Oncogenes

Oncogenes 電子書籍
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商品	説明	価格
Genes, Oncogenes, and Hormones Advances in Cellular and Molecular Biology of Breast Cancer【電子書籍】楽天Kobo電子書籍ストア	＜p＞Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes that aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, and easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion: first, by dividing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc.; and second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current di agnosis, staging, markers, all forms of treatment modalities, basic biology, and more.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	36,464円
Oncogenes as Transcriptional Regulators Cell Cycle Regulators and Chromosomal Translocation【電子書籍】楽天Kobo電子書籍ストア	＜p＞The intensive study of molecular events leading to cellular transformation in tissue culture or in intact organisms culminated in the identification of 100 or more genes that can be defined as oncogenes or tumor suppressor genes. Functionally, these genes can be divided into several classes, each involved in a different step in transmission of signals from the exterior of the cell to the nucleus. The first oncogenes to be biochemically character ized included membrane receptors for growth factors, growth factors themselves, protein kinases or small GTP binding proteins involved in signal transduction. Later, the development of techniques to study pro teins-DNA interaction in eucaryotes and the isolation and characterization of many promoter and enhancer sequences revealed that a number of the classical retroviral oncogenes were indeed transcription factors. In paral lel, the rapid progress in the identification and cloning of chromosomal translocations in human and animal malignancies and the increased reper toire of known transcription factors families revealed that many other transcription factors can playa critical role in cancer. A more recent devel opment concerns tumor suppressor genes. The realization that human tumors are frequently associated with a loss of function of one or several genes is also one of the landmarks of cancer research in the last 15 years. Again, as we will see below, some of these genes encode transcription factors. It is becoming increasingly difficult to cover in a single monograph all oncogenes and tumor suppressor genes.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	6,076円
洋書 Paperback, Oncogenes and Growth Control Glomarket	* We ship internationally, so do not use a package forwarding service. We cannot ship to a package forwarding company address because of the Japanese customs regulation. If it is shipped and customs office does not let the package go, we do not make a refund. 【注意事項】 * 特に注意してください。 * ・個人ではない法人・団体名義での購入はできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。・お名前にカタカナが入っている場合法人である可能性が高いため当店システムから自動保留します。カタカナで記載が必要な場合はカタカナ変わりローマ字で記載してください。・お名前またはご住所が法人・団体名義（XX株式会社等）、商店名などを含めている場合、または電話番号が個人のものではない場合、税関から法人名義でみなされますのでご注意ください。・転送サービス会社への発送もできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 * ・注文後品切れや価格変動でキャンセルされる場合がございますので予めご了承願います。・当店でご購入された商品は、原則として、「個人輸入」としての取り扱いになり、すべてニュージャージからお客様のもとへ直送されます。・ご注文後、30営業日以内(通常2~3週間)に配送手続きをいたします。配送作業完了後、2週間程度でのお届けとなります。・まれに商品入荷状況や国際情勢、運送、通関事情により、お届けが2ヶ月までかかる場合がありますのでお急ぎの場合は注文をお控えください。・個人輸入される商品は、すべてご注文者自身の「個人使用・個人消費」が前提となりますので、ご注文された商品を第三者へ譲渡・転売することは法律で禁止されております。・関税・消費税が課税される場合があります。詳細はこちらをご確認下さい。PC販売説明文	20,130円
Oncogenes Meet Metabolism From Deregulated Genes to a Broader Understanding of Tumour Physiology【電子書籍】楽天Kobo電子書籍ストア	＜p＞In 1920s, Otto Warburg described the phenomenon of ‘aerobic glycolysis’, the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions. Warburg’s hypothesis of an altered metabolism in cancer cells found no immediate acceptance, though it was latter confirmed for most human tumours. With the advent of molecular biology the focus in tumour research has shifted towards the search for oncogenes. However, the interest in cancer molecular profiling eventually led to a renaissance of the Warburg effect trying to combine genetic alterations with effects on metabolism with the help of modern analytic technologies to rapidly analyze broad varieties of metabolites in various tissues and bodyfluids (metabonomics).＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	18,231円
