Heterocycles
 
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Microwave-Induced Synthesis of Aromatic Heterocycles【電子書籍】[ Abdul Rauf ]

楽天Kobo電子書籍ストア
<p>For more than a century, heterocycles have played a crucial role in the biological and industrial development of society, becoming one of the most researched areas within organic chemistry.</p> <p>The first chapter of <em>Microwave-Induced Synthesis of Aromatic Heterocycles</em> is based on microwave theory, the latest developments in instrumentation technology, and the various microwave technologies used for synthesis. The remainder of the chapters are divided into two sections. Section A deals with the five-membered heterocycles (pyrazoles, isoxazoles, triazoles, oxadiazoles, thiazoles, imidazoles, oxazoles, oxazolines etc.) and in Section B, various six-membered heterocycles (triazines, benzoxazoles, benzimidazoles, benzothiazoles) are presented. Both sections contain a detailed, recent literature review of microwave assisted synthesis and its applicability to various aromatic heterocyclics.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 6,072円

Synthesis of 6- and 7-Membered Heterocycles The Role of DMF【電子書籍】[ Navjeet Kaur, BSc; MSc ]

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<p><em>Synthesis of Six- and Seven-Membered Heterocycles: The Role of DMF and its Synthesis</em> compares different synthetic approaches using DMF, including the advantages and disadvantages of those reactions, green methods, and the sustainability of reported synthetic methodologies, especially the microwave methods. The book presents several methodologies for the synthesis of six- and seven-membered heterocyclic compounds using dimethylformamide. Users will find the most up-to-date information in this fast-moving field which can be particularly challenging. With DMF drawing the attention of synthetic organic chemists, this book will help readers understand further developments in the uses of dimethylformamide beyond just its use as a polar solvent.</p> <p>As it can be expected that the use of dimethylformamide as a precursor will continue to grow in organic synthesis with new applications in sustainable and green chemistry, this book provides an ideal primer on the topics covered.</p> <ul> <li>Compares different methods, reagents, reaction conditions, advantages and disadvantages</li> <li>Discusses and compares different methodologies with green techniques</li> <li>Includes reaction schemes, reaction mechanisms and the structure of reactive intermediates</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 19,773円

Vicinal Diaryl Substituted Heterocycles A Gold Mine for the Discovery of Novel Therapeutic Agents【電子書籍】

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<p><em>Vicinal Diaryl-Substituted Heterocycles: A Gold Mine for the Discovery of Novel Therapeutic Agents</em> draws together all of the key information about these compounds in one place for the first time. Following an informative overview of the importance of these structures to the discovery of potential therapeutic agents, the text goes on to outline the main compound types, with each chapter focusing on the activities of a different structure. Designed to support researchers by consolidating this important information in a single, practical guide, the authors hope to encourage further advancement and development in the discovery of novel therapeutic agents.</p> <p>As flexible building blocks for the production of novel compounds, vicinal diaryl-substituted heterocycles are a rich source of leads for the development of new drugs. Their adaptability means that they can be used to produce structures with a broad range of attractive characteristics, and a large number of vicinal diaryl-substituted heterocyclic compounds have already been synthesized and investigated by medicinal chemists as promising lead molecules.</p> <ul> <li>Collects together details of the key vicinal diaryl-substituted heterocyclic compounds in one place for the first time</li> <li>Highlights biological activities and SAR of derivatives</li> <li>Structured practically for ease of navigation between different derivatives</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 19,773円

Science of Synthesis: Houben-Weyl Methods of Molecular Transformations Vol. 9 Fully Unsaturated Small-Ring Heterocycles and Monocyclic Five-Membered Hetarenes with One Heteroatom【電子書籍】

