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Genomics in the Cloud Using Docker, GATK, and WDL in Terra【電子書籍】[ Geraldine A. Van der Auwera ]

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<p>Data in the genomics field is booming. In just a few years, organizations such as the National Institutes of Health (NIH) will host 50+ petabytes???or over 50 million gigabytes???of genomic data, and they???re turning to cloud infrastructure to make that data available to the research community. How do you adapt analysis tools and protocols to access and analyze that volume of data in the cloud?</p> <p>With this practical book, researchers will learn how to work with genomics algorithms using open source tools including the Genome Analysis Toolkit (GATK), Docker, WDL, and Terra. Geraldine Van der Auwera, longtime custodian of the GATK user community, and Brian O???Connor of the UC Santa Cruz Genomics Institute, guide you through the process. You???ll learn by working with real data and genomics algorithms from the field.</p> <p>This book covers:</p> <ul> <li>Essential genomics and computing technology background</li> <li>Basic cloud computing operations</li> <li>Getting started with GATK, plus three major GATK Best Practices pipelines</li> <li>Automating analysis with scripted workflows using WDL and Cromwell</li> <li>Scaling up workflow execution in the cloud, including parallelization and cost optimization</li> <li>Interactive analysis in the cloud using Jupyter notebooks</li> <li>Secure collaboration and computational reproducibility using Terra</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 6,151円

Handbook of Statistical Genomics【電子書籍】

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<p><strong>A timely update of a highly popular handbook on statistical genomics</strong></p> <p>This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as <em>the</em> reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation.</p> <p><em>The Handbook of Statistical Genomics</em> focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research.</p> <ul> <li>Provides much-needed, timely coverage of new developments in this expanding area of study</li> <li>Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics</li> <li>Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics</li> <li>Extensive coverage of human genetic epidemiology, including ethical aspects</li> <li>Edited by one of the leading experts in the field along with rising stars as his co-editors</li> <li>Chapter authors are world-renowned experts in the field, and newly emerging leaders.</li> </ul> <p><em>The Handbook of Statistical Genomics</em> is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 43,805円

Thompson & Thompson Genetics and Genomics in Medicine E-Book Thompson & Thompson Genetics and Genomics in Medicine E-Book【電子書籍】

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<p>First published in 1966, <em>Thompson and Thompson Genetics and Genomics in Medicine</em> has become an essential textbook for medical students, genetic counseling students, students in laboratory medicine, and more advanced trainees. With its focus on fundamental principles in human genetics and genomics and their application to medicine, the book has served many as a well-thumbed resource they return to over and over.</p> <p>Such students can continue to depend on this valuable text, joining those in newer fields of genome data analysis for all they need to know about genetics and genomics throughout their basic science training, clinical placements and beyond. Coverage includes new discoveriesーsuch as the functional roles of non-coding RNAs, chromatin regulation and epigeneticsーlatest technologies, and new diagnoses they are enabling.</p> <p>Under an expanded title, this ninth edition has been completely revised by a new editorial team overseeing a large cadre of contributing authors. Support groups have also assisted to update illustrations featuring beautiful images of those living with genetic conditions.</p> <ul> <li> <p>Comprehensive coverage of: genomes in biology and medicine; copy number and structural genomic variation; novel discoveries; latest technology; and new genetic diagnoses</p> </li> <li></li> <li> <p>Over 40 clinical case studies, capturing the latest challenges of variable expression, pleiotropy, and complex disorders through new diagnostic strategies</p> </li> <li></li> <li> <p>Full-color text, illustrations, updated line diagrams, and clinical photos</p> </li> <li></li> <li> <p>End-of-chapter questions and comprehensive answers to challenge the reader to consolidate the material into practice and prepare for examinations</p> </li> <li></li> <li> <p>USMLE-style and multiple choice questions</p> </li> <li> <p>Updated and new clinical cases, supported with photography by the not-for-profit organization, <em>Positive Exposure</em></p> </li> <li></li> <li> <p>New content on growing role of sequencing and novel functional assays in diagnosis and screening of genetic conditions</p> </li> <li></li> <li> <p>New chapter on Epigenetics</p> </li> <li></li> <li> <p>Clearer and more precise terminology, in response to contemporary and evolving guidelines</p> </li> <li></li> <li> <p>New sections describing the use (and need for) genetic information from diverse populations, including unique indigenous and founder populations, for diagnosis and management.</p> </li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 7,477円

Genomics of Rare Diseases Understanding Disease Genetics Using Genomic Approaches【電子書籍】

