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73件中 1件 - 30件
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商品 | 説明 | 価格 |

Advances in Pharmacokinetics and Pharmacodynamics【電子書籍】
楽天Kobo電子書籍ストア
|
<p>This book provides a concise overview of recent advances in Pharmacokinetics (PK) and Pharmacodynamics (PD). The pharmacokinetics section covers the state of the art in Physiologically Based Pharmacokinetic (PBPK) modeling (Chapter 1) as well as the assessment of food effect on drug absorption using PBPK modeling (Chapter 2). Chapters 3 and 4 describe the recent development of Physiologically Based Finite Time Pharmacokinetic (PBFTPK) models and their applications to pharmacokinetic data. The pharmacodynamics section focuses on PK/PD modeling. Chapter 5 provides an overview of PK/PD modeling and simulation in clinical practice and studies. Chapter 6 deals with the subject/physiology variability issue encountered in PK/PD studies, while Chapter 7 reviews the influence of clinical pharmacology in the modernization of drug development and regulation. This book is an essential reference for pharmaceutical scientists.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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13,369円
|

Pharmacokinetics: A Tutorial Study Guide Science Textbook Series【電子書籍】[ Nicoladie Tam ]
楽天Kobo電子書籍ストア
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<p>"Pharmacokinetics" is a book chapter of the college-level textbook for the book volume in the Principles of Neuropsychopharmacology course. It is a part of the Science Textbook Series authored by Nicoladie Tam, Ph.D. that also includes the Principles of Biology course.</p> <p>This book is written with specific pedagogical considerations to facilitate students' learning. It applies the proven best practices to motivate students in learning. It uses multiple pedagogical methodologies to engage students in active learning by participating in the knowledge acquisition process. It stimulates the curiosity of students by asking them questions and answering them immediately. It guides the students in their comprehension of knowledge by using examples and by giving them detailed explanations following the answers.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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350円
|

Pharmacokinetics in Everyday Clinical Practice【電子書籍】[ Federico Pea ]
楽天Kobo電子書籍ストア
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<p>This book provides a practical introduction to the main concepts of pharmacokinetics and how they can be applied in clinical settings, without using complicated mathematical equations. Essential information on approaches to drug-dosing and monitoring in special populations, including patients with renal and hepatic diseases and elderly patients, are given. Charts, illustrations and examples of calculations are added to clarify concepts and terminology of pharmacokinetics. It’s a guide for students and clinicians who want clear, useful guidance to the basic principles of pharmacokinetics and their application into clinical practice.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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1,758円
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Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications【電子書籍】[ Hartmut Derendorf ]
楽天Kobo電子書籍ストア
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<p>Updated with the latest clinical advances, Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics, Fifth Edition , explains the relationship between drug administration and drug response, taking a conceptual approach that emphasizes clinical application rather than science and mathematics. Bringing a real-life perspective to the topic, the book simplifies concepts and gives readers the knowledge they need to better evaluate drug applications.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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17,733円
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Applied Clinical Pharmacokinetics and Pharmacodynamics of Psychopharmacological Agents【電子書籍】
楽天Kobo電子書籍ストア
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<p>This book is a comprehensive resource on psychotropic medications, detailing the latest methods for defining their characteristics, their use in different patient populations, and drug-drug interactions; an important collection of information forclinicians, students, researchers, and members of the pharmaceutical industry alike.