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74件中 1件 - 30件
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商品 | 説明 | 価格 |

Evolution of Extracellular Matrix【電子書籍】
楽天Kobo電子書籍ストア
|
<p>The evolution of single cells into multicellular organisms was mediated, in large part, by the extracellular matrix. The proteins and glycoconjugates that make up the extracellular matrix provide structural support to cellular complexes, facilitate cell adhesion and migration, and impart mechanical properties that are important for tissue function. Each class of ECM macromolecule has evolved to incorporate distinctive properties that are defined by conserved modules that are mixed together to achieve appropriate function. This volume provides a comprehensive analysis of how the major ECM components evolved over time in order to fill their specific roles found in modern organisms. The major focus is on the structural matrix proteins, matricellular proteins, and more complex ECM structures such as basement membranes. Adhesive proteins and their receptors are also discussed.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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18,231円
|

Connective Tissue Disease Molecular Pathology of the Extracellular Matrix【電子書籍】
楽天Kobo電子書籍ストア
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<p>This book is a collection of works that canvass many of the recent developments in various areas of connective tissue research. It focuses on the structure of the components, molecular organization and pathology of the extracellular matrix.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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63,317円
|

【中古】【輸入品・未使用】Extracellular Sugar-Based Biopolymers Matrices (Biologically-Inspired Systems%カンマ% 12)
ムジカ&フェリーチェ楽天市場店
|
【中古】【輸入品・未使用】Extracellular Sugar-Based Biopolymers Matrices (Biologically-Inspired Systems%カンマ% 12)【メーカー名】Springer【メーカー型番】【ブランド名】Springer【商品説明】Extracellular Sugar-Based Biopolymers Matrices (Biologically-Inspired Systems%カンマ% 12)当店では初期不良に限り、商品到着から7日間は返品を 受付けております。こちらは海外販売用に買取り致しました未使用品です。買取り致しました為、中古扱いとしております。他モールとの併売品の為、完売の際はご連絡致しますのでご了承下さい。速やかにご返金させて頂きます。ご注文からお届けまで1、ご注文⇒ご注文は24時間受け付けております。2、注文確認⇒ご注文後、当店から注文確認メールを送信します。3、配送⇒当店海外倉庫から取り寄せの場合は10〜30日程度でのお届けとなります。国内到着後、発送の際に通知にてご連絡致します。国内倉庫からの場合は3〜7日でのお届けとなります。 ※離島、北海道、九州、沖縄は遅れる場合がございます。予めご了承下さい。お電話でのお問合せは少人数で運営の為受け付けておりませんので、メールにてお問合せお願い致します。営業時間 月〜金 10:00〜17:00お客様都合によるご注文後のキャンセル・返品はお受けしておりませんのでご了承下さい。
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71,557円
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Extracellular Matrix and Egg Coats【電子書籍】[ Eveline Litscher ]
楽天Kobo電子書籍ストア
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<p>Extracellular Matrix and Egg Coats, Volume 130, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on The Human Egg's Zona Pellucida, the Structure of Zona Pellucida Module Proteins, The Fish Egg's Zona Pellucidam The Chicken Egg's Zona Pellucidam The Marsupial Egg's Zona Pellucida, the Evolution of Zona Pellucida Proteins, The Mouse Egg's Zona Pellucida, Aspects of ECM, ECM and Morphogenesis, Collagen fibril assembly and function, The Ear's Tectorial Membrane, ECM and Cell Fate, and the Aspects of ECM. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Current Topics in Developmental Biology series - Updated release includes the latest information on the Extracellular Matrix in Development</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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22,205円
|

Extracellular Matrix-derived Implants in Clinical Medicine【電子書籍】
楽天Kobo電子書籍ストア
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<p>Extracellular Matrix-Derived Implants in Clinical Medicine comprehensively covers the emergence of tissue engineering and regenerative medicine over the past few decades, along with discussions of continuous funding and research. The book provides a state-of-the-art review of this increasingly important technology and how it is translating from bench to bedside. Part One of the book looks at the historical use of human and animal tissues, focusing on the main application areas, including cardiovascular, hard and soft tissue engineering, and neurological, while Part Two examines the challenges in harvesting, processing, and manufacturing of extracellular matrices, with a final section reviewing the international regulatory environment and economics of tissue-based products. - Addresses issues of tissue engineering and regenerative medicine from a biomaterials industry perspective - Looks at the historical use of human and animal tissues, focusing on the main application areas, including cardiovascular, hard and soft tissue engineering, and neurological - Examines the challenges in harvesting, processing, and manufacturing of extracellular matrices - Reviews the international regulatory environment and economics of tissue-based products</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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24,848円
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Handbook of the Extracellular Matrix Biologically-Derived Materials【電子書籍】
楽天Kobo電子書籍ストア