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<p><em>Genomics of Rare Diseases: Understanding Disease Genetics Using Genomic Approaches</em>, a new volume in the <em>Translational and Applied Genomics</em> series, offers readers a broad understanding of current knowledge on rare diseases through a genomics lens. This clear understanding of the latest molecular and genomic technologies used to elucidate the molecular causes of more than 5,000 genetic disorders brings readers closer to unraveling many more that remain undefined and undiscovered. The challenges associated with performing rare disease research are also discussed, as well as the opportunities that the study of these disorders provides for improving our understanding of disease architecture and pathophysiology.</p> <p>Leading chapter authors in the field discuss approaches such as karyotyping and genomic sequencing for the better diagnosis and treatment of conditions including recessive diseases, dominant and X-linked disorders, de novo mutations, sporadic disorders and mosaicism.</p> <ul> <li>Compiles applied case studies and methodologies, enabling researchers, clinicians and healthcare providers to effectively classify DNA variants associated with disease and patient phenotypes</li> <li>Discusses the main challenges in studying the genetics of rare diseases through genomic approaches and possible or ongoing solutions</li> <li>Explores opportunities for novel therapeutics</li> <li>Features chapter contributions from leading researchers and clinicians</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 16,313円

Genetics/Genomics Nursing Scope and Standards of Practice【電子書籍】[ American Nurses Association ]

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<p>Completely updated by genetics/genomics nurses for genetics/genomics nurses. The first best resource for the RN or APRN genetics/genomics nurse at any level and in any setting. Essential for all involved in this nursing practice specialty now and throughout this decade. Genetics/genomics nursing practice and care focuses on the actual and potential impact of genetic and genomic influences on health. These nurses advise and educate clients and families on such influences that might impact their health, identify and manage physiologic responses. The goals of their nursing interventions: to optimize health, reduce health risks, treat disease, and promote wellness. Their research and evidence-based practice also includes interprofessional collegiality and collaboration with other genetics/genomics professionals and other healthcare professionals to provide quality patient care. A workgroup of genetics/genomics nurse experts, convened by ISONG and ANA, completely updated and expanded the previous edition. With input from nurses nationwide, their revision addressed and incorporated ongoing and anticipated changes in genetics/genomics nursing as well as in nursing and health care in general. The revised scope of genetics/genomics nursing practiceーthe who, what, where, when, why, and how of practiceーsets the context for understanding and using the standards: the underlying assumptions, characteristics, environments and settings, education and training requirements, key issues and trends, and ethical and conceptual bases of genetics/genomics nursing. The updated 16 standards frame any evaluation of the outcomes and goals of, and measure the accountabilities for, general, graduate-level prepared, and advanced practice genetics/genomics nurses. By meeting each standard's competencies, these nurses can demonstrate compliance with that standard. A foundational volume primarily for those directly involved with genetics/genomics nursing practice, education, and research, other nurses and allied healthcare providers, researchers, and scholars will find value in its content. About ANA's Specialty Nursing Standards Since the late 1990s, ANA has partnered with other nursing organizations to establish a formal process for recognition of specialty areas of nursing practice. This includes the criteria for approving the specialty itself and the scope statement, and an acknowledgment by ANA of the standards of practice for that specialty. Because of the significant changes in the evolving nursing and healthcare environments, ANA's approval of specialty nursing scope statements and its acknowledgment of specialty standards of practice remain valid for five years, starting from the publication date of the documents. The standards in this publication are based on language from ANA's Nursing: Scope and Standards of Practice, Second Edition, a helpful supplement to this specialty text, which in turn is of optimal use with two complementary ANA texts: Nursing's Social Policy Statement and Guide to the Code of Ethics for Nurses. Together, these three books help guide nursing practice, thinking, and decision-making. The set is proving useful as a professional reference, classroom textbook, in-service training guide, and credentialing exam resource.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 3,872円

Bioinformatics and Functional Genomics【電子書籍】[ Jonathan Pevsner ]