</p> <p>The first section provides the foundational principles of these drugs. Mathematical modeling of parameters that affect their entryto,and exit from, the central nervous system (CNS) compartment are presented on an individual basis and then applied to target populations with specific disease states. Methods and characteristics that inform the transfer of these drugs from the laboratory bench to use in patient care are discussed, including imaging techniques, genetics and physiological barriers, such as the blood-brain barrier. The second section describes the characteristics of specific agents,nominally arranged intodifferent therapeutic categories andwith reference crossover use in different disease states. The pharmacologic characteristics of different drug formulations are explored in the context of their ability to improve patient adherence. The third section focuses on drug-drug interactions.Psychotropic medications from different categories are frequently prescribed together,or alongside medications used to treat comorbid conditions, and the information provided is directly relevant to the clinic, as a result.</p> <p>The clinical application of pharmacokinetics and pharmacodynamics of CNS agents has made significant progress over the past 50 years and new information is reported by numerous publications in psychiatry, neurology, and pharmacology.Our understanding of the interrelationship between these medications, receptors, drug transporters, as well as techniques for measurement and monitoring their interactions,isfrequently updated. However, with information presented on a host of different platforms, and in differentformats, obtaining the full picture can be difficult. This title aims to collate this information into a single source that can be easily interpreted and applied towards patient care by the clinical practitioner, and act as a reference for all others who have an interest in psychopharmacological agents.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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14,585円
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The ADME Encyclopedia A Comprehensive Guide on Biopharmacy and Pharmacokinetics【電子書籍】
楽天Kobo電子書籍ストア
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<p><em>The ADME Encyclopedia</em> covers pharmacokinetic phenomena (Absorption, Distribution, Metabolism and Excretion processes) and their relationship with the design of pharmaceutical carriers and the success of drug therapies. It covers both basic and advanced knowledge, serving as introductory material for students of biomedical careers and also as reference, updated material for graduates and professionals working in any field related to pharmaceutical sciences (medicine, pharmaceutical technology, materials science, medicinal chemistry).</p> <p>Structured as alphabetically ordered entries with cross-references, the Encyclopedia not only provides basic knowledge on ADME processes, but also detailed entries on some advanced subjects such as drug transporters, last generation pharmaceutical carriers, pharmacogenomics, personalized medicine, bioequivalence studies, biowaivers, biopharmaceuticals, gene delivery, pharmacometrics, pharmacokinetic drug interactions or in silicoand in vitro assessment of ADME properties</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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115,471円
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Computational Pharmacokinetics【電子書籍】[ Anders Kallen ]
楽天Kobo電子書籍ストア
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<p>Being that pharmacokinetics (PK) is the study of how the body handles various substances, it is not surprising that PK plays an important role in the early development of new drugs. However, the clinical research community widely believes that mathematics in some way blurs the true meaning of PK. Demonstrating that quite the opposite is true, Computational Pharmacokinetics outlines the fundamental concepts and models of PK from a mathematical perspective based on clinically relevant parameters.</p> <p>After an introductory chapter, the book presents a noncompartmental approach to PK and discusses the numerical analysis of PK data, including a description of an absorption process through numerical deconvolution. The author then builds a simple physiological model to better understand PK volumes and compares this model to other methods. The book also introduces compartmental models, discusses their limitations, and creates a general-purpose type of model. The final chapter looks at the relationship between drug concentration and effect, known as PK/pharmacodynamics (PD) modeling.</p> <p>With both a solid discussion of theory and the use of practical examples, this book will enable readers to thoroughly grasp the computational factors of PK modeling.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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13,703円
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Drug Disposition and Pharmacokinetics From Principles to Applications【電子書籍】[ Stephen H. Curry ]
楽天Kobo電子書籍ストア