RNA Tumor Viruses, Oncogenes, Human Cancer and AIDS: On the Frontiers of Understanding Proceedings of the International Conference on RNA Tumor Viruses in Human Cancer, Denver, Colorado, June 10?14, 1984【電子書籍】楽天Kobo電子書籍ストア	＜p＞We stand today on the threshold of a new understanding of cancer. Primarily through the powerful tools of molecular biology, unified hypotheses explaining the origins of the disease are emerging and rapidly being validated. This volume, which presents the latest findings from laboratories throughout the world on the role of RNA tumor viruses in cancer, is a celebration of these achievements and a prediction of further progress leading ultimately to the control of the disease. It is important in this context to recall the natural history or life cycle of RNA cancer virology. From the earliest days of the science, when viruses were first recognized as distinct biologic agents of etiologic significance, their role in cancer was proposed and hotly debated. The critical early discoveries, even those made as recently as 25 years ago, were met with rejection; not skepticism or cautious restraint, but outright rejection. During the 60's, there was a gradual acceptance of the association between viruses and cancer, the result of landmark studies in experimental systems, and this led to a frenzy of activity in the field. There followed another period of doubt and uncertainty, due to the difficulty in attempting to apply directly, and in retrospect inappropriately, the tenets of infectious disease to human cancers, only to have the field resurrected, revitalized and redirected by the explosion of progress in molecular biology and genetics.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	24,309円
Oncogenes An Introduction to the Concept of Cancer Genes【電子書籍】[ Kathy B. Burck ] 楽天Kobo電子書籍ストア	＜p＞"Cancer viruses" have played a paradoxical role in the history of cancer research. Discovered in 1911 by Peyton Rous (1) at the Rockefeller Institute, they were largely ignored for several decades. Witness his eventual recognition for a Nobel Prize, but not until 1966-setting an all time record for latency, and testimony to one more advantage of longevity. In the 1950s, another Rockefeller Nobelist, Wendell Stanley, spearheaded a campaign to focus attention on viruses as etiological agents in cancer, his plat form having been the chemical characterization of the tobacco mosaic virus as a pure protein-correction, ribonucleoprotein-in 1935 (2). This doctrine was a centerpiece of the U.S. National Cancer Crusade of 1971: if human cancers were caused by viruses, the central task was to isolate them and prepare vaccines for immunization. At that point, many observers felt that perhaps too much attention was being devoted to cancer viruses. It was problematic whether viruses played an etiological role in more than a handful of human cancers.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	12,154円
Introduction to Oncogenes and Molecular Cancer Medicine【電子書籍】[ Dennis W. Ross ] 楽天Kobo電子書籍ストア	＜p＞Scientists now understand that cancer is a genetic disease and cutting -edge molecular therapies are making their way from the laboratory into clinical practice. Introduction to Oncogenes and Molecular Cancer Medicine provides the physician with a solid understanding of molecular biology and its applications for the diagnosis and treatment of cancer. The book reviews the basic molecular principles and the basic principles of cancer medicine, including controls of cell growth and senescence, carcinogenesis, tumorogenesis, and epidemiology. The second part of the book gives clinical examples to demonstrate the basic science principles, including chapters on leukemia, colon cancer, and breast cancer. A chapter on molecular diagnostics and screening plus a chapter on new molecular anti-cancer therapies give the reader a look at current cutting-edge therapies as well as as the future of molecular cancer medicine. A useful glossary defines new terminology at-a-glance. Introduction to Oncogenes and Molecular Cancer Medicine is for all physicians seeking a better understanding of the modern molecular principles of cancer medicine. Written in a user-friendly, conversational format, this text will be welcomed by all physicians eager to sharpen their own understanding of molecular cancer medicine as well as to help them provide patients with balanced information on the advances and limitations of current treatment options.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	6,076円