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<p>Science of Synthesis: Houben-Weyl Methods of Molecular Transformations is the entirely new edition of the acclaimed reference series, Houben-Weyl, the standard synthetic chemistry resource since 1909. This new edition is published in English and will comprise of 48 volumes published between the years 2000 and 2008.</p> <p>Science of Synthesis is a quality reference work developed by a highly esteemed editorial board to provide a comprehensive and critical selection of reliable organic and organometallic synthetic methods. Science of Synthesis is designed to be the first point of reference when searching for a synthesis strategy.</p> <p>This volume covers the synthesis of three- and four-membered heterocycles with maximum unsaturation and of five-membered hetarenes with one oxygen, sulfur, selenium, tellurium, nitrogen, or phosphorus atom. Maximum unsaturation means that the ring does not contain either an sp3-hybridized carbon atom or a heteroatom incapable of pi-conjugation. Some compounds which are derivatives of such ring systems but no longer feature maximum unsaturation are also included.</p> <p>For full information on the Science of Synthesis series, visit the <a href="www.science-of-synthesis.com/">Science of Synthesis Homepage</a>.</p> <p>Series Editors: D. Bellus, S. V. Ley, R. Noyori, M. Regitz, E. Schaumann, I. Shinkai, E. J. Thomas, B. M. Trost, P. J. Reider</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 299,646円

Synthesis of Heterocycles via Metal-Catalyzed Reactions that Generate One or More Carbon-Heteroatom Bonds【電子書籍】

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<p>Synthesis of Saturated Heterocycles via Metal-Catalyzed Alkene Carboamination or Carboalkoxylation Reactions, by John P. Wolfe Synthesis of Saturated Heterocycles via Metal-Catalyzed Alkene Diamination, Aminoalkoxylation, or Dialkoxylation Reactions, by Sherry R. Chemler Synthesis of Heterocycles via Metal-Catalyzed Wacker-Type Oxidative Cyclization Reactions of Alkoxy- or Amino-Alkenes, by Wanbin Zhang Synthesis of Saturated Heterocycles via Metal-Catalyzed Hydroamination or Hydroalkoxylation Reactions, by Lisa D. Julian Synthesis of Saturated Heterocycles via Metal-Catalyzed Allylic Alkylation Reactions, by Aaron Aponick Synthesis of Heterocycles via Metal-Catalyzed Cascade/Domino Reactions that Generate a C?N or C?O Bond, by Mark Lautens Synthesis of Saturated Heterocycles via Metal-Catalyzed Formal Cycloaddition Reactions that Generate a C?N or C?O Bond, by Jerome Waser</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 18,231円

N-Sulfonated-N-Heterocycles Synthesis, Chemistry, and Biological Applications【電子書籍】[ Rasha A. Azzam ]

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<p>N-Sulfonated-N-Heterocycles covers the synthesis, chemistry and biological applications of these compounds, focusing on pioneering synthetic approaches, mechanistic insights and their limitations, as well as recent advances in this field. The synthesis of some of N-sulfonated N-heterocycles and their transformation to other useful cyclic and acyclic compounds are discussed, as well as their uses as useful intermediates in the preparation of polymeric and medicinal materials. This book includes detailed methods and protocols, and the focus on applications makes this resource an essential guide for all researchers in the area of organic, medicinal and polymeric synthetic study.</p> <ul> <li>Reviews the use of N-sulfonated N-heterocycles as important precursors for the synthesis of biologically active compounds</li> <li>Includes information on synthetically useful transformations of N-sulfonated N-heterocycles</li> <li></li> <li>Covers a wide synthetic methods used for an important branch of heterocycles and their biological evaluation in detail</li> <li>Features over 500 schemes to illustrate different synthetic pathways and reactions of N-sulfonated N-heterocycles</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 22,244円

Heterocycles Synthesis, Catalysis, Sustainability, and Characterization【電子書籍】[ Teresa M.V.D. Pinho e Melo ]