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<p>This is an authoritative, comprehensive book on the fate of drug molecules in the body, including implications for pharmacological and clinical effects. The text provides a unique, balanced approach, examining the specific physical and biological factors affecting the absorption, distribution, metabolism and excretion of drugs, together with mathematical assessment of the concentrations in plasma and body fluids. Understanding the equations requires little more than a basic knowledge of algebra, laws of indices and logarithms, and very simple calculus. A companion web site contains additional illustrations, further equations and numerous worked examples.</p> <p>Whilst this book has its roots in the highly acclaimed book of the same name, written by Stephen Curry nearly thirty years ago, it is essentially a new book having been restructured and largely rewritten. This readable and informative book is an invaluable resource for professionals and students needing to develop a rational approach to the investigation and application of drugs.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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11,550円
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Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems【電子書籍】
楽天Kobo電子書籍ストア
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<p>A reference is needed that addresses the recent progress in aspects of PK/PD methods and developments of nanoparticles for novel drug delivery systems. No other consolidated published reference discusses the PK/PD study of nanoparticle drug delivery systems. This book discusses the advantages of nanoparticle drug delivery systems (NPDDS) in enhancing the pharmacokinetics of many drugs that are not easily metabolized or that obtain the desired therapeutic effect with minimum toxicity. The authors provide an overview of biodistribution with a focus on polymer and lipid nanoparticles.</p> <p>This thorough reference is divided into three parts: Modelling, Specific carries and their potential to treat specific diseases.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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34,033円
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Handbook of Comparative Pharmacokinetics and Residues of Veterinary Therapeutic Drugs【電子書籍】[ Arthur L. Craigmill ]
楽天Kobo電子書籍ストア
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<p>Handbook of Comparative Pharmacokinetics and Residues of Veterinary Therapeutic Drugs is a unique compilation of comparative pharmacokinetic data for veterinary therapeutic drugs. The book features an excellent introductory chapter on basic veterinary pharmacokinetics and includes pharmacological data taken from hundreds of primary research references. These data are presented in standardized units and are arranged in conveniently organized tables so that comparisons between data can be made easily. Much of the data is new and was taken from articles in which data was not subjected to pharmacokinetic analysis.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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46,757円
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A Short Guide to Clinical Pharmacokinetics SHORT GT CLINICAL PHARMACOKINE [ Krishnaveni Manubolu ]
楽天ブックス
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SHORT GT CLINICAL PHARMACOKINE Krishnaveni Manubolu Raveesha Peeriga K. B. Chandrasekhar SPRINGER2024 Hardcover 2024 English ISBN:9789819742820 洋書 Computers & Science(コンピューター&科学) Science
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54,560円
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Pharmacokinetics and Metabolism in Drug Design【電子書籍】[ Raimund Mannhold ]
楽天Kobo電子書籍ストア
|
<p>In this new edition of a bestseller, all the contents have been brought upto-date by addressing current standards and best practices in the assessment and prediction of ADMET properties. Although the previous chapter layout has been retained, substantial revisions have been made, with new topics such as pro-drugs, active metabolites and transporters covered in detail in a manner useful to the Drug Discovery scientist. The authors discuss the parameters and processes important for the absorption, distribution and retention of drug compounds in the body, plus the potential problems created by their transformation into toxic byproducts.</p> <p>While aimed at all those dealing professionally with the development and application of pharmaceutical substances, the readily comprehensible style makes this book equally suitable for students of pharmacy and related subjects. Uniquely comprehensive, the book relates physicochemistry and chemical structure to pharmacokinetic properties and ultimately drug efficacy and safety.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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19,940円
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Winter's Basic Clinical Pharmacokinetics【電子書籍】[ Beringer, Paul ]