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<p>This book comprises 6 sections covering the fundamentals of the extracellular matrix, as well as the development and challenges of using biologically-derived materials, and its advanced biomedical applications. The first section is dedicated to the extracellular matrix, while the other 5 sections are each dedicated to a particular type of material. This book reports the fundamentals of the extracellular matrix and its impact on the development of innovative materials; provides an overview of the advanced methodologies used to develop biologically-derived materials; and describes the challenges of the synthesis and processing of the different materials. Furthermore, it presents the biological activities, structural and physicochemical properties of such materials, and the modification methods pursued to improve their inherent properties. The wide range of advanced applications are covered as well, including the combination with emerging technologies, underlying tissue-engineered scaffolding, drug delivery systems, 3D in vitro tissue and cancer models, 3D bioprinted models, bioinks, and more.</p> <p>This reference work serves as a core reference for multidisciplinary students (undergraduates and Ph.D. students) and a wide range of established researchers and professionals working in the medical field, e.g., orthopaedics, radiology, dentistry, and cancer.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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60,774円
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Neurochemistry Study Guide: Membranes And Transport, Ion Channels, Extracellular Signaling, Neurotransmitters & More. (Mobi Medical)【電子書籍】[ MobileReference ]
楽天Kobo電子書籍ストア
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<p>Neurochemistry Study Guide Audience: Intended for everyone interested in Neurochemistry, particularly undergraduate and graduate life science students, medical students, and nursing students.FEATURES:- Fully illustrated Synthesis and degradation pathways. Written in clear, concise format. Difficult concepts are explained in simple terms. - Navigate from Table of Contents or search for the words or phrases- Access the guide anytime, anywhere - at home, on the train, in the subway. Use your down-time to prepare for an exam. - Always have the guide available for a quick reference. TABLE OF CONTENTS:I. Neurocellular AnatomyNeuron: Axon DendriteAxonal Transport and Growth: Axoplasmic transport Kinesin Dynein Myosin Growth cone Axon guidanceSynapse: Synaptic Vesicles Exocytosis Endocytosis Synaptic plasticity SNARE Synaptobrevin Synapsin NSFGlial cell: Astrocyte Oligodendrocyte Schwann cell Myelin Nodes of Ranvier Multiple sclerosisCytoskeleton: Actin Intermediate filament MicrotubuleII. Membranes And TransportMembrane Structure: Fluid mosaic model Detailed StructureLipids: Fatty acid Fatty acid degradation Fatty acid synthesis Triglyceride Waxes Lipoprotein CholesterolMembrane Components: Phospholipids Sphingomyelin Glycolipid Glycocalix Cholesterol AntigenMovement of Molecules: Diffusion Osmosis Electrochemical gradientPassive transport: Facilitated diffusion Ion channelActive transport: ATP-Dependent Na/K Pump V-ATPase Proton pump Electron transport Antiporter SymporterBlood-brain barrier: Tight junction Cerebrospinal fluidIII. Ion ChannelsChannels: Ion channel Gap junctionVoltage-gated: Potassium channel Sodium channel BK channel Inward-rectifier potassium ion channel Resting channels Calcium channelLigand-gated: NMDA receptor AMPA receptor Kainate receptor Nicotinic acetylcholine receptor Glycine receptor GABA A receptor GABA B receptor GABA C receptorOther ion channels: Cyclic nucleotide-gated Stretch-activated G-protein-gated Light-gatedIV. Extracellular SignalingAcetylcholine: Degradation by acetylcholinesterase Receptors Overview Nicotinic Receptors Muscarinic Receptors Muscarinic receptor agonistCatecholamines: Epinephrine Norepinephrine Norepinephrine transporter Dopamine Dopamine transporter Levodopa Catecholamines breakdown Adrenergic receptor Dopamine receptorMajor dopamine pathways: Mesocortical pathway Nigrostriatal pathway Mesolimbic pathway Tuberoinfundibular pathwaySerotonin: Serotonin transporter Selective serotonin reuptake inhibitor ReceptorsHistamine: H1 receptor H2 receptor H3 receptor H4 receptors Antihistamine drugsGlutamate: NMDA receptor AMPA receptor Kainate receptor Glutamate transporter</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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1,349円
|

Multi-scale Extracellular Matrix Mechanics and Mechanobiology【電子書籍】
楽天Kobo電子書籍ストア
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<p>This book describes the current state of knowledge in the field of multi-scale ECM mechanics and mechanobiology with a focus on experimental and modelling studies in biomechanical characterization, advanced optical microscopy and imaging, as well as computational modeling. This book also discusses the scale dependency of ECM mechanics, translation of mechanical forces from tissue to cellular level, and advances and challenges in improving our understanding of cellular mechanotransduction in the context of living tissues and organisms.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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12,154円
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Extracellular Vesicles【電子書籍】[ Sheila Spada ]
楽天Kobo電子書籍ストア