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<p><strong>The bestselling introduction to bioinformatics and genomics ? now in its <em>third edition</em></strong></p> <p>Widely received in its previous editions, <em>Bioinformatics and Functional Genomics</em> offers the most broad-based introduction to this explosive new discipline. Now in a thoroughly updated and expanded third edition, it continues to be the go-to source for students and professionals involved in biomedical research.</p> <p>This book provides up-to-the-minute coverage of the fields of bioinformatics and genomics. Features new to this edition include:</p> <ul> <li>Extensive revisions and a slight reorder of chapters for a more effective organization</li> <li>A brand new chapter on next-generation sequencing</li> <li>An expanded companion website, also updated as and when new information becomes available</li> <li>Greater emphasis on a computational approach, with clear guidance of how software tools work and introductions to the use of command-line tools such as software for next-generation sequence analysis, the R programming language, and NCBI search utilities</li> </ul> <p>The book is complemented by lavish illustrations and more than 500 figures and tables - many newly-created for the third edition to enhance clarity and understanding. Each chapter includes learning objectives, a problem set, pitfalls section, boxes explaining key techniques and mathematics/statistics principles, a summary, recommended reading, and a list of freely available software. Readers may visit a related Web page for supplemental information such as PowerPoints and audiovisual files of lectures, and videocasts of how to perform many basic operations: www.wiley.com/go/pevsnerbioinformatics.</p> <p><em>Bioinformatics and Functional Genomics</em>, Third Edition serves as an excellent single-source textbook for advanced undergraduate and beginning graduate-level courses in the biological sciences and computer sciences. It is also an indispensable resource for biologists in a broad variety of disciplines who use the tools of bioinformatics and genomics to study particular research problems; bioinformaticists and computer scientists who develop computer algorithms and databases; and medical researchers and clinicians who want to understand the genomic basis of viral, bacterial, parasitic, or other diseases.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 17,015円

Computational Genomics with R【電子書籍】[ Altuna Akalin ]

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<p>Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the code presented. As the field of computational genomics is interdisciplinary, it requires different starting points for people with different backgrounds. For example, a biologist might skip sections on basic genome biology and start with R programming, whereas a computer scientist might want to start with genome biology.</p> <p>After reading:</p> <ul> <li>You will have the basics of R and be able to dive right into specialized uses of R for computational genomics such as using Bioconductor packages.</li> <li>You will be familiar with statistics, supervised and unsupervised learning techniques that are important in data modeling, and exploratory analysis of high-dimensional data.</li> <li>You will understand genomic intervals and operations on them that are used for tasks such as aligned read counting and genomic feature annotation.</li> <li>You will know the basics of processing and quality checking high-throughput sequencing data.</li> <li>You will be able to do sequence analysis, such as calculating GC content for parts of a genome or finding transcription factor binding sites.</li> <li>You will know about visualization techniques used in genomics, such as heatmaps, meta-gene plots, and genomic track visualization.</li> <li>You will be familiar with analysis of different high-throughput sequencing data sets, such as RNA-seq, ChIP-seq, and BS-seq.</li> <li>You will know basic techniques for integrating and interpreting multi-omics datasets.</li> </ul> <p>Altuna Akalin is a group leader and head of the Bioinformatics and Omics Data Science Platform at the Berlin Institute of Medical Systems Biology, Max Delbr?ck Center, Berlin. He has been developing computational methods for analyzing and integrating large-scale genomics data sets since 2002. He has published an extensive body of work in this area. The framework for this book grew out of the yearly computational genomics courses he has been organizing and teaching since 2015.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 7,877円

Routledge Handbook of Genomics, Health and Society【電子書籍】

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<p>The <em>Handbook</em> provides an essential resource at the interface of Genomics, Health and Society, and forms a crucial research tool for both new students and established scholars across biomedicine and social sciences. Building from and extending the first <em>Routledge Handbook of Genetics and Society</em>, the book offers a comprehensive introduction to pivotal themes within the field, an overview of the current state of the art knowledge on genomics, science and society, and an outline of emerging areas of research.</p> <p>Key themes addressed include the way genomic based DNA technologies have become incorporated into diverse arenas of clinical practice and research whilst also extending beyond the clinic; the role of genomics in contemporary ‘bioeconomies’; how challenges in the governance of medical genomics can both reconfigure and stabilise regulatory processes and jurisdictional boundaries; how questions of diversity and justice are situated across different national and transnational terrains of genomic research; and how genomics informs ? and is shaped by ? developments in fields such as epigenetics, synthetic biology, stem cell, microbial and animal model research.</p> <p>Chapters 13 and 28 of this book are freely available as downloadable Open Access PDFs at www.taylorfrancis.com, under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 4.0 license.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 8,278円

A New Kind of Computational Biology Cellular Automata Based Models for Genomics and Proteomics【電子書籍】[ Parimal Pal Chaudhuri ]