楽天Kobo電子書籍ストア
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<p>Popular among students and clinicians for its easy-to-read, case-study format, Winter’s Basic Clinical Pharmacokinetics, 7th Edition, clarifies complex concepts to help you confidently apply pharmacokinetics and therapeutic drug monitoring to patient care. This straightforward text is divided into two parts, reviewing basic pharmacokinetic principles in Part I and illustrating the clinical application of these principles to the most commonly encountered problems in Part II. The significantly updated and expanded 7th Edition adds essential coverage of the use of pharmacokinetics in managing obesity, pregnancy, as well as anticoagulation</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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11,714円
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Biopharmaceutics and Pharmacokinetics Considerations【電子書籍】[ Rakesh Kumar Tekade ]
楽天Kobo電子書籍ストア
|
<p>Biopharmaceutics and Pharmacokinetics Considerations examines the history of biopharmaceutics and pharmacokinetics. The book provides a biopharmaceutics and pharmacokinetics approach to addressing issues in formulation development and ethical considerations in handling animals. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biopharmaceutics and pharmacokinetics within drug discovery and drug development. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to study the chemical and physical properties of drugs and the biological effects they produce. - Examines the most recent developments in biopharmaceutics and pharmacokinetics for pharmaceutical sciences - Covers the principles, methodologies and technologies of biopharmaceutics and pharmacokinetics - Focuses on the pharmaceutical sciences, but also encompasses aspects of toxicology, neuroscience, environmental sciences and nanotechnology</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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21,147円
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Biopharmaceutics and Clinical Pharmacokinetics An Introduction, Fourth Edition,【電子書籍】[ Robert E. Notari ]
楽天Kobo電子書籍ストア
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<p>For a decade and a half, Biopharmaceutics and Clinical Pharmacokinetics has been used in theclassrooms around the world as an introductory textbook on biophannaceutics and phannacokinetics. Now, the new Fourth Edition, Revised and Expanded further enhances the preceding editions'proven features, introducing significant advances in clinical pharmacokinetics, pharmacokineticdesign of drugs and dosage forms, and model-independent analyses. Still usable without prior knowledge of calculus or kinetics, this successfully implemented workbookmaintains a carefully graduated "building block" presentation, incorporating sample problemsand exercises throughout for a thorough understanding of the material.Biopharmaceutics and Clinical Pharmacokinetics features a growth-oriented format that systematicallydevelops and interrelates all subject matter .. . introduces basic theory and fields of application... emphasizes model-independent pharmacokinetic analyses ... presents biopharmaceutical aspectsof product design and evaluation .. . offers a unique approach to teaching dosage regimen design andindividualization . .. and considers structural modification of drug molecules for problems associatedwith pharmacokinetics. As a comprehensive coverage of the basic principles and the recent achievements in the field, noother textbook does as much for students of pharmacy, pharmacology, medicinal chemistry, andmedicine, or for scientists who desire a simple but thorough introduction to theory and application.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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19,348円
|

Pharmacokinetics: Basics to Applications【電子書籍】[ Biswajit Mukherjee ]
楽天Kobo電子書籍ストア
|
<p>This textbook covers all the essential elements of pharmacokinetics, from basics to applications. It describes authoritative equations and methods on pharmacokinetic evaluation procedures with their importance. Each chapter of the book is supplemented with numerous illustrations and figures for easy understanding of the subject. The book presents mathematical techniques, step- by-step descriptive equations, and applicable statistical analysis methods for the easy understanding of the topic. Further, it covers the preclinical applications and methods of pharmacokinetic aspects. The book also contains mathematical problems and questions related to pharmacokinetics for students. Special emphasis is on recent pharmacokinetic methods and their applications for managing clinical data and biostatistical approaches based on the current literature. This book is primarily meant for researchers and students from academic institutions and to R&D professionals.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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9,723円
