Pharmacogenomics

Pharmacogenomics 電子書籍
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商品	説明	価格
Pharmacogenomics: Foundations, Competencies, and the Pharmacists' Patient Care Process PHARMACOGENOMICS 2/E [ David F. Kisor ] 楽天ブックス	PHARMACOGENOMICS 2/E David F. Kisor AMER PHARMACISTS ASSN2023 Paperback English ISBN：9781582123851 洋書 Computers & Science（コンピューター＆科学） Medical	19,131円
Pharmacogenomics and Precision Medicine, An Issue of the Clinics in Laboratory Medicine【電子書籍】[ Kristen Reynolds, PhD ] 楽天Kobo電子書籍ストア	＜p＞This issue of the Clinics in Laboratory Medicine on “Pharmacogenomics is being edited by Drs. Roland Valdes and Kristen Reynolds and will cover a wide variety of topics, including but not limited to, fundamentals of pharmacology, a review of pharmacogenetics guidelines, pharmacogenetic testing in pain management, pharmacogenetics of pain management, clinical and economic impact of pharmacogenetic genotyping analysis, exosome analysis in lab medicine, and implementation of pharmacogenetics in developing countries.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	8,966円
Pharmacogenomics Challenges and Opportunities in Therapeutic Implementation【電子書籍】楽天Kobo電子書籍ストア	＜p＞＜em＞Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation＜/em＞includes discussions and viewpoints from the academic, regulatory, pharmaceutical, clinical, socio-ethical and economic perspectives. Each chapter presents an overview of the potential or opportunity within the areas discussed and also outlines foreseeable challenges and limitations in moving pharmacogenomics into drug development and direct therapeutic applications. This edited book contains review questions for a more in-depth analysis of the implications of pharmacogenomics and discussion points to generate ideas on best to move the field forward. Clinical pearls and case studies are used to illustrate real-life experiences and both successful and unsuccessful applications. Tables, figures, and annotations are included throughout the book to facilitate understanding and further reference.＜/p＞＜ul＞＜li＞Multi-contributed book and chapters are written by contributors who are experts in their field＜/li＞＜li＞Provides perspectives from those involved in all aspects of pharmacogenomicsーincluding academic, regulatory, economic, industry and medicalーto illustrate how all of the pieces fit together and where the challenges may be＜/li＞＜li＞Includes case studies of both successful and unsuccessful applications so readers can consider the potential and challenges in moving the science into drug development and direct therapeutic applications＜/li＞＜li＞Chapters contain discussion questions and clinical pearls and enable readers to reflect on how to move pharmacogenomics forward and apply these observations and useful tips to their own work and research＜/li＞＜/ul＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	9,882円
Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response【電子書籍】楽天Kobo電子書籍ストア	＜p＞Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response provides the most comprehensive body of knowledge available on the role of genetic and genomic variation in the individualization of drug therapies in cancer patients. As a consequence of the intrinsic chromosomal and genetic instability of the tumor genome, it is generally believed that tailoring of chemotherapy in cancer - tients might be achieved by molecular analysis of patient tumor DNA. In addition, to reduce the toxicity risk of patients, the tumor DNA information should be in- grated with the available data on polymorphic drug-metabolizing enzyme and tra- porter genes mediating the exposure of patients to active drugs and/or their active metabolites. The chapters of this book clearly show how DNA information from both the host (germline) and the tumor should be taken into account for rational selection of drug therapies in cancer patients, an aspect that received little attention, despite its importance. The availability of new molecular approaches to the selection of drug therapy is an emerging need, because the traditional approach based on the evaluation of patient and tumor characteristics is clearly far from optimal. Many treated patients do not experience signi?cant bene?ts from the treatment, while they often experience moderate to severe toxicities. In addition, the development and clinical use of novel molecularly targeted agents (alone or in combination with classical cytotoxic therapy) requires the und- standing of the molecular features of the tumors and the identi?cation of tumor markers of response.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	24,309円