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<p>This book reflects more than three decades of research on Cellular Automata (CA), and nearly a decade of work on the application of CA to model biological strings, which forms the foundation of 'A New Kind of Computational Biology' pioneered by the start-up, CARLBio. After a brief introduction on Cellular Automata (CA) theory and functional biology, it reports on the modeling of basic biological strings with CA, starting with the basic nucleotides leading to codon and anti-codon CA models. It derives a more involved CA model of DNA, RNA, the entire translation process for amino acid formation and the evolution of protein to its unique structure and function. In subsequent chapters the interaction of Proteins with other bio-molecules is also modeled. The only prior knowledge assumed necessary is an undergraduate knowledge of computer programming and biology.</p> <p>The book adopts a hands-on, “do-it-yourself” approach to enable readers to apply the method provided to derive the CArules and comprehend how these are related to the physical ‘rules’ observed in biology. In a single framework, the authors have presented two branches of science ? Computation and Biology. Instead of rigorous molecular dynamics modeling, which the authors describe as a Bottoms-Up model, or relying on the Top-Down new age Artificial Intelligence (AI) and Machine Language (ML) that depends on extensive availability of quality data, this book takes the best from both the Top-Down and Bottoms-up approaches and establishes how the behavior of complex molecules is represented in CA. The CA rules are derived from the basic knowledge of molecular interaction and construction observed in biological world but mapped to a few subset of known results to derive and predict results.</p> <p>This book is useful for students, researchers and industry practitioners who want to explore modeling and simulation of the physical world complex systems from a different perspective. It raises the inevitable the question ? ‘Are life and the universe nothing but a collection of continuous systems processing information’.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 6,076円

(出版社)Cold Spring Harbor Laboratory Press Methods in Yeast Genetics and Genomics, 2015 Edition 1冊 978-1-62182-134-2

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(出版社)Cold Spring Harbor Laboratory Press Methods in Yeast Genetics and Genomics, 2015 Edition 1冊●著者:Dunham, Maitreya●編者:Dunham, Maitreya J./Gartenberg, Marc R.●シリーズ名:Cold Spring Harbor Laboratory Course Manual●和文:酵母遺伝子とゲノム実験マニュアル 2015年版●頁数他:256 p.●装丁:Hard●出版社:Cold Spring Harbor Laboratory Press●発行日:2015/10/1 18,709円

Functional Genomics and Evolution of Photosynthetic Systems【電子書籍】

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<p>New possibilities have been brought about by the stunning number of genomic sequences becoming available for photosynthetic organisms. This new world of whole genome sequence data spans the phyla from photosynthetic microbes to algae to higher plants. These whole genome projects are intrinsically interesting, but also inform the variety of other molecular sequence databases including the recent 'meta-genomic' sequencing efforts that analyze entire communities of organisms. As impressive as they are, are obviously only the beginning of the effort to decipher the biological meaning encoded within them. This book aims to highlight progress in this direction. This book aims toward a genome-level understanding of the structure, function, and evolution of photosynthetic systems and the advantages accrued from the availability of phyletically diverse sets of gene sequences for the major components of the photosynthetic apparatus. While not meant to be fully comprehensive in terms of the topics covered, it does provide detailed views of specific cases and thereby illustrates important new directions that are being taken in this fast-moving fieldーa field that involves the integration of bioinformatics, molecular biology, physiology, and ecology.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 24,309円

Genetics and Genomics of Cotton【電子書籍】

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<p>A few members of the Gossypium (cotton) genus are cultivated for the production of elongated single-celled fibers valued worldwide at about $20 billion annually at the farm gate, and which sustain one of the world’s largest industries (textiles) with an annual worldwide economic impact of about $500 billion. In a number of ways, cotton production and the textile industry are closely tied to petrochemical usage. At a practical level, cotton genomics offers both bio-based carbon sequestration alternatives to petrochemical use, and improved sustainability of crop production.</p> <p>The Gossypium (cotton) also genus presents novel opportunities to advance our understanding of the natural world and its organic evolution. In particular, the evolution of cultivated cottons from their wild ancestors has involved a fascinating series of events that offer scientists the opportunity to dissect the evolution of a novel organ, the ‘lint fiber’, and also to unravel the consequences of polyploidy, both for the generation of biodiversity and for crop productivity.</p> <p>In this book, advances of the past decade will be summarized and synthesized to elucidate the current state of knowledge of the structure, function, and evolution of the Gossypium genome, and progress in the application of this knowledge to cotton improvement. This book will address five broad topics. First, as a backdrop for all studies of the genus, it is important to understand the naturally-occurring diversity in the genus, its organization and distribution, and its evolutionary history. Of special importance is the formation of a single polyploid from two (among 8) diploid genome types, the radiation of this polyploid, and the domestication and improvement of two (among 5 extant) polyploid species.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 24,309円

Functional Genomics in Aquaculture【電子書籍】[ Marco Saroglia ]