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<p>Extracellular Vesicles, Volume 645 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include Genetic labeling of extracellular vesicle exosomes for studying biogenesis and uptake in living mammalian cells, Fluorescent Labeling of Extracellular Vesicles, Isolation of extracellular vesicles from lymph, Transgenic rats for tracking body fluid/tissue-derived extracellular vesicles, Isolation of amniotic extracellular vesicles, Urinary extracellular vesicle isolation, Immunocapture-based ELISA to Characterize and Quantify Extracellular Vesicles in Both Cell Culture Supernatants and Body Fluids, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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21,041円
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Extracellular Vesicle: Biology and Translational Application【電子書籍】
楽天Kobo電子書籍ストア
|
<p>This book focuses on the applications of extracellular vesicles (EVs) for regenerative medicine. EVs are small, lipid-bound vesicles carrying cargo that can be released by virtually all cell types. Over the past decades, the field of EV research has experienced exponential growth. Once dismissed as mere cellular debris, EVs are now recognized as sophisticated messengers, facilitating the transmission of crucial information between cells and orchestrating a myriad of biological processes. Notably, stem cell-derived EVs hold particular promise in regenerative therapeutic applications. Rich in the functional components of stem cells, these EVs offer an alternative approach to cell therapy for tissue repair and regeneration. The purpose of this book is to provide an overview of EVs on their biology, function, and potential applications. The book starts with exploring the intricate biology of EVs, their cargo, and their unique ability to modulate cellular processes. It discusses the therapeutic potential of EVs in various diseases, as well as the approaches for the bionanotechnological development of artificial EVs for theranostics. Large-scale EV isolation methods and their preclinical applications are also addressed. It will be useful for undergraduate and graduate students in medicine and cell biology, biologist, and others who are interested in such topic.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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19,447円
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Structure and Function of the Extracellular Matrix A Multiscale Quantitative Approach【電子書籍】[ Bela Suki ]
楽天Kobo電子書籍ストア
|
<p>Structure and Function of the Extracellular Matrix: A Multiscale Quantitative Approach introduces biomechanics and biophysics with applications to understand the biological function of the extracellular matrix in health and disease. A general multiscale approach is followed by investigating behavior from the scale of single molecules, through fibrils and fibers, to tissues of various organ systems. Through mathematical models and structural information, quantitative description of the extracellular matrix function is derived with tissue specific details. The book introduces the properties and organization of extracellular matrix components and quantitative models of the matrix, and guides the reader through predicting functional properties. This book integrates evolutionary biology with multiscale structure to quantitatively understand the function of the extracellular matrix. This approach allows a fresh look into normal functioning as well as the pathological alterations of the extracellular matrix. Professor Suki's book is written to be useful to undergraduates, graduate students, and researchers interested in the quantitative aspects of the extracellular matrix. Researchers working in mechanotransduction, respiratory and cardiovascular mechanics, and multiscale biomechanics of tendon, cartilage, skin, and bone may also be interested in this book. - Examines the evolutionary origins and consequences of the extracellular matrix - Delivers the first book to quantitatively treat the extracellular matrix as a multiscale system - Presents problems and a set of computational laboratory projects in various chapters to aid teaching and learning - Provides an introduction to the properties and organization of the extracellular matrix components</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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15,861円
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Interfaces in Particle and Fibre Reinforced Composites Current Perspectives on Polymer, Ceramic, Metal and Extracellular Matrices【電子書籍】
楽天Kobo電子書籍ストア
|
<p>Interfaces in Particle and Fibre-Reinforced Composites: From Macro- to Nanoscale addresses recent research findings on the particle-matrix interface at different length scales. The book's main focus is on the reinforcement of materials by particles that can result in a composite material of high stiffness and strength, but it also focuses on how the particle interacts with the (matrix) material, which may be a polymer, biological-based material, ceramic or conventional metal. The different types of particle reinforced composites are discussed, as is load transfer at the particle-matrix interface. Readers will learn how to select materials and about particle structure. Significant progress has been made in applying these approaches, thus making this book a timely piece on recent research findings on the particle-matrix interface at different length scales. - Features wide coverage, from polymer, to ceramics and metal-based particulate composites - Structured in a logical order to cover fundamental studies, computer simulations, experimental techniques and characterization</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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28,020円