Pharmacogenomics and the Future of Personalized Treatments【電子書籍】[ Edenilson Brandl ] 楽天Kobo電子書籍ストア	＜p＞Medicine is undergoing a silent revolution that promises to transform the way we treat patients. While remarkable strides have been made in understanding disease and developing drugs, each person's individual response to treatments remains a complex mystery to unravel.＜/p＞＜p＞This book seeks to explore one of the most promising areas on this journey towards personalized medicine: pharmacogenomics. By studying the interactions between an individual's genes and drug response, pharmacogenomics allows us to understand why each person responds differently to a given treatment and how we can tailor therapies to maximize their effectiveness and minimize side effects. .＜/p＞＜p＞Throughout these pages, we will delve into a fascinating universe of scientific discoveries, genetic concepts and clinical applications of pharmacogenomics. We will explore the challenges and opportunities this discipline offers, from gene expression analysis to personalized therapy in fetal medicine and rare diseases.＜/p＞＜p＞We will understand how pharmacogenomics can contribute to reducing health costs and how the identification of genes related to drug response can open doors to the development of more effective therapies. We will also tackle the ethical and practical challenges associated with implementing pharmacogenomics in different areas of medicine.＜/p＞＜p＞Along this journey, we will meet dedicated researchers, visionary physicians and patients who have benefited from the personalized approach to medicine. We will discover methods used in pharmacogenomics and explore their applications in fields as diverse as palliative medicine, anesthesiology, dentistry and regenerative medicine.＜/p＞＜p＞This book seeks not only to share knowledge, but also to stimulate reflection and dialogue about the future of medicine. I hope that you, the reader, will find in these pages a guide to understanding and enchanting yourself with the revolutionary potential of pharmacogenomics and personalized therapy.＜/p＞＜p＞The journey starts now. Welcome to a world where genetics meets medicine in a unique and transformative way.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	1,735円
Applying Pharmacogenomics in Therapeutics【電子書籍】楽天Kobo電子書籍ストア	＜p＞Recent advances in high-throughput gene sequencing and other omics biotechnologies have served as a springboard for the field of pharmacogenomics. Pharmacogenomics is now generally accepted as the major determinant of variable drug safety, efficacy, and cost-effectiveness. Therefore, widespread use of pharmacogenomics for patient care has become a＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	8,278円
Pharmacogenomics Challenges and Opportunities in Therapeutic Implementation【電子書籍】楽天Kobo電子書籍ストア	＜p＞＜em＞Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation, Second Edition＜/em＞, provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of pharmacogenomics from academic, regulatory, pharmaceutical, socio-ethical and economic perspectives. While emphasis is on the limitations in moving the science into drug development and direct therapeutic applications, this book also focuses on clinical areas with successful applications and important initiatives that have the ability to further advance the discipline. New chapters cover important topics such as pharmacogenomic data technologies, clinical testing strategies, cost-effectiveness, and pharmacogenomic education and practice guidelines. The importance of ethnicity is also discussed, which highlights phar,acogenomic diversity across Latin American populations.With chapters written by interdisciplinary experts and insights into the future direction of the field, this book is an indispensable resource for academic and industry scientists, graduate students and clinicians engaged in pharmacogenomics research and therapeutic implementation.＜/p＞＜ul＞＜li＞Provides viewpoints that focus on the scientific and translational challenges and opportunities associated with advancing the field of pharmacogenomics＜/li＞＜li＞Highlights progress in both the research and clinical areas of pharmacogenomics, as well as relevant implementation experience, challenges, and perspectives on direct-to-consumer genetic testing＜/li＞＜li＞Includes, where applicable, discussion points, review questions, and cases for self-assessment purposes and to facilitate in-depth discussion＜/li＞＜/ul＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	12,357円