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<p>Genomics has revolutionized biological research over the course of the last two decades. Genome maps of key agricultural species have offered increased understanding of the structure, organization, and evolution of animal genomes. Building upon this foundation, researchers are now emphasizing research on genome function. Published with the <strong>World Aquaculture Society</strong>, <em>Functional Genomics in Aquaculture</em> looks at the advances in this field as they directly relate to key traits and species in aquaculture production.</p> <p><em>Functional Genomics in Aquaculture</em> opens with two chapters that provide a useful general introduction to the field of functional genomics. The second section of the book focuses on key production traits such as growth, development, reproduction, nutrition, and physiological response to stress and diseases. The final five chapters focus on a variety of key aquaculture species. Examples looking at our understanding of the functional genomes of salmonids, Mediterranean sea bass, Atlantic cod, catfish, shrimp, and molluscs, are included in the book.</p> <p>Providing valuable insights and discoveries into the functional genomes of finfish and shellfish species, <em>Functional Genomics in Aquaculture</em>, will be an invaluable resource to researchers and professionals in aquaculture, genetics, and animal science.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 28,046円

Genomics: commercial opportunities from a scientific revolution【電子書籍】

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<p>This title covers topical and unexplored issues relating to the commercial outcome of the genetic revolution which will be of great interest to both academia and industry. The book discusses whether the availability of genome sequence information will yie</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 8,252円

Oil Crop Genomics【電子書籍】

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<p>Plants are an important source of fats and oils, which are essential for the human diet. In recent years, genomics of oil biosynthesis in plants have attracted great interest, especially in high oil-bearing plants, such as sesame, olive, sunflower, and palm. Considering that, genome sequencing projects of these plants have been undertaken with the help of advanced genomics tools such as next generation sequencing. Several genome sequencing projects of oil crops are in progress and many others are en route. In addition to genome information, advanced genomics approaches are discussed such as transcriptomics, genomics-assisted breeding, genome-wide association study (GWAS), genotyping by sequencing (GBS), and CRISPR. These have all improved our understanding of the oil biosynthesis mechanism and breeding strategies for oil production.</p> <p>There is, however, no book that covers the genomes and genomics of oil crops. For this reason, in this volume we collected the most recent knowledge of oil crop genomics for researchers who study oil crop genomes, genomics, biotechnology, pharmacology, and medicine. This book covers all genome-sequenced oil crops as well as the plants producing important oil metabolites. Throughout this book, the latest genomics developments and discoveries are highlighted as well as open problems and future challenges in oil crop genomics. In doing so, we have covered the state-of-the-art of developments and trends of oil crop genomics.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 21,878円

Bacterial Genetics and Genomics【電子書籍】[ Lori A.S. Snyder ]

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<p>Our understanding of bacterial genetics has progressed as the genomics field has advanced. Genetics and genomics complement and influence each other; they are inseparable. Under the novel insights from genetics and genomics, once-believed borders in biology start to fade: biological knowledge of the bacterial world is being viewed under a new light and concepts are being redefined. Species are difficult to delimit and relationships within and between groups of bacteria ? the whole concept of a tree of life ? is hotly debated when dealing with bacteria. The DNA within bacterial cells contains a variety of features and signals that influence the diversity of the microbial world. This text assumes readers have some knowledge of genetics and microbiology but acknowledges that it can be varied. Therefore, the book includes all of the information that readers need to know in order to understand the more advanced material in the book.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 12,284円

Banana: Genomics and Transgenic Approaches for Genetic Improvement【電子書籍】

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<p>Bananas and plantains are among the most important food and cash crops in the world. They are cultivated in more than 135 countries, across the tropics and subtropics, with an annual global production of ca. 130 million metric tonnes. Though bananas are one of the most important components of food security in many developing countries, banana production is threatened by both abiotic and biotic stresses. These include a wide range of diseases and pests, such as bunchy top virus, burrowing nematodes, black Sigatoka or black leaf streak, Fusarium wilt, etc.</p> <p>In recent years, considerable progress has been made and several biotechnological and genomic tools have been employed to help understand and unravel the mysterious banana genome. Molecular and genomic studies have helped to decipher the Musa genome and its evolution. Genetic linkage map and whole genome sequencing of both Musa acuminata and Musa balbisiana (progenitors of cultivated banana) have completely changedthe way of thinking and the approach on banana crop improvement. Whole-genome sequencing has helped to improve the selection of quantitative traits such as yield, as well as the selection of optimal parents for developing required hybrids in breeding programs. Gene isolation and the analysis of mutants have helped in the characterization of genes of agronomic value and the associated regulatory sequences. With the advent of molecular markers and new statistical tools, it is now possible to measure the diversity, identify genes and useful alleles linked to important agronomic traits. Further these alleles can be incorporated into cultivars through marker assisted selection or through transgenic approach. Transgenic approaches are potential tools for direct transfer of these genes into popular cultivars, which are generally not amenable for conventional breeding techniques, in specific with crops such as bananas which are sterile, triploid and heterozygous thereby making itdifficult to reconstruct the recurrent genotypes in banana. Transgenic techniques thus have helped overcome the difficulty of working with sterile, triploid banana crop. In the last five years, enormous amount of new information and techniques have been generated for banana. A comprehensive book entitled “Banana: Genomics and Transgenic Approaches for Genetic improvement” on banana genomics, latest transgenic technologies and tools available for improved crop development in banana will address all these requirements.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 18,231円