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Extracellular Composite Matrices in Arthropods【電子書籍】
楽天Kobo電子書籍ストア
|
<p>Emphasis is placed on the elaborate cuticular matrices in insects and crustaceans, spider and insect silks, sialomes of phytophagous and blood-feeding arthropods as well as on secretions of male and female accessory glands. Focus is placed largely on insects, due to the extensive body of published research that in part is the result of available whole genome sequences of several model species (in particular Drosophila melanogaster) and accessible ESTs for other species. Such advances have facilitated fundamental insights into genomic, proteomic and molecular biology-based physiology. This new volume contains comprehensive contributions on extracellular composite matrices in arthropods. The building blocks of such matrices are formed in and secreted by single layered epithelial cells into exterior domains where their final assembly takes place.</p> <p>Additionally, the unique mechanical properties of natural biocomposites like chitin/chitosan, the crustacean mineralized exoskeleton, the pliant protein resilin or insect and spider silks, have inspired basic and applied research that yield sophistical biomimetics and structural biocomposite hybrids important for future industrial and biomedical use. In summary, this book provides an invaluable vast source of basic and applied information for a plethora of scientists as well as textbook for graduate and advanced undergraduate students.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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34,033円
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Biomedical Applications of Extracellular Vesicles【電子書籍】[ Zhenhua Li ]
楽天Kobo電子書籍ストア
|
<p><strong>Biomedical Applications of Extracellular Vesicles</strong></p> <p><strong>Unique resource focusing on biomedical applications and clinical translation of extracellular vesicles in science and medicine</strong></p> <p>Focusing on key points to better understand extracellular vesicles (EVs) and their development, <em>Biomedical Applications of Extracellular Vesicles</em> describes in detail the biogenesis of EVs, the mechanism of intercellular communication, and the treatment of various diseases of EVs and the EV-based drug delivery platforms. An application-oriented resource, the work presents rapidly newer biomedical and clinical applications of natural and engineered EVs such as drug delivery, diagnosis, prognosis monitoring, immunotherapy, and more.</p> <p>The first part of this book provides a basic background on EVs. Next, the book introduces the excellent therapeutic effects of EVs themselves and the underlying mechanisms, followed by how EVs from different sources were used to construct drug delivery platforms. The latest research on EVs from leading groups around the world is presented.</p> <p>Sample topics covered in <em>Biomedical Applications of Extracellular Vesicles</em> include:</p> <ul> <li>Biogenesis of various EVs</li> <li>Pros and cons of the different instrumental and methodological developments for analytical strategies applied to EVs</li> <li>EVs in treatment of major diseases, such as cancer, cardiovascular and respiratory diseases</li> <li>Current methods of engineering EVs, and a comparison of the advantages and disadvantages of each method</li> <li>Biomaterials, such as hydrogels, scaffolds, and microneedles, that have been developed to further enhance the therapeutic efficacy of EVs</li> <li>Key challenges, such as quality control, scalability, and biosafety, that limit the clinical and industrial translation of EVs</li> </ul> <p>Explaining in detail how extracellular vesicles are produced and engineered, along with potential applications and commercial developments of EVs in science and industry, <em>Biomedical Applications of Extracellular Vesicles</em> is an essential resource on the subject for chemists, cell biologists, and molecular physicists.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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21,351円
|

Fungal Extracellular Vesicles Biological Roles【電子書籍】
楽天Kobo電子書籍ストア
|
<p>This book provides an in-depth overview on the manifold functions of fungal extracellular vesicles (EV) which span from cell-to-cell communication, pathogenicity and stimulation of host’s immunity to export of hundreds of biomolecules. The book summarizes the present knowledge on the impact of extracellular vesicles on fungal biology. Extracellular vesicles participate in fundamental biological processes in all living cells but only during the last 15 years the production and functions of EVs were identified and studied in fungal species too. Up to date more than 50 independent studies have shown that extracellular vesicles are produced by at least 20 fungal species.</p> <p>The book addresses researchers and advanced students in Microbiology, Mycology and Biotechnology.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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20,662円