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The Art and Science of Physiologically-Based Pharmacokinetics Modeling【電子書籍】
楽天Kobo電子書籍ストア
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<p>This state-of-the-art text describes the science behind the system and drug-dependent components of PBPK models, its applications in translational and regulatory science, e.g., guiding drug discovery and development, and supporting precision medicine initiatives. To incorporate state-of-the-art knowledge, each chapter is written by leaders in the field and illustrated by clear case studies. Connecting basic and applied science, this book explores the potential of PBPK modeling for improving therapeutics and is designed for a wide audience encompassing graduate students as well as biopharmaceutics scientists and clinical pharmacologists.</p> <p>Features:</p> <ol> <li> <p>Provides a basic understanding of the physiologically-based pharmacokinetic modeling and its applications</p> </li> <li> <p>Assists the reader in understanding product performance to allow for rapid product development and establish bioequivalence</p> </li> <li> <p>Well-constructed content and added value of real examples</p> </li> <li> <p>Illustrates how using available resources via modeling and simulation leads to a reduction in the costs related to drug development, which directly affects the costs to patients</p> </li> </ol>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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22,572円
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Casebook in Clinical Pharmacokinetics and Drug Dosing【電子書籍】[ Henry Cohen ]
楽天Kobo電子書籍ストア
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<h4>A STEP-BY-STEP APPROACH TO DESIGNING ACCURATE DOSING REGIMENS</h4> <p><em>Casebook in Pharmacokinetics and Drug Dosing</em> uses real-life cases to teach pharmacy students, pharmacists, and clinical pharmacists how to apply pharmacokinetics to formulate proper dosing regimens. In order to be as clinically relevant as possible, the book not only discusses drugs with readily available therapeutic serum levels, but places equal emphasis on high-alert agents with narrow therapeutic indexes.</p> <p>Each drug chapter is written by clinical pharmacists who have hands-on experience in drug dosing and includes an overview of the drug’s pharmacology, including:</p> <ul> <li>Indications</li> <li>Mec hanisms of action</li> <li>Toxicities</li> <li>Pharmacokinetics</li> </ul> <p>There is comprehensive review and discussion of each drug's bioavailability, volume of distribution, clearance, half-life, therapeutic drug level monitoring, drug interactions, dosing, and availability. Each chapter is enhanced by numerous patient cases with clear step-by-step answers and explanations. Calculations, equations, and dosing recommendations are provided for each case.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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7,401円
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Drug Delivery Approaches Perspectives from Pharmacokinetics and Pharmacodynamics【電子書籍】[ Bret Berner ]
楽天Kobo電子書籍ストア
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<p><strong>Explore this comprehensive discussion of the application of physiologically- and physicochemical-based models to guide drug delivery edited by leading experts in the field</strong></p> <p><em>Drug Delivery Approaches: Perspectives from Pharmacokinetics and Pharmacodynamics</em> delivers a thorough discussion of drug delivery options to achieve target profiles and approaches as defined by physical and pharmacokinetic models. The book offers an overview of drug absorption and physiological models, chapters on oral delivery routes with a focus on both PBPK and multiple dosage form options. It also provides an explanation of the pharmacokinetics of the formulation of drugs delivered by systemic transdermal routes.</p> <p>The distinguished editors have included practical and accessible resources that address the biological and delivery approaches to pulmonary and mucosal delivery of drugs. Emergency care settings are also described, with explorations of the relationship between parenteral infusion profiles and PK/PD. The future of drug delivery is addressed via discussions of virtual experiments to elucidate mechanisms and approaches to drug delivery and personalized medicine.