Pharmacogenomics An Introduction and Clinical Perspective【電子書籍】[ Joseph S. Bertino ] 楽天Kobo電子書籍ストア	＜h4＞A COMPLETE INTRODUCTORY TEXT TO THE FIELD OF PHARMACOGENOMICS＜/h4＞＜p＞The only pharmacogenomics resource to feature a global author team comprised of PharmDs, MDs, PhDs and social scientists, ＜em＞Pharmacogenomics＜/em＞ offers an essential, highly accessible survey of this dynamic discipline. You will find thorough coverage of all need-to-know topics, from individual molecules to systemic diseases, plus an examination of the latest technologies that are constantly reshaping the field. ＜em＞Pharmacogenomics＜/em＞ is cohesively organized into two sections, the first of which reviews basic aspects of pharmacogenomics, including ethics, regulatory, science, and drug metabolism, along with a "mini" course in molecular genetics and testing. The second section highlights the practical application of pharmacogenomics in cardiovascular medicine, immunology, neurology, and other specialties.＜/p＞＜p＞＜strong＞FEATURES＜/strong＞＜/p＞＜ul＞＜li＞Important overview of general pharmacogenomics and pharmacogenetics concepts, including genetic variation in signal transduction and targets, plus a review of the genetic concepts of pharmacogenomics＜/li＞＜li＞Discussion of regulatory considerations in pharmacogenomics＜/li＞＜li＞Focus on the role of health care professionals along with a review of related privacy issues, as well as broader ethical, legal, and social considerations＜/li＞＜li＞In-depth chapters on drug metabolism and transporters＜/li＞＜li＞Practical, step-by-step guidance on public access to pharmacogenomic testing and patient counseling＜/li＞＜li＞Up-to-date coverage of non-genetic influences on pharmacogenomics＜/li＞＜li＞Emphasis on gene-drug interactions＜/li＞＜li＞Numerous tables and figures＜/li＞＜li＞Chapter-ending references＜/li＞＜li＞Concise learning objectives at the beginning of each chapter＜/li＞＜li＞Case studies to familiarize you with the clinical relevance of pharmacogenomics in each specialty＜/li＞＜/ul＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	11,297円
Clinical Challenges in Therapeutic Drug Monitoring Special Populations, Physiological Conditions and Pharmacogenomics【電子書籍】楽天Kobo電子書籍ストア	＜p＞＜em＞Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions and Pharmacogenomic＜/em＞s focuses on critical issues in therapeutic drug monitoring including special requirements of therapeutic drug monitoring important to special populations (infants and children, pregnant women, elderly patients, and obese patients). The book also covers issues of free drug monitoring and common interferences in using immunoassays for therapeutic drug monitoring.＜/p＞＜p＞This book is essential reading for any clinician, fellow, or trainee who wants to gain greater insight into the process of therapeutic drug monitoring for individual dosage adjustment and avoiding drug toxicity for certain drugs within a narrow therapeutic window. The book is written specifically for busy clinicians, fellows, and trainees who order therapeutic drug monitoring and need to get more familiar with testing methodologies, issues of interferences, and interpretation of results in certain patient populations.＜/p＞＜ul＞＜li＞Offers busy clinicians, pathologists, and trainees a concise resource on the key aspects and critical issues in therapeutic drug monitoring＜/li＞＜li＞Focuses on patient populations such as infants and children, pregnant women, elderly patients, and obese patients, who have special requirements in therapeutic drug monitoring＜/li＞＜li＞Explores special topics in therapeutic drug monitoring including free drug monitoring and common immunoassay interference＜/li＞＜li＞Explains how individual dosage adjustments can prevent drug toxicity for certain drugs within a narrow therapeutic window＜/li＞＜/ul＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	4,939円
Pharmacogenomics in Psychiatry【電子書籍】楽天Kobo電子書籍ストア	＜p＞In recent years, there have been major developments in the fields of pharmacogenetics and pharmacogenomics, with the potential to make drug treatments in psychiatric medicine more effective. However, improvements in drug efficacy and tolerability, as well as finding the optimal dosage, can only be realized if in vivo mechanisms of drug action and ADME (absorption, distribution, metabolism, excretion) processes (pharmacokinetics) of psychopharmacological agents are better understood. In this volume, current progress and perspectives in pharmacogenetic testing of drug-metabolizing enzymes, drug transporters and other drug targets involved in the response to psychotropic agents are described extensively. This provides a timely overview of what has been achieved in the area of psychiatric pharmacogenomics alongside some promising directions and perspectives for future research.Psychiatrists, general medical doctors as well as pharmacologists and clinical pharmacologists will find new insights into the development and applications of pharmacogenomics in psychiatry.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	8,512円