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Ion Channel Factsbook Extracellular Ligand-Gated Channels【電子書籍】[ Edward Conley ]
楽天Kobo電子書籍ストア
|
<p>How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, sequence information, gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact? The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload. Each volume provides a catalogue of the essential properties of families of molecules. Gene organization, sequence information, physicochemical properties, and biological activity are presented using a common, easy to follow format. Taken together they compile everything you wanted to know about proteins but were too busy to look for.In a set of four inter-related volumes, The Ion Channel FactsBook provides a comprehensive framework of facts about channel molecules central to electrical signalling phenomena in living cells. The first volume is devoted to Extracellular Ligand-Gated Integral Receptor-Channel Families including those molecular complexes activated by: 5-Hydroxytryptamine, ATP, Glutamate, Acetylcholine, GABA, Glycine. - Nomenclature - Expression - Sequence analyses - Structure and function - Electrophysiology - Pharmacology - Information retrieval</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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11,208円
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Extracellular Matrix Biomineralization of Dental Tissue Structures【電子書籍】
楽天Kobo電子書籍ストア
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<p>This book addresses the structural and biological properties of dental and peridental tissue structures and covers their mineralization process. The book contains a description of dentines, cementum, enamel and bone, including collagens, as well as non-collagenous proteins (SIBLINGs, SLRPs, GAGs, PGs, lipids, and MMPs).</p> <p>The mechanisms of mineralization are described in detail and the book is focused on matrix vesicles, collagen mineralization and the role of non-collagenous extracellular matrix components either as promoters or inhibitors of mineralization. In addition, the matrix components (non-collagenous) of enamel (amelogenin, ameloblastin, enamelin, MMP4, MMP20 and other proteases) are reviewed and their respective roles in dental tissues biomineralizations and tissue turnover are discussed. Additionally, environmental factors involved in enamel / dentin defects are adressed.</p> <p>With state-of-the-art contributions from experts in the respective domains, the book is a useful introduction to the field for junior scientists, interested in dental and peridental tissue biomineralization. It is also an interesting read for advanced scientists and clinicians working in dental research, giving them a broader view of the topic beyond their area of specialization.</p> <p>The series <em>Biology of Extracellular Matrix</em> is published in collaboration with the American Society for Matrix Biology.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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12,154円
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Extracellular Glycolipids of Yeasts Biodiversity, Biochemistry, and Prospects【電子書籍】[ Ekaterina Kulakovskaya ]
楽天Kobo電子書籍ストア
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<p>Extracellular Glycolipids of Yeasts: Biodiversity, Biochemistry, and Prospects provides a comprehensive view of the biochemistry, biological activity, and practical application of extracellular glycolipids of yeast. This book brings much-needed clarity to the complex topic of glycolipids and streamlines the rather confusing terminology used for glycolipids. It also provides a wealth of modern data on their composition, structure and properties, biosynthetic pathways, methods of isolation and identification, antifungal activity, and mechanisms of action. Studies of extracellular glycolipids of yeast now draw the attention of researchers in life science and biotechnology due to numerous recently revealed biological properties of these compounds. These compounds are scientifically and practically promising in medicine and agriculture due to their biosurfactant and fungicidal properties, as well as a number of other biological activities. Extracellular Glycolipids of Yeasts gives researchers studying biochemistry of microorganisms and related biologically active compounds a much-needed guide to the basic data that will aid in these increasingly generative pursuits. - Provides a clear overview of the basic data on yeast biosurfactants using a simple survey-style approach - Delivers comprehensive view of biochemistry, biological activity, and practical application of yeasts to aid in their scientific and practical use - Clarifies and simplifies the complex topic of glycolipids, and its often-confusing terminology</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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5,282円
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Extracellular Targeting of Cell Signaling in Cancer Strategies Directed at MET and RON Receptor Tyrosine Kinase Pathways【電子書籍】