</p> <p>Readers will also benefit from the inclusion of:</p> <ul> <li>A thorough introduction to the utility of mathematical models in drug development and delivery</li> <li>An exploration of the techniques and applications of physiologically based models to drug delivery</li> <li>Discussions of oral delivery and pharmacokinetic models and oral site-directed delivery</li> <li>A review of integrated transdermal delivery and pharmacokinetics in development</li> <li>An examination of virtual experiment methods for integrating pharmacokinetic, pharmacodynamic, and drug delivery mechanisms</li> <li>Alternative endpoints to pharmacokinetics for topical delivery</li> </ul> <p>Perfect for researchers, industrial scientists, graduate students, and postdoctoral students in the area of pharmaceutical science and engineering, <em>Drug Delivery Approaches: Perspectives from Pharmacokinetics and Pharmacodynamics</em> will also earn a place in the libraries of formulators, pharmacokineticists, and clinical pharmacologists.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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27,324円
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Putting Pharmacokinetics and Pharmacodynamics to Work in Drug Discovery A Practical Guide for Pharmaceutical Scientists【電子書籍】[ Emile P. Chen ]
楽天Kobo電子書籍ストア
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<p><strong>Develop drugs with a greater understanding of their physiological effects</strong></p> <p>Pharmaceutical scientists in the fields of pharmacokinetics and pharmacodynamics study how drugs behave in the body and how they reach their site of action to exert their intended pharmacological activities. Drug discovery stands to benefit enormously from the timely application of pharmacokinetics and pharmacodynamics in order to make informed decisions and solve practical problems.</p> <p><em>Putting Pharmacokinetics and Pharmacodynamics to Work in Drug Discovery</em> bridges between scientific concepts and practical industrial practice by bringing these principles to bear on every stage of the drug discovery process. Beginning with target identification and moving through each subsequent decision point including high throughput screening, hit-to-lead, lead optimization and candidate selection. The book offers a comprehensive guide to using various analytical tools including modeling and AI/ML for minimizing attrition, reducing costs, and more. The result is an invaluable tool in developing smarter and more effective drug discovery processes.</p> <p><em>Putting Pharmacokinetics and Pharmacodynamics to Work in Drug Discovery</em> readers will also find:</p> <ul> <li>A work designed to make scientific principles accessible to pharmaceutical scientists in diverse areas, not just pharmacokinetists or DMPK scientists</li> <li>Industrial examples, both positive and negative, showing pharmacokinetic and pharmacodynamic principles at work</li> <li>Exercises throughout the book to encourage holistic and integrated thinking</li> </ul> <p><em>Putting Pharmacokinetics and Pharmacodynamics to Work in Drug Discovery</em> is ideal for any researchers or professionals involved in drug discovery and development, including medicinal chemists, biopharmaceutics scientists, clinicians, project leaders, and many others.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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20,232円
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New Horizons in Predictive Drug Metabolism and Pharmacokinetics【電子書籍】
楽天Kobo電子書籍ストア
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<p>Drug metabolism, pharmacokinetics and toxicokinetics as determinants of drug attrition and the safety of xenobiotics are critically important. This book presents a comprehensive treatise on the current issues and challenges facing drug metabolism and pharmacokinetics. Readers will find a thorough exploration of their predictive role in impacting drug discovery and development and in improving the success rate and safety assessment of pharmaceuticals and industrial or occupational chemicals. Chapters not only focus on the current state of art, with distinct examples, but on future needs and approaches likely to improve our prediction of potential human risk.<br /> Discussions of critical properties that are determinants of a compound’s metabolic and pharmacokinetic fate follow introductory chapters. The Drug Discovery process increasingly incorporates pharmacokinetics and drug metabolism screening and focus has shifted towards in silico, computational and systems biology approaches. Core chapters reflect this and the recent interest and need to assess the role of transporters, along with drug metabolizing enzymes, as potential determinants of pharmacokinetic behaviour, toxicity and drug-drug interactions. Lastly, chapters cover the issues and factors involved in translating pharmacokinetics from in silico to in vivo and from animal models to man, and postulate future directions and opportunities.<br /> Leading experts from academia, industry and regulatory bodies across the globe contribute their knowledge to this book, which scientists involved in many aspects of the drug discovery process, as well as regulators and postgraduate students, will find a useful resource.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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33,575円