Pharmacogenomics: A Primer for Clinicians【電子書籍】[ Jerika T. Lam ] 楽天Kobo電子書籍ストア	＜p＞＜strong＞An invaluable resource to the rapidly emerging field of pharmacogenomicsーcomplete with case studies, clinical pearls, and treatment recommendations＜/strong＞＜/p＞＜p＞The aim of pharmacogenomics is to improve personalized medicine by taking into account how genes affect an individual’s tolerability and response to drugs. Approaching pharmacogenomics from the current clinical, scientific, and implementation perspectives, this guide serves as an invaluable evidence-based resource to the subject. Reflecting the shift from genetics to genomics in the pharmaceutical sphere, the book covers pharmacogenomics fundamentals; genotyping tests and evidence; clinical implementation; ethical, legal, and social issues; and more. You’ll also find illuminating case scenarios, clinical pearls, and evidence-based recommendations for treatments and alternatives based on CPIC, PharmGKB, and FDA guidelines.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	10,216円
Principles of Pharmacogenetics and Pharmacogenomics【電子書籍】楽天Kobo電子書籍ストア	＜p＞The study of pharmacogenetics and pharmacogenomics focuses on how our genes and complex gene systems influence our response to drugs. Recent progress in clinical therapeutics has led to the discovery of new biomarkers that make it technically easier to identify groups of patients which are more or less likely to respond to individual therapies. The aim is to improve personalised medicine - not simply to prescribe the right medicine, but to deliver the right drug at the right dose at the right time. This textbook brings together leading experts to discuss the latest information on how human genetics impacts drug response phenotypes. It presents not only the basic principles of pharmacogenetics, but also clinically valuable examples that cover a broad range of specialties and therapeutic areas. This textbook is an invaluable introduction to pharmacogenetics and pharmacogenomics for health care professionals, medical students, pharmacy students, graduate students and researchers in the biosciences.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	13,246円
Pharmacogenomics in Precision Medicine From a Perspective of Ethnic Differences【電子書籍】楽天Kobo電子書籍ストア	＜p＞This book provides an introduction to the principles of pharmacogenomics and precision medicine, followed by the pharmacogenomics aspects of major therapeutic areas such as cardiovascular disease, cancer, organ transplantation, psychiatry, infection, antithrombotic drugs. It also includes genotyping technology and therapeutic drug monitoring in Pharmacogenomics; ethical, Legal and Regulatory Issues; cost-effectiveness of pharmacogenetics-guided treatment; application of pharmacogenomics in drug discovery and development and clinical Implementation of Pharmacogenomics for Personalized Precision Medicine. The contributors of Pharmacogenomics in Precision Medicine come from a team of experts, including professors from academic institutions and practitioner from hospital. It will give an in-depth overview of the current state of pharmacogenomics in drug therapy for all health care professionals and graduate students in the era of precision medicine.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	12,154円
Pharmacogenomics in Drug Discovery and Development【電子書籍】楽天Kobo電子書籍ストア	＜p＞This new edition offers a state-of-the-art and integrative vision of pharmacogenomics by exploring new concepts and practical methodologies focusing on disease treatments, from cancers to cardiovascular and neurodegenerative disorders and more. The collection of these theoretical and experimental approaches facilitates problem-solving by tackling the complexity of personalized drug discovery and development. Written by leading experts in their fields for the highly successful ＜em＞Methods in Molecular Biology＜/em＞ series, the book aims to provide across-the-board resources to support the translation of pharmacogenomics into better individualized health care.＜/p＞＜p＞Authoritative and up-to-date, ＜em＞Pharmacogenomics in Drug Discovery and Development, Third Edition＜/em＞ aims to aid researchers in approaching the challenges in pharmacogenomics and personalized medicine with the introduction of these novel ideas and cutting-edge methodologies.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	19,447円