楽天Kobo電子書籍ストア
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<p><strong>International experts present innovative therapeutic strategies to treat cancer patients and prevent disease progression</strong></p> <p><em>Extracellular Targeting of Cell Signaling in Cancer</em> highlights innovative therapeutic strategies to treat cancer metastasis and prevent tumor progression. Currently, there are no drugs available to treat or prevent metastatic cancer other than non-selective, toxic chemotherapy. With contributions from an international panel of experts in the field, the book integrates diverse aspects of biochemistry, molecular biology, protein engineering, proteomics, cell biology, pharmacology, biophysics, structural biology, medicinal chemistry and drug development.</p> <p>A large class of proteins called kinases are enzymes required by cancer cells to grow, proliferate, and survive apoptosis (death) by the immune system. Two important kinases are MET and RON which are receptor tyrosine kinases (RTKs) that initiate cell signaling pathways outside the cell surface in response to extracellular ligands (growth factors.) Both kinases are oncogenes which are required by cancer cells to migrate away from the primary tumor, invade surrounding tissue and metastasize. MET and RON reside on both cancer cells and the support cells surrounding the tumor, called the microenvironment. MET and RON are activated by their particular ligands, the growth factors HGF and MSP, respectively. Blocking MET and RON kinase activation and downstream signaling is a promising therapeutic strategy for preventing tumor progression and metastasis. Written for cancer physicians and biologists as well as drug discovery and development teams in both industry and academia, this is the first book of its kind which explores novel approaches to inhibit MET and RON kinases other than traditional small molecule kinase inhibitors. These new strategies target key tumorigenic processes on the outside of the cell, such as growth factor activation by proteases. These unique strategies have promising potential as an improved alternative to kinase inhibitors, chemotherapy, or radiation treatment.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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25,357円
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Extracellular Vesicles as Matrix Messengers EXTRACELLULAR VESICLES AS MATR (Biology of Extracellular Matrix) [ Kirsi Rilla ]
楽天ブックス
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EXTRACELLULAR VESICLES AS MATR Biology of Extracellular Matrix Kirsi Rilla SPRINGER NATURE2024 Hardcover 2024 English ISBN:9783031688102 洋書 Computers & Science(コンピューター&科学) Science
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54,560円
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Cell Biology of Extracellular Matrix【電子書籍】[ Elizabeth D. Hay ]
楽天Kobo電子書籍ストア
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<p>At a recent meeting to discuss the domains of cell biology, I put forth a case for the extracellular matrix, even though my argument ran the risk of falling on deaf ears. After all, the matrix is EXTRAcellular, outside the cells. In this book, however, the authors make a compelling case for the relevance of the matrix to cellular concerns. Not only are numerous cell types, including many epithelia, quite caught up in the business of manufacturing matrix components, but also most of them contain matrix molecules in exoskeletons that are attached to the plasmalemma and that organize or otherwise influence the affairs of the cyto plasm. The idea of this book is to present the extracellular matrix to cell biolo gists of all levels. The authors are active and busy investigators, recognized experts in their fields, but all were enthusiastic about the prospect of writing for this audience. The chapters are not "review" articles in the usual sense, nor are they rehashes of symposium talks; they were written specifically for this book and they present the "state of the art" in engaging style, with ample references to more technical or historical reviews. The book is rich in electron micro graphs and diagrams and for many of the latter, as well as for the design of the cover, we are indebted to Sylvia J. Keene, medical illustrator for the Department of Anatomy at Harvard Medical Scrool. We also owe special thanks to Susan G.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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12,154円
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Ultrastructural Pathology of the Cell and Matrix A Text and Atlas of Physiological and Pathological Alterations in the Fine Structure of Cellular and Extracellular Components【電子書籍】[ Feroze N. Ghadially ]
楽天Kobo電子書籍ストア