Carcinogen-Driven Mouse Models of Oncogenesis【電子書籍】[ Lorenzo Galluzzi ] 楽天Kobo電子書籍ストア	＜p＞＜em＞Carcinogen-Driven Mouse Models of Oncogenesis, Volume 163＜/em＞ contains a series of protocols written by world-leading experts in the field. Each manuscript provides a detailed methodological description to drive carcinogen-mediated oncogenesis in mice. Chapters in this new release include Chemical carcinogenesis in mice as a model of human cancer: Pros and cons, MPA/DMBA-driven mammary carcinomas, Dimethylbenz(a)anthracene-Induced Mammary Tumorigenesis in mice, Urethane-induced lung carcinogenesis, Methylcholanthrene-induced fibrosarcomas, BBN-driven bladder carcinomas, Oral squamous cell carcinomas driven by 4NQO, Analyzing skin tumor development in mice by the DMBA/TPA model, and much more.＜/p＞＜p＞Other sections cover DSS/AOM-driven colorectal carcinomas, Diethylnitrosamine-induced liver tumorigenesis in mice, Two-stage 3-methylcholanthrene and butylated hydroxytoluene-induced lung carcinogenesis in mice, Lung carcinomas induced by NNK and LPS, Pristane-induced mammary carcinomas, The 4-NQO mouse model: an update on a well-established in vivo model of oral carcinogenesis, and more.＜/p＞＜ul＞＜li＞Provides protocols provided by renowned experts in the field＜/li＞＜li＞Presents detailed descriptions of protocols, hence allowing appropriate reproduction of the models＜/li＞＜li＞Includes author notes for each protocol, covering useful tips and troubleshooting＜/li＞＜/ul＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	20,354円
HIV/AIDS-Associated Viral Oncogenesis【電子書籍】楽天Kobo電子書籍ストア	＜p＞In this book, leading experts examine the clinical and biological aspects of viruses known to play a role in the oncogenesis of AIDS-associated cancers and non-AIDS-defining malignancies more commonly observed in HIV-infected individuals. Among the malignancies considered are those associated with Kaposi sarcoma-associated herpesvirus (KSHV) or Epstein?Barr virus (EBV), Merkel cell carcinoma due to Merkel cell polyomavirus (MCPyV), human papillomavirus (HPV)-associated anogenital and oropharyngeal cancers, and hepatitis B and C virus (HBV/HCV)-associated liver cancers. It also provides detailed information on the molecular biology of the causative viral agents and guidance on the specific treatment required in this special population. Covering all the important advances in our understanding made since the first edition was published in 2007, including the discovery and characterization of MCPyV, which brought the number of known human oncoviruses to seven, this new edition is a valuable resource for members of the scientific and healthcare community and active researchers in this field.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	12,154円
Adaptive Oncogenesis A New Understanding of How Cancer Evolves inside Us【電子書籍】[ James DeGregori ] 楽天Kobo電子書籍ストア	＜p＞Popular understanding holds that genetic changes create cancer. James DeGregori uses evolutionary principles to propose a new way of thinking about cancer’s occurrence. Cancer is as much a disease of evolution as it is of mutation, one in which mutated cells outcompete healthy cells in the ecosystem of the body’s tissues. His theory ties cancer’s progression, or lack thereof, to evolved strategies to maximize reproductive success.＜/p＞＜p＞Through natural selection, humans evolved genetic programs to maintain bodily health for as long as necessary to increase the odds of passing on our genesーbut not much longer. These mechanisms engender a tissue environment that favors normal stem cells over precancerous ones. Healthy tissues thwart cancer cells’ ability to outcompete their precancerous rivals. But as our tissues age or accumulate damage from exposures such as smoking, normal stem cells find themselves less optimized to their ecosystem. Cancer-causing mutations can now help cells adapt to these altered tissue environments, and thus outcompete normal cells. Just as changes in a species’ habitat favor the evolution of new species, changes in tissue environments favor the growth of cancerous cells.＜/p＞＜p＞DeGregori’s perspective goes far in explaining who gets cancer, when it appears, and why. While we cannot avoid mutations, it may be possible to sustain our tissues’ natural and effective system of defense, even in the face of aging or harmful exposures. For those interested in learning how cancers arise within the human body, the insights in ＜em＞Adaptive Oncogenesis＜/em＞ offer a compelling perspective.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	5,128円
Cell Growth and Oncogenesis【電子書籍】楽天Kobo電子書籍ストア	＜p＞Rapid progress has been made in our understanding of the molecular mechanisms of cell growth and oncogenesis during the past decade. This book comprises recent results on the regulation of cell growth in normal and neoplastic tissues by growth factors including hormones, and by the activation and inactivation of oncogenes and tumor suppressor genes, respectively. Special attention has been given to the presentation of the frequently neglected close correlation between changes in signal transduction and metabolism pathways during oncogenesis.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	24,309円