楽天Kobo電子書籍ストア
<p><strong>Heterocycles</strong></p> <p><strong>A must-read handbook on heterocycle chemistry with a focus on sustainability</strong></p> <p>Heterocycles feature prominently in our daily lifeーthey are essential for pharmaceuticals, agrochemicals, and fine chemicals. More, numerous natural, bioactive products contain heterocyclic compounds. As a result, heterocyclic chemistry continues to be one of the most important areas of study in organic chemistry.</p> <p><em>Heterocycles</em> provides an important reference on a wide range of topics relating to heterocyclic chemistry, with a heavy emphasis on sustainable methods and greener syntheses. The book describes state-of-the-art synthetic methods, such as photochemical reactions, dearomatization reactions, organocatalysis, transition metal catalysis, and biocatalysis. It also covers:</p> <ul> <li>Sustainable methods, like flow chemistry, mechanochemistry, and multicomponent synthesis</li> <li>Strategies for the synthesis of heterocyclic macrocycles and medium-sized rings</li> <li>Characterization of heterocyclic compounds</li> </ul> <p><em>Heterocycles</em> is a useful reference for organic chemists, natural products chemists, catalytic chemists, and medicinal chemists in academia and industry.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 22,642円

Copper(I) Chemistry of Phosphines, Functionalized Phosphines and Phosphorus Heterocycles【電子書籍】

楽天Kobo電子書籍ストア
<p><em>Copper(I) Complexes of Phosphines, Functionalized Phosphines and Phosphorus Heterocycles</em> is a comprehensive guide to one of the most widely used and extensively studied metals: copper. The numerous practical applications of copper compounds are discussed, including homogeneous and heterogeneous catalysis and their use as fungicides, pesticides, pigments for paints, resins and glasses, and in high-temperature superconductors. The remarkable structural flexibility of simple copper(I) complexes, such as cuprous halides is covered, including numerous structural motifs that, when combined with different ligand systems, exhibit linear, trigonal planar or tetrahedral geometries.</p> <p>This work is an essential reference for inorganic and coordination chemists, as well as researchers working on catalysis, anticancer reagents, luminescence, fluorescence and photophysical aspects.</p> <ul> <li>Discusses the properties of copper and similarities to noble metals, such as their corrosion resistance, high thermal and electrical conductivity and rich coordination chemistry</li> <li>Includes the copper(I) coordination chemistry of tertiary phosphines, bisphosphines and phosphines containing other donor atoms and their potential application in catalysis, biosystems and photochemical areas</li> <li>Features a discussion of the rich photochemistry exhibited by some mixed-ligand copper(I) complexes (phosphines with heteroaromatic ligands) which can exhibit coprophilic interactions, photoluminescence and thermochromic properties</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 22,244円

Heterocycles from Double-Functionalized Arenes: Transition Metal Catalyzed Coupling Reactions HETEROCYCLES FROM DOUBLE-FUNCT (Catalysis) [ Xiao-Feng Wu ]

楽天ブックス
HETEROCYCLES FROM DOUBLEーFUNCT Catalysis XiaoーFeng Wu Matthias Beller ROYAL SOCIETY OF CHEMISTRY2015 Hardcover English ISBN:9781782621362 洋書 Computers & Science(コンピューター&科学) Science 64,046円

Nanocatalysis Synthesis of Bioactive Heterocycles【電子書籍】

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<p>The field of nanocatalysis is undergoing rapid development. Nanocatalysis can help in designing catalysts with excellent activity, greater selectivity, and high stability. Their properties can easily be tuned by tailoring the size, shape, and morphology of the particular nanomaterial. Exhibiting both homogeneous and heterogeneous catalytic properties, nanocatalysts allow for rapid and selective chemical transformations, with the benefits of excellent product yield and ease of catalyst separation and recovery.</p> <p><em><strong>Nanocatalysis: Synthesis of Bioactive Heterocycles</strong></em> reviews the catalytic performance and the synthesis and characterization of nanocatalysts, examining the current state of the art and pointing the way towards new avenues of research specially synthesis of bioactive heterocycles.</p> <p>Top researchers summarize synthetic methodologies for the synthesis of bioactive heterocycles using a nanocatalytic framework. The catalytic performance and the synthesis and characterization of nanocatalysts are reviewed. State of the art methods and new and emerging applications of nanocatalysts in the synthesis of biologically active heterocycles are detailed. Additional features include:</p> <ul> <li>Focuses on designing and synthesizing nanocatalysts specifically for the synthesis of different bioactive heterocycles.</li> <li>Demonstrates how nanocatalysis can produce catalysts with excellent activity, greater selectivity, and high stability.</li> <li>Explores tuning catalysts properties by tailoring the size, shape, and morphology of a nanomaterial.</li> <li>Offers the reader insights into the field of nanoscience via nanocatalysis.</li> </ul> <p><em><strong>Nanocatalysis: Synthesis of Bioactive Heterocycles</strong></em> is a must read for researchers in organic chemistry, medicinal chemistry and biochemistry.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 8,945円