Pharmacogenomics in Clinical Therapeutics【電子書籍】楽天Kobo電子書籍ストア	＜p＞Pharmacogenomics is the basis of personalized medicine which will be the medicine of the future. Through both reducing the numbers of adverse drug reactions and improving the use of existing drugs in targeted populations, pharmacogenomics represents a real advance on traditional therapeutic drug monitoring.＜/p＞＜p＞＜em＞Pharmacogenomics in Clinical Therapeutics＜/em＞ provides an introduction to the principles of pharmacogenomics before addressing the pharmacogenomic aspects of key therapeutic areas such as warfarin therapy, cancer chemotherapy, therapy with immunosuppressants, antiretroviral therapy, and psychoactive drugs. It also includes methods of pharmacogenomic testing and the pharmacogenomic aspects of drug?drug interactions.＜/p＞＜p＞From a team of expert contributors, ＜em＞Pharmacogenomics in Clinical Therapeutics＜/em＞ is a comprehensive overview of the current state of pharmacogenomics in pharmacotherapy for all clinicians, pharmacologists and clinical laboratory professionals. It is also a guide for practicing clinicians and health care professionals to the basic principles of pharmacogenomics, laboratory tests currently available to aid clinicians, and the future promise of this developing field.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	18,170円
Pharmacogenomics in Clinical Practice【電子書籍】楽天Kobo電子書籍ストア	＜p＞This book provides a practically applicable guide to the applications of pharmogenomics across medicine. Background information is provided on the mechanisms associated with membrane transporters, drug-metabolizing enzymes and their importance in pharmagenomics. Detailed guidance is subsequently presented on how to apply these techniques in disciplines including cardiology, gastroenterology, oncology, transplantation surgery, infectious diseases, anesthesia and analgesia, neurology, psychiatry, primary care, and public health. Clear easy-to-follow instructions are given on how to use big data technologies and public health databases in day-to-day clinical practice.＜/p＞＜p＞＜em＞Pharmacogenomics in Clinical Practice＜/em＞ concisely covers how pharmacogenomic technologies and techniques can be applied in daily medical practice. It is therefore an ideal up-to-date resource for any medical practitioner, trainee or researcher across all medical disciplines whowant to better understand how to use these techniques.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	13,369円
【中古】【未使用・未開封品】Pharmacogenomics in Drug Discovery and Development (Methods in Molecular Biology, 448) AJIMURA-SHOP	【中古】【未使用・未開封品】Pharmacogenomics in Drug Discovery and Development (Methods in Molecular Biology, 448)【メーカー名】【メーカー型番】【ブランド名】Humana Biological Sciences, Chemistry, Bioinformatics, Chemistry, Genetics, Pharmacology, Amazon Student ポイント還元(洋書), Search Inside The Book, Amazonアプリキャンペーン対象商品(洋書), 洋書（アダルト除く） Yan, Qing: Editor【商品説明】Pharmacogenomics in Drug Discovery and Development (Methods in Molecular Biology, 448)【注意】こちらは輸入品となります。当店では初期不良に限り、商品到着から7日間は返品を受付けております。こちらは当店海外ショップで一般の方から買取した未使用・未開封品です。買取した為、中古扱いとしております。他モールとの併売品の為、完売の際はご連絡致しますのでご了承ください。ご注文からお届けまで1、ご注文⇒ご注文は24時間受け付けております。2、注文確認⇒ご注文後、当店から注文確認メールを送信します。3、当店海外倉庫から当店日本倉庫を経由しお届けしますので10〜30営業日程度でのお届けとなります。4、入金確認⇒前払い決済をご選択の場合、ご入金確認後、配送手配を致します。5、出荷⇒配送準備が整い次第、出荷致します。配送業者、追跡番号等の詳細をメール送信致します。6、到着⇒出荷後、1〜3日後に商品が到着します。　※離島、北海道、九州、沖縄は遅れる場合がございます。予めご了承下さい。お電話でのお問合せは少人数で運営の為受け付けておりませんので、メールにてお問合せお願い致します。営業時間　月〜金　10:00〜17:00お客様都合によるご注文後のキャンセル・返品はお受けしておりませんのでご了承下さい。	39,204円
Pharmacogenomics: Foundations, Competencies, and the Pharmacists' Patient Care Process【電子書籍】[ David F. Kisor, BS, PharmD, FCP, RPh ] 楽天Kobo電子書籍ストア	＜p＞Pharmacogenomics: Foundations, Competencies, and the Pharmacists’ Patient Care Process provides a basic and clinical foundation for the application of drug-gene interactions in clinical therapeutics. As the field of PGx advances, there is a need for a pharmacy-based, directed resource that can be a reference for practicing pharmacists and student pharmacists. Specific information is presented through “PGx Pearls.” Each of the 17 cases are presented in the context of the PPCP, with “Competency Connections” related to genetics and genomics. Each of the 29 chapters providescontent and objective related questions with the answers provided. Two appendices are included. KEY FEATURES: Connects the clinical application with basic foundational principles of pharmacogenomics Includes pharmacogenomics case studies across therapeutic areas PPCP-focused content that reinforces the pharmacists’ role in pharmacogenomics Ideal for adoption in courses teaching pharmacogenomics and pharmacogenetics Chapter 1. Foundations of Pharmacogenomics Chapter 2. Pharmacogenomics: Drug Exposure and Response Chapter 3. Pharmacists Competencies in Genetics/Genomics Chapter 4. Information Resources for Pharmacogenomics Chapter 5. Implementation of Pharmacogenomics across Practice Settings Chapter 6. The Pharmacists’ Patient Care Process (PPCP) Chapter 7. Cardiology: Clopidogrel/CYP2C19 