Epigenetic Alterations in Oncogenesis【電子書籍】楽天Kobo電子書籍ストア	＜p＞The purpose of this book is to provide an up to date review of the nature and consequences of epigenetic changes in cancer. Epigenetics literally means “above” genetics, and consists of heritable gene expression or other phenotypic states not accounted for by DNA base sequence. Epigenetic changes are now known to make a large contribution to various aspects of tumorigenesis. These changes include alterations in global and promoter specific DNA methylation, activating and repressive histone modifications, and changes in higher order chromatin structures. Each of these topics will be covered in this book.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	18,231円
Molecular Mechanisms of Angiogenesis From Ontogenesis to Oncogenesis【電子書籍】楽天Kobo電子書籍ストア	＜p＞Angiogenesis is a multi-stage process that drives the generation of new blood and lymphatic vessels from pre-existing ones. It is highly active during embryogenesis, largely inactive during adulthood but reactivated during wound healing and under a number of pathological conditions including cancer and ocular diseases. In addition to endothelial cells, which line the walls of the vessels, several other cell types (pericytes, macrophages, progenitor cells…) also contribute to angiogenesis. A number of signaling pathways are activated and very finely tune the delicate morphogenetic events that ultimately lead to the formation of stable blood proof neovessels.＜/p＞＜p＞This book reviews recent advances in our understanding of the molecular and cellular mechanisms of angiogenesis, with a focus on how to integrate these observations into the context of developmental, post-natal and pathological neovascularization.＜/p＞＜p＞The book was published under the auspices of the French Angiogenesis Society. Most contributors are prominent members of this Society or international researchers who have actively contributed to the Annual Meetings of the Society.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	13,369円
MicroRNAs: Key Regulators of Oncogenesis【電子書籍】楽天Kobo電子書籍ストア	＜p＞Aberrant expression and function of microRNAs (miRNAs) in cancer have added a new layer of complexity to the understanding of development and progression of the disease state. It has been demonstrated that miRNAs have a crucial function in oncogenesis by regulating cell proliferation and apoptosis as oncogenes or tumor suppressors. The expression signatures of miRNAs provide exciting opportunities in the diagnosis, prognosis and therapy of cancer. Since miRNAs can function as either oncogenes or tumor suppressor genes in oncogenesis, the potential of using these small RNAs as therapeutic targets opens up new opportunities for cancer therapy by either inhibiting or augmenting their activity.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	18,231円
Mechanisms of Oncogenesis An update on Tumorigenesis【電子書籍】楽天Kobo電子書籍ストア	＜p＞This volume is part of a book series that was first published in 10-volumes by Kluwer in 1989 under the series editorship of Professor Hans E. Kaiser, D.Sc., former Professor of Pathology at the School of Medicine, University of Maryland at Baltimore, MD, USA along with other leaders in the field of Cancer. In order to encompass the growing body of knowledge on various aspects of cancer growth and progression since then, the series has now been expanded to 17 volumes.＜/p＞＜p＞This volume is a comprehensive update on the mechanisms of tumorigenesis, and includes the advances in the field, as provided by the use of the most recent molecular techniques (microarray, proteomic, and other omics). While the first portion of the book contains chapters discussing pediatric cancer, the influence of environmental factors and oncogene activity in tumorigenesis, the second portion of the book is structured by organ sites (Esophagus, Breast, Pancreas, Colon, Lung, Prostate, Skin, Brain, Endocrine System, Lymphoid System, Bone, Head and Neck, and Cervix). This format provides the reader with easy access to the needed information.＜/p＞＜p＞This definitive text will offer the medical professionals, whether in research, academia or clinical practice, the latest information endorsed by the world renowned contributors. The broad range of topics will make this a valued reference and provide a wealth of information, making this a "state of the science" on carcinogenesis.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	24,309円