Translational Research in Genetics and Genomics【電子書籍】[ Moyra Smith, M.D. ]

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<p>In this new book, noted geneticist and veteran OUP author, Moyra Smith, present a comprehensive critical review of the translation of genetic and genomic research into health care. Dr. Smith's motivation for writing is driven by the gap that exists between the rather amazing discoveries in medical genetics and genomics at basic science levels and the translation to disease management in single gene disorders, specific genetic syndromes, and complex genetic diseases. She also examines information technology in genetic medicine, sociocultural factors that impact provision of medical care, and medical education issues with regard to translational genetics in order to help prepare a work force that is better able to utilize evidence-based medicine and to accomodate the rapid changes in genetic and genomic health care.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 11,916円

Comparative Genomics 21st International Conference, RECOMB-CG 2024, Boston, MA, USA, April 27?28, 2024, Proceedings【電子書籍】

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<p>This book constitutes the proceedings of the 21st International Conference on Comparative Genomics, RECOMB-CG 2024, which was held in Boston, MA, USA, during April 27?28, 2024.</p> <p>The 13 full papers presented in this book were carefully reviewed and selected from 21 submissions. The papers are divided into the following topical sections: phylogenetic networks; homology and phylogenetic reconstruction; tools for evolution reconstruction; genome rearrangements; and genome evolution.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 7,049円

Cancer Genomics for the Clinician【電子書籍】

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<p><em><strong>Cancer Genomics for the Clinician</strong></em> is a practical guide to cancer genomics and its application to cancer diagnosis and care. The book begins with a brief overview of the various types of genetic alterations that are encountered in cancer, followed by accessible and applicable information on next generation sequencing technology and bioinformatics; tumor heterogeneity; whole genome, exome, and transcriptome sequencing; epigenomics; and data analysis and interpretation. Each chapter provides essential explanations of concepts, terminology, and methods. Also included are tips for interpreting and analyzing molecular data, as well as a discussion of molecular predictors for targeted therapies covering hematologic malignancies and solid tumors. The final chapter explains the use of FDA-approved genomic-based targeted therapies for breast cancer, lung cancer, sarcomas, gastrointestinal cancers, urologic cancers, head and neck cancer, thyroid cancer, and many more.</p> <p>Assembled in an accessible format specifically designed for the non-expert, this book provides the clinical oncologist, early career practitioner, and trainee with an essential understanding of the molecular and genetic basis of cancer and the clinical aspects that have led to advancements in diagnosis and treatment. With this resource, physicians and trainees will increase their breadth of knowledge and be better equipped to educate patients and families who want to know more about their genetic predispositions to cancer and the targeted therapies that could be considered and prescribed.</p> <p><strong>Key Features:</strong></p> <ul> <li>Describes how cancer genomics and next generation sequencing informs cancer screening, risk factors, therapeutic options, and clinical management across cancer types</li> <li>Explains what mutations are, what tests are needed, and how to interpret the results</li> <li>Provides information on FDA-approved targeted therapies that are being used in the clinic</li> <li>Covers different sequencing platforms and technologies and how they perform in research settings</li> <li>Includes access to the fully searchable eBook</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 6,809円

Potato Improvement in the Post-Genomics Era【電子書籍】[ Jagesh Tiwari ]

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<p>The book delves into post-genomics advances in potato improvement since the potato genome sequencing in 2011. It includes recent developments in the field of potato genetic resources, genes and SNP markers discovery, and the progress in next-generation breeding applying various omics technologies and modern sequencing tools. It covers cutting-edge technologies in potato - a global perspective, genome sequencing and resequencing of various cultivated and wild species, potato germplasm management and characterization, prebreeding genomics, genome mapping and gene cloning, markers discovery, marker-assisted selection, transgenics, microRNAs, transcriptomics, proteomics, metabolomics, phenomics, next-generation potato breeding technologies including genome editing and genomic selection and bioinformatics applications in the post-genomics era in potato. As genome editing and genomic selection have become emerging tools in crop improvement including potato, several research works have been demonstrated and applied world over. This book concentrates on genomics-aided characterization of germplasm and markers discovery to accelerate potato breeding. Further, various omics technologies strengthen our understanding on<br /> discovery of new genes/proteins/metabolites and key traits based on high-throughput phenotyping involved in various biotic and abiotic stresses in potato crop. The book is a useful source of information related to genomics-led research and development of this crop. It will serve as a valuable resource for potato researchers working in the area of molecular biology and would be beneficial for college students, PhD scholars, scientists, academicians, farmers and policy makers.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 8,945円