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<p>Ultrastructural Pathology of the Cell and Matrix: Third Edition Volume 2 presents a comprehensive examination of the intracellular lesion. It discusses the analysis of pathological tissues using electron microscope. It addresses the experimental procedures made on the cellular level. Some of the topics covered in the book are the structure, distribution, and variations of rod-shaped microtubulated bodies; morphology of intracytoplasmic filaments; melanosome-producing and melanosome-containing cells in tumours; myofilaments in striated muscle; and pathological variations in size, shape, and numbers of microbodies. The intracytoplasmic and intranuclear annulate lamellae are fully covered. An in-depth account of the classification, history, and nomenclature of lysosomes are provided. The morphology and normal variations of melanosomes and anchoring fibrils are completely presented. A chapter is devoted to the endocytotic structures and cell processes. Another section focuses on the classification and nomenclature of fibrous components. The book can provide useful information to cytologists, pathologists, students, and researchers.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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9,934円
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Extracellular Nucleic Acids【電子書籍】
楽天Kobo電子書籍ストア
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<p>Extracellular nucleic acids have recently emerged as important players in the fields of biology and the medical sciences. In the last several years, extracellular nucleic acids have been shown to be involved in not only microbial evolution as genetic elements but also to have structural roles in bacterial communities, such as biofilms. Circulating DNA and RNA have been found in human blood and expected to be useful as non-invasive markers for the diagnosis of several diseases. In addition, extracellular nucleic acids have attracted attention as active modulators of the immune system of higher organisms, including humans. This book covers nearly all of the newly developing fields related to extracellular nucleic acids, including those of basic biology, ecology and the medical sciences, and provides readers with the latest knowledge on them.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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18,231円
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洋書 Paperback, Extracellular Matrix in Development (Biology of Extracellular Matrix)
Glomarket
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*** We ship internationally, so do not use a package forwarding service. We cannot ship to a package forwarding company address because of the Japanese customs regulation. If it is shipped and customs office does not let the package go, we do not make a refund. 【注意事項】 *** 特に注意してください。 *** ・個人ではない法人・団体名義での購入はできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 ・お名前にカタカナが入っている場合法人である可能性が高いため当店システムから自動保留します。カタカナで記載が必要な場合はカタカナ変わりローマ字で記載してください。 ・お名前またはご住所が法人・団体名義(XX株式会社等)、商店名などを含めている場合、または電話番号が個人のものではない場合、税関から法人名義でみなされますのでご注意ください。 ・転送サービス会社への発送もできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 *** ・注文後品切れや価格変動でキャンセルされる場合がございますので予めご了承願います。 ・当店でご購入された商品は、原則として、「個人輸入」としての取り扱いになり、すべてニュージャージからお客様のもとへ直送されます。 ・ご注文後、30営業日以内(通常2~3週間)に配送手続きをいたします。配送作業完了後、2週間程度でのお届けとなります。 ・まれに商品入荷状況や国際情勢、運送、通関事情により、お届けが2ヶ月までかかる場合がありますのでお急ぎの場合は注文をお控えください。 ・個人輸入される商品は、すべてご注文者自身の「個人使用・個人消費」が前提となりますので、ご注文された商品を第三者へ譲渡・転売することは法律で禁止されております。 ・関税・消費税が課税される場合があります。詳細はこちらをご確認下さい。PC販売説明文
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41,781円
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Extracellular Matrix for Tissue Engineering and Biomaterials【電子書籍】
楽天Kobo電子書籍ストア
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<p>This volume provides a state-of-art-report on the new methodologies in tissue engineering and developments in the biomaterials field based on the extracellular matrix-relevant discovery. Extracellular Matrix for Tissue Engineering and Biomaterials opens with an overview of the latest extracellular matrix research and in Part I, focuses on its biology and its role on cell behavior and cell fate relevant for the design of biomimetic surfaces. Part II details issues regarding the strategies currently applied in the research of biologically inspired materials and material systems for the replacement, repair and regeneration of tissues and organs. Part III presents the latest development methods applying knowledge from biology towards nanotechnology, to promote the restoration of the functionality of a living tissue. The book ranges from fundamental biology associated with tissue regeneration for the development of biomimetic approaches to controlling tissue formation, cell function,differentiation and angiogenesis using factors involved in normal tissue development and function. With the breadth and depth of the coverage of this topic, this book will serve as a valuable reference for anyone working in tissue engineering or biomaterials ? from scientists, chemists and biologists through physicists, bioengineers and clinicians.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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18,231円
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Bacterial Extracellular Vesicles Methods and Protocols【電子書籍】
楽天Kobo電子書籍ストア