Heterocycles via Cross Dehydrogenative Coupling Synthesis and Functionalization【電子書籍】

楽天Kobo電子書籍ストア
<p>This book discusses the developments in the synthesis and functionalization of different heterocycles based on the formation of carbon-carbon (C-C) and carbon-heteroatom (C-X) bonds using cross-dehydrogenative coupling (CDC). Consisting of 13 chapters, the book systematically describes the advances in the synthesis and functionalization of nitrogen, oxygen, and sulfur-containing heterocycles. It also discusses the various mechanistic pathways to help readers gain an in-depth understanding of the CDC reactions of heterocycles. Lastly, in order to promote green chemistry, it addresses a range of metal-free CDC reactions of heterocycles ? an area that has attracted significant attention in both academic and industrial research.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 15,800円

Palladium Assisted Synthesis of Heterocycles【電子書籍】[ Navjeet Kaur ]

楽天Kobo電子書籍ストア
<p>This book is a compilation of the recent applications of palladium catalysts in organic synthesis. The book demonstrates that it is a highly dynamic research field. This methodology has emerged as a powerful tool for the efficient and chemoselective synthesis of heterocyclic molecules. In the past few years, several strategies have been pointed out to pursue more efficient, sustainable, and environment friendly chemical processes. Among those strategies, catalysis and the design of new processes that avoid the use of toxic reagents have been the focus of intense research.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 8,252円

Halogenated Heterocycles Synthesis, Application and Environment【電子書籍】

楽天Kobo電子書籍ストア
<p>G. Sandford: Perfluoroheteroaromatic Chemistry: Multifunctional Systems from Perfluorinated Heterocycles by Nucleophilic Aromatic Substitution Processes.- A. A. Gakh: Monofluorinated Heterocycles.- R. Dembinski ? Y. Li ? D. Gundapuneni ? A. Decker: Synthesis of beta-Halofurans.- Y. Shermolovich ? S. Pazenok: Synthesis of halogenated 5- and 6-membered sulfur- and Sulfur, Nitrogen Containing Heterocycles.- S. Minakata ? Y. Takeda ? J. Hayakawa: Heterocyclic Reagents Containing Nitrogen-Halogen Bond: Recent Applications.- Michael Schn?rch: Recent Progress on the Halogen Dance Reaction on Heterocycles.- T. Kosjek ? E. Heath: Halogenated Heterocycles as Pharmaceuticals.- E. Heath ? T. Kosjek: Sources, Occurrence and Fate of Halogenated Heterocyclic Pharmaceuticals in the Environment.- J. Iskra: Green Methods in Halogenation of Heterocycles.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 13,369円

Phosphorus Heterocycles II【電子書籍】

楽天Kobo電子書籍ストア
<p>Contents: S. Sasaki: Heterophenes Carrying Phosphorus Functional Groups as Key Structures.- D.D. Enchev: Synthesis and Biological Activity of 2,5-Dihydro-1,2-Oxaphosphole-2-Oxide Derivatives.- D. Gudat: Recent Developments in the Chemistry of N -Heterocyclic Phosphines.- J. Drabowicz ? D. Krasowska ? A. ?opusi?ski ?T.S.A. Heugebaert ? C.V. Stevens: Selected Five-Membered Phosphorus Heterocycles Containing a Stereogenic Phosphorus.- G. Keglevich: 1-(2,4,6-Trialkylphenyl)-1 H -Phospholes with a Flattened P-Pyramid: Synthesis and Reactivity.- N. Gupta: Recent Advances in the Chemistry of Diazaphospholes</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 24,309円