Literature, Science, and Public Policy From Darwin to Genomics【電子書籍】[ Jay Clayton ]

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<p>Literature, Science, and Public Policy shows how literature can influence public policy concerning scientific controversies in genetics and other areas. Literature brings unique insights to issues involving cloning, GMOs, gene editing, and more by dramatizing their full human complexity. Literature's value for public policy is demonstrated by striking examples that range from the literary response to evolution in the Victorian era through the modern synthesis of evolution and genetics in the mid-twentieth century to present-day genomics. Outlining practical steps for humanists who want to help shape public policy, this book offers vivid readings of novels by H. G. Wells, H. Rider Haggard, Aldous Huxley, Robert Heinlein, Octavia Butler, Samuel R. Delany, David Mitchell, Margaret Atwood, Ian McEwan, Kazuo Ishiguro, Gary Shteyngart, and others that illustrate the important insights that literary studies can bring to debates about science and society. This title is also available as Open Access on Cambridge Core.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 11,750円

Introduction to Evolutionary Genomics【電子書籍】[ Naruya Saitou ]

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<p>This authoritative textbook/reference presents a comprehensive introduction to the field of evolutionary genomics. The opening chapters describe the fundamental concepts in molecular biology and genome evolution for readers without any prior background in this area. This is followed by a detailed examination of genome evolution in various different groups of organisms. The text then concludes with a review of practical methods essential to researchers in the field.</p> <p>This updated and revised new edition also features historical perspectives on contributions to evolutionary genomics from related fields such as molecular evolution, genetics, and numerical taxonomy.</p> <p>Topics and features: introduces the basics of molecular biology, covering protein structure and diversity, as well as DNA replication, transcription, and translation; examines the phylogenetic relationships of DNA sequences, and the processes of mutation, neutral evolution, and natural selection; presents a briefevolutionary history of life, surveying the key features of the genomes of prokaryotes, eukaryotes, viruses and phages, vertebrates, and humans; reviews the various biological “omic” databases, and discusses the analysis of homologous nucleotide and amino acid sequences; provides an overview of the experimental sequencing of genomes and transcriptomes, and the construction of phylogenetic trees; describes methods for estimating of evolutionary distances, and performing studies of population genetics; supplies additional supporting material at an associated website.</p> <p>Serving as an indispensable textbook for graduate and advanced undergraduate courses on evolutionary genomics, this accessible overview will also prove invaluable to researchers from both computer science and the biological sciences seeking a primer on the field.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 7,292円

Avian Genomics in Ecology and Evolution From the Lab into the Wild【電子書籍】

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<p>Birds catch the public imagination like no other group of animals; in addition, birders are perhaps the largest non-professional naturalist community. Genomics and associated bioinformatics have revolutionised daily life in just a few decades. At the same time, this development has facilitated the application of genomics technology to ecological and evolutionary studies, including biodiversity and conservation at all levels.</p> <p>This book reveals how the exciting toolbox of genomics offers new opportunities in all areas of avian biology. It presents contributions from prominent experts at the intersection of avian biology and genomics, and offers an ideal introduction to the world of genomics for students, biologists and bird enthusiasts alike. The book begins with a historical perspective on how genomic technology was adopted by bird ecology and evolution research groups. This led, as the book explains, to a revised understanding of avian evolution, with exciting consequences for biodiversity research as a whole. Lastly, these impacts are illustrated using seminal examples and the latest discoveries from avian biology laboratories around the world.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 19,447円

Comparative Genomics 16th International Conference, RECOMB-CG 2018, Magog-Orford, QC, Canada, October 9-12, 2018, Proceedings【電子書籍】

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<p>This book constitutes the proceedings of the 16th International Conference on Comparative Genomics, RECOMB-CG 2018, held in Magog-Orford, QC, Canada, in October 2018.<br /> The 18 full papers presented were carefully reviewed and selected from 29 submissions. The papers cover topics such as: genome rearrangements; genome sequencing; applied comparative genomics; reconciliation and coalescence; and phylogenetics.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 6,076円

Alien Introgression in Wheat Cytogenetics, Molecular Biology, and Genomics【電子書籍】

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<p>This book provides an overview of the latest advancements in the field of alien introgression in wheat. The discovery and wide application of molecular genetic techniques including molecular markers, in situ hybridization, and genomics has led to a surge in interspecific and intergeneric hybridization in recent decades. The work begins with the taxonomy of cereals, especially of those species which are potential gene sources for wheat improvement. The text then goes on to cover the origin of wheat, breeding in connection with alien introgressions, and the problems of producing intergeneric hybrids and backcross derivatives. These problems can include crossability, sterility, and unequal chromosome transmission. The work then covers alien introgressions according to the related species used, as well as new results in the field of genomics of wild wheat relatives and introgressions.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 18,231円