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洋書 Springer Paperback, "Handbook of Essential Pharmacokinetics, Pharmacodynamics and Drug Metabolism for Industrial Scientists"
Glomarket
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*** We ship internationally, so do not use a package forwarding service. We cannot ship to a package forwarding company address because of the Japanese customs regulation. If it is shipped and customs office does not let the package go, we do not make a refund. 【注意事項】 *** 特に注意してください。 *** ・個人ではない法人・団体名義での購入はできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 ・お名前にカタカナが入っている場合法人である可能性が高いため当店システムから自動保留します。カタカナで記載が必要な場合はカタカナ変わりローマ字で記載してください。 ・お名前またはご住所が法人・団体名義(XX株式会社等)、商店名などを含めている場合、または電話番号が個人のものではない場合、税関から法人名義でみなされますのでご注意ください。 ・転送サービス会社への発送もできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 *** ・注文後品切れや価格変動でキャンセルされる場合がございますので予めご了承願います。 ・当店でご購入された商品は、原則として、「個人輸入」としての取り扱いになり、すべてニュージャージからお客様のもとへ直送されます。 ・ご注文後、30営業日以内(通常2~3週間)に配送手続きをいたします。配送作業完了後、2週間程度でのお届けとなります。 ・まれに商品入荷状況や国際情勢、運送、通関事情により、お届けが2ヶ月までかかる場合がありますのでお急ぎの場合は注文をお控えください。 ・個人輸入される商品は、すべてご注文者自身の「個人使用・個人消費」が前提となりますので、ご注文された商品を第三者へ譲渡・転売することは法律で禁止されております。 ・関税・消費税が課税される場合があります。詳細はこちらをご確認下さい。PC販売説明文
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32,922円
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200 MCQs in Clinical Pharmacokinetics【電子書籍】[ Hamza Alhamad ]
楽天Kobo電子書籍ストア
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<p>This book contains 200 comprehensive multiple-choice questions in clinical pharmacokinetics, aiding pharmacy students and healthcare professionals in assessing their understanding of key concepts and principles in the field.</p> <p>Pharmacokinetics is the branch of pharmacology concerned with studying how the body interacts with the administered drugs for the entire duration of exposure, including absorption, distribution, metabolism, and elimination (ADME). Clinical pharmacokinetics is the science that describes the absorption, distribution, metabolism, and elimination of drugs in patients requiring drug therapy. Clinical pharmacokinetics is concerned with applying pharmacokinetic principles to the safe and effective therapeutic management of drugs in individual patients.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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1,550円
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Pharmacology & Pharmacokinetics A Basic Reader【電子書籍】
楽天Kobo電子書籍ストア
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<p>Effective drug administration is a crucial skill for any practitioner working in the critical care unit. This book, in providing a concise account of the fundamental principles of pharmacology and pharmacokinetics, equips the critical care physician for such a task. In addition to the principles of pharmacology and pharmacokinetics, this volume alerts the reader to factors that affect drug action such as disease, pregnancy and age, and advises on how to adjust drug dosages accordingly. The specialist therapeutics covered comprise drugs targeting the gastro-intestinal tract, sedation, non-opioid analgesia and opiates. A quick and easy reference, this volume will prove a valuable asset for both trainees and fully qualified practitioners in critical care.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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7,900円
|

Mass Spectrometry in Drug Metabolism and Pharmacokinetics【電子書籍】
楽天Kobo電子書籍ストア
|
<p>This timely reference discusses mass spectrometry in drug metabolism and pharmacokinetic studies. With contributions by professionals from the pharmaceutical industry, this book begins with a review of current mass spectrometry techniques and applications, followed by discussions of various methods for using MS in drug metabolism studies and pharmacokinetics. Highlighting the critical importance of ADME studies for understanding how a drug is absorbed, distributed, metabolized, and excreted by the body, the book s focuses on the use of LC/MS and MALDI-MS. This is a valuable reference for scientists in the pharmaceutical industry, medicine, academia, and even those working in homeland defense.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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18,226円
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洋書 Pharmaceutical Press Paperback, Basic Pharmacokinetics
Glomarket
|