Synthesis of Saturated Oxygenated Heterocycles II 7- to 16-Membered Rings【電子書籍】

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<p>The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 24,309円

Free-Radical Synthesis and Functionalization of Heterocycles【電子書籍】

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<p>This volume describes the recent developments in the free-radical mediated synthesis and elaboration of heterocycles. The first chapter, dealing with radical cascade processes illustrates the power and the beauty of radical chemistry with some striking examples of total synthesis of complex natural heterocycles. As organic chemists strive towards sustainability, radical chemistry has recently seen major advances and efforts in this direction, including C-H activation of arenes and unactivated alkyl groups. Photochemical activation, for a long time the preferred mode of activation in radical chemistry has also seen an unexpected revival with the advent of visible light metal- and organocatalyzed photoredox processes. A survey of these emerging areas is provided along with the concepts at the origin of these developments.</p> <p>The venerable Minisci reaction allows for direct access to functionalized heterocycles. This process has lately seen an interesting renaissance and is discussed in this volume. Addition of heteroatom-centered radicals onto unsaturated systems constitutes another powerful method to construct heterocycles. Examples of such a strategy are proposed along with the formation of various heterocycles relying on homolytic substitution at sulfur, phosphorus and selenium. Additionally free-radical functionalization of reactive functional groups including isonitriles, isothiocyanates and related unsaturated systems which offer a straightforward route towards useful aromatic and non-aromatic heterocycles are discussed. Finally, as metals are able to trigger single electron transfer both in reductive and oxidative modes this provides another possibility for the synthesis of heterocycles. Significant research efforts have focused on the use of samarium, copper and other metals to access a broad variety of heterocycles in a single pot process, starting from readily available raw material. Examples and mechanistic insights are discussed by experts in thisarea.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 34,033円

Biosynthesis of Heterocycles From Isolation to Gene Cluster【電子書籍】[ Patrizia Diana ]

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<p>This book describes biosynthetic methods to synthesize heterocyclic compounds, offering a guide for the development of new drugs based on natural products. The authors explain the role of natural products in chemistry and their formation along with important analytical methods and techniques for working with heterocycles.</p> <p>? Covers methods and techniques: isotopic labelling, enzymes and mutants, and pathway identification<br /> ? Provides a thorough resource of information specifically on heterocyclic natural products and their practical biosynthetic relevance<br /> ? Explains the role of natural products in chemistry and their formation<br /> ? Discusses gene cluster identification and the use of biogenetic engineering in pharmaceutical application</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 25,493円

Fluorine in Heterocyclic Chemistry Volume 2 6-Membered Heterocycles【電子書籍】

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<p>This two-volume work combines comprehensive information on the chemistry of the fluorinated heterocycles. The material has been divided such that the first volume is dedicated to 5-membered fluorinated heterocycles and macrocycles, while the second volume combines data connected with the chemistry of fluorine containing 6-membered heterocycles. Both volumes will be of interest to synthetic organic chemists in general, and particularly for those colleagues working in the fields of heterocyclic-compound chemistry, materials chemistry, medicinal chemistry, and fluorine chemistry. All information is presented and classified clearly to be effective source for broad auditory of chemists. It will be interesting for scientists working in the field of inorganic and coordination chemistry. Fluorinated heterocycles are becoming increasingly important in many areas including the pharmaceutical industry, materials science and agriculture. The presence of fluorine can result in substantial functional changes in the biological as well as physicochemical properties of organic compounds. Incorporation of fluorine into drug molecules can greatly affect their physicochemical properties, such as bond strength, lipophilicity, bioavailability, conformation, electrostatic potential, dipole moment, pKa etc. as well as pharmacokinetic properties, such as tissue distribution, rate of metabolism and pharmacological properties, such as pharmacodynamics and toxicology.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 18,231円

Palladium and Nickel Catalyzed Transformations Forming Functionalized Heterocycles【電子書籍】[ Hyung Yoon ]

