-translational Protein Targeting【電子書籍】[ Xin Zhang ]

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<p>Proteins act as macromolecular machinery that mediate many diverse biological processes - the molecular mechanisms of this machinery has fascinated biologists for decades. Analysis of the kinetic and thermodynamic features of these mechanisms could reveal unprecedented aspects of how the machinery function and will eventually lead to a novel understanding of various biological processes. This dissertation comprehensively demonstrates how two universally conserved guanosine triphosphatases in the signal recognition particle and its membrane receptor maintain the efficiency and fidelity of the co-translational protein targeting process essential to all cells. A series of quantitative experiments reveal that the highly ordered and coordinated conformational states of the machinery are the key to their regulatory function. This dissertation also offers a mechanistic view of another fascinating system in which multistate protein machinery closely control critical biological processes.</p> <p>Written while completing graduate work at California Institute of Technology.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 6,076円

21st Century U.S. Military Manuals: The Targeting Process - Field Manual 3-60 - Principles and Philosophy, Dynamic Targeting (Professional Format Series)【電子書籍】[ Progressive Management ]

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<p>Professionally converted for accurate flowing-text e-book format reproduction, this Army Field Manual describes the targeting process used by the United States Army. The FM 3-60 is descriptive and not prescriptive in nature. This manual has applicability in any theater of operations. The manual offers considerations for commanders and staffers in preparing for challenges with targeting, yet it is flexible enough to adapt to dynamic situation. FM 3-60 replaces FM 6-20-10, Tactics, Techniques, and Procedures for the Targeting Process.</p> <p>The development and research of FM 3-60 parallels similar ongoing efforts by other Army proponents to develop their own supporting branch doctrine and tactics, techniques, and procedures for the division, support brigades, brigade combat teams, and subordinate elements.</p> <p>Field Manual (FM) 3-60, The Targeting Process consists of five chapters and eight appendices to describe the Army's targeting process. Each chapter and appendix addresses how the decide, detect, deliver, and assess (D3A) methodology enhances the targeting process. The D3A is a methodology which optimizes the integration and synchronization of maneuver, fire support, and intelligence from task force to corps level operations. The D3A is described without tying it to specific hardware that will eventually become dated. The Army's targeting process consists of time tested techniques organized in a systematic framework.</p> <p>The FM 3-60 addresses how D3A methodology interfaces with the joint targeting cycle, military decisionmaking process (MDMP), and operations process. The joint targeting fundamental principles and doctrinal guidance are also presented in this publication.</p> <p>Successful targeting requires that the leadership team and their staff possess an understanding of the functions associated with the targeting process. The FM 3-60 builds on the collective knowledge, experience gained through recent operations, and numerous exercises. The manual is rooted in time tested principles and fundamentals, while accommodating force design, new technologies, and diverse threats to national security.</p> <p>The targeting process is challenging. The challenge includes locating, identifying, classifying, tracking, and attacking targets and assessing battle damage with limited assets and weapon systems, which makes this process complicated. The process becomes even more difficult with long range and fast moving targets. It is even more complex at division and higher echelons with more decisionmakers, acquisitions, surveillance assets, and weapon systems. This challenge is particularly true when joint and combined assets are included. The competition for assets is intense. Many intelligence systems are capable of situation development, target acquisition, and battle damage assessment (BDA), but may not be able to do all at the same time. Detailed guidance, thorough planning, and disciplined execution prevent unnecessary redundancy and make the most of available combat power.</p> <p>Chapter 1 begins with the basics and introduction to targeting.</p> <p>Chapter 2 describes the Army's targeting process in detail.</p> <p>Chapter 3 addresses targeting at the corps and division level.</p> <p>Chapter 4 addresses targeting at the brigade combat team and battalion level.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 1,057円

Targeting Top Terrorists Understanding Leadership Removal in Counterterrorism Strategy【電子書籍】[ Lt. Col. Bryan C. Price ]

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<p>When President Barack Obama announced the assassination of Osama bin Laden, many Americans hoped the killing of al-Qaida’s leader would sound the death knell for the organization. Since 9/11, killing and capturing terrorist leaders has been a central element in U.S. counterterrorism strategy. This practice, known as leadership decapitation, is based on the logic that removing key figures will disrupt the organization and contribute to its ultimate failure. Yet many scholars have argued that targeted killings are ineffective or counterproductive, questioning whether taking out a terror network’s leaders causes more problems than it solves.</p> <p>In <em>Targeting Top Terrorists</em>, Bryan C. Price offers a rich, data-driven examination of leadership decapitation tactics, providing theoretical and empirical explanations of the conditions under which they can be successful. Analyzing hundreds of cases of leadership turnover from over two hundred terrorist groups, Price demonstrates that although the tactic may result in short-term negative side effects, the loss of top leaders significantly reduces terror groups’ life spans. He explains vital questions such as: What factors make some terrorist groups more vulnerable than others? Is it better to kill or capture terrorist leaders? How does leadership decapitation compare to other counterterrorism options? With compelling evidence based on an original dataset along with an in-depth case study of Hamas, <em>Targeting Top Terrorists</em> contributes to scholarship on terrorism and organizational theory and provides insights for policy makers and practitioners on some of the most pressing debates in the field.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 3,631円