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<p>This volume details procedures relevant to all disciplines, with specific emphasis on challenging aspects of working with Bacterial Extracellular Vesicle (BEVs). Chapters are divided into four parts focusing on characterization of Bacterial Extracellular Vesicles, assessment of Bacterial Extracellular Vesicle Biological Function In Vitro, preparation and functionalization of therapeutic Bacterial Extracellular Vesicles, and delivery and tracking of Bacterial Extracellular Vesicles In Vivo. Written in the highly successful <em>Methods in Molecular Biology</em> series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.</p> <p>Authoritative and cutting-edge, <em>Bacterial Extracellular Vesicles</em>*: Methods and Protocols* aims to ensure successful results in the further study of this vital field.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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21,878円
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Living alkaline, living happy Restoring the acid-base balance of extracellular matrix for the health of body and mind【電子書籍】[ Andrea Grieco ]
楽天Kobo電子書籍ストア
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<p>The title of this book might somehow sound as if it is related to a work of psychology, but it is actually a book about health. All physical diseases, chronic pain, fibromyalgia, anxiety, depression, diabetes, obesity and overweight have a very close connection with progressive acidification of the body. Health and wellbeing can exist only when a slightly alkaline extracellular matrix (the entirety of the spaces between our cells) exists.</p> <p>Dr. Andrea Grieco is a specialist in Neurology and Nephrology. He has dedicated his entire professional life to the study of Fibromyalgia, and in this book he clearly and thoroughly explains the relationship between acidosis and all body-mind dysfunctions.</p> <p>This book is founded on three pillars: helping suffering people to regain wellbeing and health, sharing the knowledge and experiences regarding the alkalization of the extracellular matrix, and clarifying a subject that is often surrounded by misinformation and statements unsupported by scientific thought.</p> <p>Reading will be like a journey within our organism and its deepest functioning mechanisms, where illnesses begin, but also where our self-healing power and our well-being begins.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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709円
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Extracellular Vesicles From Bench to Bedside【電子書籍】
楽天Kobo電子書籍ストア
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<p>This book aims to provide a comprehensive and systematic understanding of research on extracellular vesicles (EVs). Extracellular vesicles, including exosomes and microvesicles, are nano-sized lipid bilayer encapsulated membranes carrying proteins, lipids, nucleic acids. They are shed by the majority of the cells into the extracellular milieu and present in many biological fluids (blood, urine, saliva, breast milk, cerebrospinal fluid, follicular fluid, semen, lung lavage, and tears). With numerous research publications in recent years, the study of EVs is the emerging field across plenty of disciplines. Many researches and efforts have shown their biogenesis, multiple roles in physiological and pathophysiological processes, and their potential roles as therapeutic agents. The book is organized by outstanding scientists in EV field from the Chinese Society for Extracellular Vesicle (CSEV). It covers the biological basic research of EVs, especially on technologies and methods, as well as the clinical application of EVs as biomarkers for disease diagnosis and therapy.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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26,740円
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The Extracellular Matrix: an Overview【電子書籍】
楽天Kobo電子書籍ストア
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<p>Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling.</p> <p>This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans**,** microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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36,464円
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Anoikis How the Extracellular Matrix Regulates Life-or-Death Decisions【電子書籍】
楽天Kobo電子書籍ストア
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<p>Anoikis is defined broadly as apoptosis that is inhibited by appropriate cell-matrix interactions. Normal and tumor cells vary widely in their sensitivity to anoikis, but, in general, metastatic tumor cells are inevitably anoikis-resistant. In particular, tumor cells that possess a cancer stem cell or mesenchymal phenotype, arising from the oncogenic Epithelial-Mesenchymal Transition (EMT), are transcriptionally re-programmed to resist anoikis. While the anoikis response occurs through the mitochondrial pathway typically found in other apoptotic responses (e.g., DNA damage, death receptors, oxidative stress), the regulation of anoikis by cell-matrix signalling is unique and only partially characterized. The uniqueness of anoikis is: a. regulation by integrins, non-integrin matrix receptors, and the signaling complexes associated with them; b. regulation by metabolic changes occurring in response to attachment/detachment; c. regulation by oncogenes and tumor suppressor genes d. regulation by tumor microenvironment; e. regulation by EMT.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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15,800円
|
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