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<p>This book presents Pd- and Ni-catalyzed transformations generating functionalized heterocycles. Transition metal catalysis is at the forefront of synthetic organic chemistry since it offers new and powerful methods to forge carbon?carbon bonds in high atom- and step-economy.</p> <p>In Chapter 1, the author describes a Pd- and Ni-catalyzed cycloisomerization of aryl iodides to alkyl iodides, known as carboiodination. In the context of the Pd-catalyzed variant, the chapter explores the production of enantioenriched carboxamides through diastereoselective Pd-catalyzed carboiodination. It then discusses Ni-catalyzed reactions to generate oxindoles and an enantioselective variant employing a dual ligand system.</p> <p>Chapter 2 introduces readers to a Pd-catalyzed diastereoselective anion-capture cascade. It also examines diastereoselective Pd-catalyzed aryl cyanation to synthesize alkyl nitriles, a method that generates high yields of borylated chromans as a single diastereomer, andhighlights its synthetic utility.</p> <p>Lastly, Chapter 3 presents a Pd-catalyzed domino process harnessing carbopalladation, C?H activation and π-system insertion (benzynes and alkynes) to generate spirocycles. It also describes the mechanistic studies performed on these reactions.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 18,231円

洋書 Paperback, The Chemistry of Heterocycles: Structures, Reactions, Synthesis, and Applications

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Development of New Radical Cascades and Multi-Component Reactions Application to the Synthesis of Nitrogen-Containing Heterocycles【電子書籍】[ Marie-Helene Larraufie ]

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<p>In this dissertation, Marie-H?l?ne Larraufie develops original radical and pallado-catalyzed methodologies to enable the synthesis of several classes of bioactive nitrogen-containing heterocycles. New radical cascades employing the N-acylcyanamide moiety offer straightforward routes to quinazolinones and guanidines, as well as new insights into the mechanism of homolytic aromatic substitutions. In parallel, Larraufie expands the scope of visible light photoredox catalysis to the ring opening of epoxides and aziridines, thus providing new sustainable alternatives for the generation of radicals. Furthermore, in a collaborative effort with the Catellani group, the author investigates dual palladium/norbornene catalysis. First, she develops a C-amination coupling variant of the Catellani reaction with unprotected amines which provides an expeditious route to phenanthridines. Then, she examines the influence of the chelating effect on Pd(IV) intermediates reactivity with the help of experimental studies and DFT calculations. The work in this thesis has resulted in numerous publications in high impact journals.The clarity and depth of the experimental section will be useful for students and researchers working in this field.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 12,154円

Photochemistry of Heterocycles【電子書籍】[ Maurizio D’Auria ]

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<p><em>Photochemistry of Heterocycles</em> is a comprehensive review of the topic, including photooxidation, photoreduction and photoaddition reactions as well as industrial aspects of heterocyclic photochemistry. Many materials used for the manufacturing of OLEDs and other electrooptical switches contain heterocycles, and the use of small molecules or polymers containing heterocyclic substances are being studied as new photovoltaic materials. This reference is ideal for synthetic organic chemists, specifically researchers working in organic photochemistry, as well as medicinal chemists and material scientists.</p> <p>Heterocyclic compounds are widely used in the modern world, and most of the drugs currently in use have heterocyclic nuclei among their constituents. These compounds are subject to a photochemical degradation processes which must be known and prevented.</p> <ul> <li>Presents an authoritative and comprehensive review of the photochemistry of heterocycles</li> <li>Covers the full spectrum of photochemical reactivity, including photoreduction and photoaddition reactions of heterocyclic compounds</li> <li>Includes industrial aspects of heterocyclic photochemistry and materials used to manufacture OLEDs and other electrooptical switches</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 22,244円

Science of Synthesis: Houben-Weyl Methods of Molecular Transformations Vol. 17 Six-Membered Hetarenes with Two Unlike or More than Two Heteroatoms and Fully Unsaturated Larger-Ring Heterocycles【電子書籍】