Case Chapter 8. Cardiology: Simvastatin/SLCO1B1 Case Chapter 9. Cardiology: Warfarin/CYP2C9, VKORC1, CYP4F2 Case Chapter 10. Endocrinology: Glipizide/G6PD Case Chapter 11. Immunology: Tacrolimus/CYP3A5 Case Chapter 12. Infectious Diseases: Abacavir/HLA-B Case Chapter 13. Infectious Diseases: Atazanavir/UGT1A1 Case Chapter 14. Infectious Diseases: Voriconazole/CYP2C19 Case Chapter 15. Neurology: Carbamazepine/HLA-A, HLA-B Case Chapter 16. Neurology: Phenytoin/CYP2C9, HLA-B Case Chapter 17. Oncology: Somatic Disease and Pharmacogenomics Chapter 18. Oncology: Mercaptopurine/TPMT Case Chapter 19. Oncology: Fluorouracil/DPYD Case Chapter 20. Oncology: Rasburicase/G6PD Case Chapter 21. Psychiatry: Amitriptyline/CYP2C19, CYP2D6 Case Chapter 22. Psychiatry: Paroxetine/CYP2D6 Case Chapter 23. Respiratory: Ivacaftor/CFTR Case Chapter 24. Rheumatology/Musculoskeletal Pain: Allopurinol/HLA-B Case Chapter 25. Rheumatology/Musculoskeletal Pain: Azathioprine/TPMT, Celecoxib/CYP2C9 Case Chapter 26. Rheumatology/Musculoskeletal Pain: Codeine/CYP2D6 Case Chapter 27. Pharmacogenomics Testing Chapter 28. Pharmacogenomics in Ethical and Social Contexts Chapter 29. Pharmacogenomics and Secondary/ Incidental Findings Appendix 1: Competency Connections Appendix 2: Glossary＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	7,472円
Pharmacogenomics Foundations, Competencies, and the Pharmacists’ Patient Care Process, Second Edition【電子書籍】楽天Kobo電子書籍ストア	＜p＞Pharmacogenomics: Foundations, Competencies, and the Pharmacists’ Patient Care Process, Second Edition provides a basic and clinical foundation for the application of drug-gene interactions in clinical therapeutics. As the field of PGx advances and changes rapidly, there is a need for a regularly updated, pharmacy-focused resource that can be a reference for practicing pharmacists and student pharmacists in the context of the Pharmacists’ Patient Care Process (PPCP). Specific information is presented through “PGx Pearls.” Each of the 20 cases are presented in the context of the PPCP, with “Competency Connections” related to updated pharmacists’ competencies in genetics and genomics. Each chapter provides content and objective-related questions with the answers provided.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	8,006円
Quantitative Methods for Precision Medicine Pharmacogenomics in Action【電子書籍】[ Rongling Wu ] 楽天Kobo電子書籍ストア	＜p＞Modern medicine is undergoing a paradigm shift from a "one-size-fits-all" strategy to a more precise patient-customized therapy and medication plan. While the success of precision medicine relies on the level of pharmacogenomic knowledge, dissecting the genetic mechanisms of drug response in a sufficient detail requires powerful computational tools. ＜em＞＜strong＞Quantitative Methods for Precision Medicine: Pharmacogenomics in Action＜/strong＞＜/em＞ presents the advanced statistical methods for mapping pharmacogenetic control by integrating pharmacokinetic and pharmacodynamic principles of drug-body interactions. Beyond traditional reductionist-based statistical genetic approaches, statistical formulization in this book synthesizes elements of multiple disciplines to infer, visualize, and track how pharmacogenes interact together as an intricate but well-coordinated system to mediate patient-specific drug response.＜/p＞＜p＞＜strong＞Features:＜/strong＞＜/p＞＜ul＞＜li＞Functional and systems mapping models to characterize the genetic architecture of multiple medication processes＜/li＞＜li＞Statistical methods for analyzing informative missing data in pharmacogenetic association studies＜/li＞＜li＞Functional graph theory of inferring genetic interaction networks from association data＜/li＞＜li＞Leveraging the concept of epistasis to capture its bidirectional, signed and weighted properties＜/li＞＜li＞Modeling gene-induced cell-cell crosstalk and its impact on drug response＜/li＞＜li＞A graph model of drug-drug interactions in combination therapies＜/li＞＜li＞Critical methodological issues to improve pharmacogenomic research as the cornerstone of precision medicine＜/li＞＜/ul＞＜p＞This book is suitable for graduate students and researchers in the fields of biology, medicine, bioinformatics and drug design and delivery who are interested in statistical and computational modelling of biological processes and systems. It may also serve as a major reference for applied mathematicians, computer scientists, and statisticians who attempt to develop algorithmic tools for genetic mapping, systems pharmacogenomics and systems biology. It can be used as both a textbook and research reference. Professionals in pharmaceutical sectors who design drugs and clinical doctors who deliver drugs will also find it useful.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	8,945円