Genomics in the AWS Cloud: Analyzing Genetic Code Using Amazon Web Services GENOMICS IN THE AWS CLOUD [ Catherine Vacher ]

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GENOMICS IN THE AWS CLOUD Catherine Vacher David Wall SYBEX INC2023 Paperback English ISBN:9781119573371 洋書 Computers & Science(コンピューター&科学) Science 7,920円

洋書 Paperback, A Holistic Approach to Rice Research and Genetic Engineering (Rice Genomics, 1)

Glomarket
*** We ship internationally, so do not use a package forwarding service. We cannot ship to a package forwarding company address because of the Japanese customs regulation. If it is shipped and customs office does not let the package go, we do not make a refund. 【注意事項】 *** 特に注意してください。 *** ・個人ではない法人・団体名義での購入はできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 ・お名前にカタカナが入っている場合法人である可能性が高いため当店システムから自動保留します。カタカナで記載が必要な場合はカタカナ変わりローマ字で記載してください。 ・お名前またはご住所が法人・団体名義(XX株式会社等)、商店名などを含めている場合、または電話番号が個人のものではない場合、税関から法人名義でみなされますのでご注意ください。 ・転送サービス会社への発送もできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 *** ・注文後品切れや価格変動でキャンセルされる場合がございますので予めご了承願います。 ・当店でご購入された商品は、原則として、「個人輸入」としての取り扱いになり、すべてニュージャージからお客様のもとへ直送されます。 ・ご注文後、30営業日以内(通常2~3週間)に配送手続きをいたします。配送作業完了後、2週間程度でのお届けとなります。 ・まれに商品入荷状況や国際情勢、運送、通関事情により、お届けが2ヶ月までかかる場合がありますのでお急ぎの場合は注文をお控えください。 ・個人輸入される商品は、すべてご注文者自身の「個人使用・個人消費」が前提となりますので、ご注文された商品を第三者へ譲渡・転売することは法律で禁止されております。 ・関税・消費税が課税される場合があります。詳細はこちらをご確認下さい。PC販売説明文 9,934円

The Genome Factor What the Social Genomics Revolution Reveals about Ourselves, Our History, and the Future【電子書籍】[ Dalton Conley ]

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<p><strong>How genomics is revolutionizing the social sciences</strong></p> <p>For a century, social scientists have avoided genetics like the plague. But the nature-nurture wars are over. In the past decade, a small but intrepid group of economists, political scientists, and sociologists have harnessed the genomics revolution to paint a more complete picture of human social life than ever before. <em>The Genome Factor</em> describes the latest astonishing discoveries being made at the scientific frontier where genomics and the social sciences intersect.</p> <p><em>The Genome Factor</em> reveals that there are real genetic differences by racial ancestryーbut ones that don't conform to what we call black, white, or Latino. Genes explain a significant share of who gets ahead in society and who does not, but instead of giving rise to a genotocracy, genes often act as engines of mobility that counter social disadvantage. An increasing number of us are marrying partners with similar education levels as ourselves, but genetically speaking, humans are mixing it up more than ever before with respect to mating and reproduction. These are just a few of the many findings presented in this illuminating and entertaining book, which also tackles controversial topics such as genetically personalized education and the future of reproduction in a world where more and more of us are taking advantage of cheap genotyping services like 23andMe to find out what our genes may hold in store for ourselves and our children.</p> <p><em>The Genome Factor</em> shows how genomics is transforming the social sciencesーand how social scientists are integrating both nature and nurture into a unified, comprehensive understanding of human behavior at both the individual and society-wide levels.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 2,452円

Cardiovascular Genetics and Genomics Principles and Clinical Practice【電子書籍】

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<p>This title reflects the exponential growth in the knowledge and information on this subject and defines the extensive clinical translation of cardiovascular genetics and genomics in clinical practice. This concise, clinically oriented text is targeted at a broad range of clinicians who manage patients and families with a wide range of heterogeneous inherited cardiovascular conditions.</p> <p><em>Cardiovascular Genetics and Genomics: Principles and Clinical Practice</em> includes a concise and clear account on selected topics written by a team of leading experts on clinical cardiovascular genetics. Each chapter include key information to assist the clinician and case histories have been incorporated to reflect contemporary practice in clinical cardiovascular genetics and genomics. Therefore this will be of key importance to all professionals working in the discipline, from clinicians and trainees in cardiology, cardiac surgery, electrophysiology, immunology through geneticists, nursing staff and those involved in precision medicine.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 26,619円