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<p>Science of Synthesis: Houben-Weyl Methods of Molecular Transformations is the entirely new edition of the acclaimed reference series, Houben-Weyl, the standard synthetic chemistry resource since 1909. This new edition is published in English and will comprise 48 volumes published between the years 2000 and 2008.</p> <p>Science of Synthesis is a quality reference work developed by a highly esteemed editorial board to provide a comprehensive and critical selection of reliable organic and organometallic synthetic methods. This unique resource is designed to be the first point of reference when searching for a synthesis strategy.</p> <ul> <li>Contains the expertise of presently 400 leading chemists worldwide</li> <li>Critically evaluates the preparative applicability and significance of the synthetic methods</li> <li>Discusses relevant background information and provides detailed experimental procedures</li> </ul> <p>For full information on the Science of Synthesis series, visit the <a href="www.science-of-synthesis.com/">Science of Synthesis Homepage</a>.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 227,004円

Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, 2 Volumes【電子書籍】

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<p><strong>Transition-Metal-Catalyzed C-H Functionalization of Heterocycles</strong></p> <p><strong>A comprehensive guide to recent advances in this field</strong></p> <p>Constituting the majority of all known compounds, heterocycles are structures that incorporate one or more heteroatoms within their core, thus exhibiting properties that are quite different from their all-carbon analogs. They are fundamental to all fields of chemistry and, therefore, their synthesis and modification has attracted a great deal of attention in the recent years. In this vein, transition-metal-catalyzed C-H bond functionalization forms a crucial tool for generating and analyzing heterocyclic compounds.</p> <p><em>Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, Two-Volume Set</em>, showcases diverse C-H functionalization methodologies and their incorporation into the latest research. The chapters serve as an essential tool depicting detailed site-selective functionalization of heterocyclic cores, along with a comprehensive discussion on their mechanistic approaches.</p> <p>Readers of <em>Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, Two-Volume-Set</em> will also find:</p> <ul> <li>A detailed introduction to C-H activation along with the mechanistic aspects of transition-metal-catalyzed C-H bond activation reactions</li> <li>Easy-to-use structures with each chapter dedicated to a type of heterocycle and its specific functionalization methodologies</li> <li>A leading team of international authors in C-H bond functionalization</li> </ul> <p><em>Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, Two-Volume-Set</em> is a valuable guide for students and researchers in organic synthesis and process development, in both academic and industrial contexts.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 46,540円

Metal and Nonmetal Assisted Synthesis of Six-Membered Heterocycles【電子書籍】[ Navjeet Kaur, BSc; MSc ]

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<p><em>Metal and Nonmetal Assisted Synthesis of Six-Membered Heterocycles</em> provides a useful guide to key approaches being explored in this area. The volume highlights synthetic approaches and catalytic options that facilitate the construction of multiple substituted molecules under mild conditions from easily available starting substrates. Drawing on the experience of its expert author, the book is a useful guide on the key approaches being explored in this area. Following a user-friendly structure based on specific six-membered heterocycle ring groups, this volume highlights synthetic approaches and catalytic options that facilitate the construction of multiple substituted molecules under mild conditions from easily available starting substrates.</p> <ul> <li>Highlights new methodologies for the synthesis of different six-membered heterocycles</li> <li>Provides an up-to-date overview of this fast-moving field with an easy-to-use structure</li> <li>Includes novel approaches used in the study and application of catalysts in synthetic organic reactions</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 20,761円

Synthesis of Heterocycles via Multicomponent Reactions II【電子書籍】

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<p>G?raldine Masson, Luc Neuville ? Carine Bughin ? Aude Fayol ? Jieping Zhu Multicomponent Syntheses of Macrocycles Thomas J.J. M?ller Palladium-Copper Catalyzed Alkyne Activation as an Entry to Multicomponent Syntheses of Heterocycles Rachel Scheffelaar ? Eelco Ruijter ? Romano V.A. Orru Multicomponent Reaction Design Strategies: Towards Scaffold and Stereochemical Diversity Nicola Kielland ? Rodolfo Lavilla Recent Developments in Reissert-Type Multicomponent Reactions Jitender B. Bariwal ? Jalpa C. Trivedi ? Erik V. Van der Eycken Microwave Irradiation and Multicomponent Reactions Irini Akritopoulou-Zanze ? Stevan W. Djuric Applications of MCR-Derived Heterocycles in Drug Discovery</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 48,619円