Handbook of Pharmacogenomics and Stratified Medicine【電子書籍】楽天Kobo電子書籍ストア	＜p＞＜em＞Handbook of Pharmacogenomics and Stratified Medicine＜/em＞ is a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right time. It is designed to provide a detailed, but accessible review of the entire field from basic principles to applications in various diseases. The chapters are written by international experts to allow readers from a wide variety of backgrounds, clinical and non-clinical (basic geneticists, pharmacologists, clinicians, trialists, industry personnel, ethicists) to understand the principles underpinning the progress in this area, the successes, failures and the challenges ahead. To be accessible to the widest range of readers, the clinical application section introduces the disease process, existing therapies, followed by pharmacogenomics and stratified medicine details.＜/p＞＜p＞Medicine is the cornerstone of modern therapeutics prescribed on the basis that its benefit should outweigh its risk. It is well known that people respond differently to medications and in many cases the risk-benefit ratio for a particular drug may be a gray area. The last decade has seen a revolution in genomics both in terms of technological innovation and discovering genetic markers associated with disease. In parallel there has been steady progress in trying to make medicines safer and tailored to the individual. This has occurred across the whole spectrum of medicine, some more than others. In addition there is burgeoning interest from the pharmaceutical industry to leverage pharmacogenomics for more effective and efficient clinical drug development.＜/p＞＜ul＞＜li＞Provides clinical and non-clinical researchers with practical information normally beyond their usual areas of research or expertise＜/li＞＜li＞Includes an basic principles section explaining concepts of basic genetics, genetic epidemiology, bioinformatics, pharmacokinetics and pharmacodynamics＜/li＞＜li＞Covers newer technologies? next generation sequencing, proteomics, metabolomics＜/li＞＜li＞Provides information on animal models, lymphoblastoid cell lines, stem cells＜/li＞＜li＞Provides detailed chapters on a wide range of disease conditions, implementation and regulatory issues＜/li＞＜li＞Includes chapters on the global implications of pharmacogenomics＜/li＞＜/ul＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	24,320円
洋書 Paperback, Concepts in Pharmacogenomics Glomarket	* We ship internationally, so do not use a package forwarding service. We cannot ship to a package forwarding company address because of the Japanese customs regulation. If it is shipped and customs office does not let the package go, we do not make a refund. 【注意事項】 * 特に注意してください。 * ・個人ではない法人・団体名義での購入はできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。・お名前にカタカナが入っている場合法人である可能性が高いため当店システムから自動保留します。カタカナで記載が必要な場合はカタカナ変わりローマ字で記載してください。・お名前またはご住所が法人・団体名義（XX株式会社等）、商店名などを含めている場合、または電話番号が個人のものではない場合、税関から法人名義でみなされますのでご注意ください。・転送サービス会社への発送もできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 * ・注文後品切れや価格変動でキャンセルされる場合がございますので予めご了承願います。・当店でご購入された商品は、原則として、「個人輸入」としての取り扱いになり、すべてニュージャージからお客様のもとへ直送されます。・ご注文後、30営業日以内(通常2~3週間)に配送手続きをいたします。配送作業完了後、2週間程度でのお届けとなります。・まれに商品入荷状況や国際情勢、運送、通関事情により、お届けが2ヶ月までかかる場合がありますのでお急ぎの場合は注文をお控えください。・個人輸入される商品は、すべてご注文者自身の「個人使用・個人消費」が前提となりますので、ご注文された商品を第三者へ譲渡・転売することは法律で禁止されております。・関税・消費税が課税される場合があります。詳細はこちらをご確認下さい。PC販売説明文	21,986円
Pharmacogenomics From Discovery to Clinical Implementation【電子書籍】楽天Kobo電子書籍ストア	＜p＞＜em＞Pharmacogenomics: From Discovery to Clinical Implementation＜/em＞ is a complete reference aimed at building a solid foundation of the key concepts in this fast-moving knowledge area.＜/p＞＜p＞The editors lined up a group of worldwide experts to contribute to the book. Following a consistent chapter structure, the authors cover the foundational aspects of pharmacogenomics in the first four chapters of the book that include basic concepts, drug metabolism, drug discovery and development, and testing. The second part of the book is dedicated to detailed studies of key health conditions and the potential therapeutic applications of pharmacogenomics. Diseases covered include diabetes, cardiovascular diseases, psychiatric disease, cancer, pulmonary and respiratory diseases, viral diseases, gastroenterology, autoimmune diseases, immunosuppressants, and, finally, an overview of computational resources.＜/p＞＜p＞＜em＞Pharmacogenomics: From Discovery to Clinical Implementation＜/em＞ is the perfect resource for pharmaceutical science graduate students to learn the key concepts of the area. Researchers and graduate students in the related fields of Genetics, pharmacoepidemiology, molecular biology, and medicinal chemistry will also benefit of the structured approach of the book.＜/p＞＜ul＞＜li＞Provides an in-depth review of pharmacogenomics and its role in drug discovery/metabolism and its clinical impacts＜/li＞＜li＞Describes the practice of pharmacogenomics in the treatment of diabetes, cancers, cardiovascular diseases, psychiatric disorders, pulmonary diseases, infectious, gastroenterology, and autoimmune diseases＜/li＞＜li＞Uses a consistent chapter structure to support understanding of the fundamental concepts in the area＜/li＞＜/ul＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	17,301円
Pharmacogenomics of Human Drug Transporters Clinical Impacts【電子書籍】[ Toshihisa Ishikawa ] 楽天Kobo電子書籍ストア	＜p＞＜strong＞Sets the foundation for safer, more effective drug therapies＜/strong＞＜/p＞＜p＞With this book as their guide, readers will discover how to apply our current understanding of the pharmacogenomics of drug transporters to advance their own drug discovery and development efforts. In particular, the book explains how new findings in the field now enable researchers to more accurately predict drug interactions and adverse drug reactions. Moreover, it sets the foundation for the development of drug therapies that are tailored to an individual patient's genetics.＜/p＞＜p＞＜em＞Pharmacogenomics of Human Drug Transporters＜/em＞ serves as a comprehensive guide to how transporters regulate the absorption, distribution, and elimination of drugs in the body as well as how an individual's genome affects those processes. The book's eighteen chapters have been authored by a team of leading pioneers in the field. Based on their own laboratory and clinical experience as well as a thorough review of the literature, these authors explore all facets of drug transporter pharmacogenomics, including:＜/p＞＜ul＞＜li＞Individual drug transporters and transporter families and their clinical significance＜/li＞＜li＞Principles of altered drug transport in drug drug interactions, pharmacotherapy, and personalized medicine＜/li＞＜li＞Emerging new technologies for rapid detection of genetic polymorphisms＜/li＞＜li＞Clinical aspects of genetic polymorphisms in major drug transporter genes＜/li＞＜li＞Future research directions of drug transporter pharmacogenomics and the prospect of individualized medicine＜/li＞＜/ul＞＜p＞＜em＞Pharmacogenomics of Human Drug Transporters＜/em＞ opens the door to new drug discovery and development breakthroughs leading to safer and more effective customized drug therapies.The book is recommended for pharmaceutical scientists, biochemists, pharmacologists, clinicians, and genetics and genomics researchers.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	20,397円
Immunopharmacogenomics【電子書籍】楽天Kobo電子書籍ストア	＜p＞This book proposes immunogenomics, or immunopharmacogenomics, as the next-generation big science to uncover the role that the immune system plays in the pathogenesis of many diseases, by summarizing the importance of the deep sequencing of T-cell and B-cell receptors. Immunogenomics/immunopharmacogenomics, a genetic characterization of the immune system made possible by next-generation sequencing (NGS), will be important for the further understanding of the pathogenesis of various disease conditions. Abnormal immune responses in the body lead to development of autoimmune diseases and food allergies. Rejection of recipient cells and tissues, as well as severe immune reactions to donor cells, is also the result of uncontrolled immune responses in the recipient body. There have been many reports indicating that activated immune responses caused by the interaction of drugs and HLA are present in drug-induced skin hypersensitivity and liver toxicity. The importance of the host immune responses has been recognized in cancer treatments, not only for immunotherapy but also for cytotoxic agents and molecular targeted drugs. Hence, characterization of the T-cell receptor and B-cell receptor repertoire by means of NGS deep sequencing will ultimately make possible the identification of the molecular mechanisms that underlie various diseases and drug responses. In addition, this approach may contribute to the identification of antigens associated with the onset or progression of autoimmune diseases as well as food allergies. Although the germline alterations and somatic mutations have been extensively analyzed, changes or alterations of the immune responses during the course of various disease conditions or during various treatments have not been analyzed. It is also clear that computational analyses to draw meaningful inferences of functional recognition receptors on the immune cells remain a huge challenge.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちらをクリックして下さい。 ※このページからは注文できません。	12,154円