Heterocycles as Chiral Auxiliaries in Asymmetric Synthesis【電子書籍】

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<p>The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 24,309円

More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles, 2 Volume Set【電子書籍】[ Ana Maria Faisca Phillips ]

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<p><strong>More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles</strong></p> <p><strong>An authoritative collection of resources discussing the latest trends in the synthesis of nonaromatic nitrogen heterocycles</strong></p> <p>Widely distributed in nature, nitrogen heterocycles are extremely common in synthetic substances found in pharmaceuticals, agrochemicals, and materials. The literature is evolving rapidly and explores newly emerging structures and medicines. <em>More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles</em> offers R&D professionals the opportunity to easily access a collection of the latest relevant research in the area.</p> <p>In the second two-volume set of this practical reference distinguished researcher Dr. Ana Maria M. M. Faisca Phillips delivers a collection of resources focusing on the newest and most widely applicable trends emerging in synthetic strategies for nonaromatic nitrogen heterocycles. With coverage of topics including organocatalysis, cascade reactions, flow chemistry in synthesis, cycloaddition reactions, metathesis, cross-coupling reactions, and electrochemistry, the book provides quick access to critical new avenues of synthesis.</p> <p><em>More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2</em> also offers readers:</p> <ul> <li>A thorough introduction to recent advances in the design and synthesis of cyclic peptidomimetics</li> <li>Comprehensive explorations of fused heterocycles and transition metal promoted synthesis of isoindoline derivatives</li> <li>Practical discussions of 1,4-diazepane ring-based systems and recent advances in the synthesis of azepane-based compounds</li> <li>In-depth examinations of strained aziridinium ions, asymmetric organocatalysis in alternative media, and the electrochemical synthesis of non-aromatic N-heterocycles</li> </ul> <p>Perfect for academic and industrial researchers in organic chemistry and synthesis, organometallic chemistry, pharmaceutical chemistry catalysis, and sustainable chemistry, <em>More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2</em> is an indispensable reference for anyone seeking an authoritative source of information on new and emerging trends in synthesis.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 39,236円

Multicomponent Reactions Synthesis of Bioactive Heterocycles【電子書籍】

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<p>This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 7,901円

Synthesis of Heterocycles via Multicomponent Reactions I【電子書籍】

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<p>Contents: L. Banfi ? A. Basso ? R. Riva: Synthesis of Heterocycles Through Classical Ugi and Passerini Reactions Followed by Secondary Transformations Involving One or Two Additional Functional Groups.- V.A. Chebanov ? K. A. Gura ? S.M. Desenko: Aminoazoles as Key Reagents in Multicomponent Heterocyclizations.- Y. Huang ? K. Khoury ? A. D?mling: Piperazine Scaffolds by Multicomponent 3 Reactions: The Piperazine Space 4 in MCR Chemistry 5 Deep MCR Piperazine Space.- N. Elders ? E. Ruijter ? V.G. Nenajdenko ? R.V.A. Orru: α-Acidic Isocyanides in Multicomponent Chemistry.- A. Cukalovic ? J.-C.M.R. Monbaliu ? C.V. Stevens: Microreactor Technology as an Efficient Tool for Multicomponent Reactions.- L.A. Wessjohann ? C.R.B. Rhoden ? D.G. Rivera ? O. Eichler Vercillo: Cyclic Peptidomimetics and Pseudopeptides from Multicomponent Reactions.- M. del Mar Sanchez Duque ? C. Allais ? N. Isambert ? T. Constantieux ? J. Rodriguez: ?-Diketo Building Blocks for MCRs-Based Syntheses of Heterocycles</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 36,464円