*** We ship internationally, so do not use a package forwarding service. We cannot ship to a package forwarding company address because of the Japanese customs regulation. If it is shipped and customs office does not let the package go, we do not make a refund. 【注意事項】 *** 特に注意してください。 *** ・個人ではない法人・団体名義での購入はできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 ・お名前にカタカナが入っている場合法人である可能性が高いため当店システムから自動保留します。カタカナで記載が必要な場合はカタカナ変わりローマ字で記載してください。 ・お名前またはご住所が法人・団体名義(XX株式会社等)、商店名などを含めている場合、または電話番号が個人のものではない場合、税関から法人名義でみなされますのでご注意ください。 ・転送サービス会社への発送もできません。この場合税関で滅却されてもお客様負担になりますので御了承願います。 *** ・注文後品切れや価格変動でキャンセルされる場合がございますので予めご了承願います。 ・当店でご購入された商品は、原則として、「個人輸入」としての取り扱いになり、すべてニュージャージからお客様のもとへ直送されます。 ・ご注文後、30営業日以内(通常2~3週間)に配送手続きをいたします。配送作業完了後、2週間程度でのお届けとなります。 ・まれに商品入荷状況や国際情勢、運送、通関事情により、お届けが2ヶ月までかかる場合がありますのでお急ぎの場合は注文をお控えください。 ・個人輸入される商品は、すべてご注文者自身の「個人使用・個人消費」が前提となりますので、ご注文された商品を第三者へ譲渡・転売することは法律で禁止されております。 ・関税・消費税が課税される場合があります。詳細はこちらをご確認下さい。PC販売説明文
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24,743円
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Pharmacokinetics: Basics to Applications PHARMACOKINETICS BASICS TO APP [ Biswajit Mukherjee ]
楽天ブックス
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PHARMACOKINETICS BASICS TO APP Biswajit Mukherjee SPRINGER NATURE2022 Hardcover 2022 English ISBN:9789811689499 洋書 Computers & Science(コンピューター&科学) Medical
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32,736円
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A Short Guide to Clinical Pharmacokinetics【電子書籍】
楽天Kobo電子書籍ストア
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<p>This book is a complete resource on pharmacokinetics, pharmacodynamics and pharmacogenomics in clinical practice. It consists of seven chapters that cover various aspects of pharmacokinetics and its clinical applications. The chapters are structured to provide clear objectives and keywords are bolded throughout the text to facilitate understanding. The topics covered include the significance of pharmacokinetics in clinical practice, factors affecting pharmacokinetic parameters, pharmacokinetic drug interactions, therapeutic drug monitoring, dosage adjustment in different population groups, the influence of hepatic diseases on pharmacokinetics and the impact of pharmacogenomics on pharmacokinetics and pharmacodynamics. The book is written in simple language to make the concepts accessible to all readers. This book is a comprehensive resource for students pursuing a doctoral degree in pharmacy, as well as academicians and researchers in clinical pharmacokinetics.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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20,662円
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Handbook of Pharmacokinetics and Toxicokinetics【電子書籍】[ Mehdi Boroujerdi ]
楽天Kobo電子書籍ストア
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<p>This fully revised and expanded volume is an effort to blend the common approaches to pharmacokinetics and toxicokinetics. It integrates the principles held in common by both fields through a logical and systematic approach, which includes mathematical descriptions of physical and physiological processes employed in the approaches to pharmacokinetics and toxicokinetics modeling. It emphasizes general principles and concepts and related, isolated applications and case study observations. The systematic compilation of mathematical concepts and methodologies allows readers to decide on relevant concepts and approaches for their research, scientific or regulatory decisions, or for offering advanced courses/workshops and seminars.</p> <p>Features:</p> <ul> <li>Comprehensive handbook on principles and applications of PK/TK appealing to a diverse audience including scientists and students</li> <li>An excellent text fully revised and fully updated for anyone interested in the theoretical and practical pharmacokinetics</li> <li>The systematic compilation of mathematical concepts and methodologies allows readers to decide on relevant concepts and approaches for their research</li> <li>Incorporates research relevant to SDGs and of interest to industrial and regulatory environmental scientists involved in chemical contamination research and regulatory decision making related to soil, water, and ocean</li> <li>Includes sections on applications and case studies</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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9,188円
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Introduction to Drug Disposition and Pharmacokinetics【電子書籍】[ Stephen H. Curry ]
楽天Kobo電子書籍ストア
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<p>The application of knowledge of drug disposition, and skills in pharmacokinetics, are crucial to the development of new drugs and to a better understanding of how to achieve maximum benefit from existing ones. The book takes the reader from basic concepts to a point where those who wish to will be able to perform pharmacokinetic calculations and be ready to read more advanced texts and research papers.</p> <p>The book will be of benefit to students of medicine, pharmacy, pharmacology, biomedical sciences and veterinary science, including those who have elected to study the topic in more detail, such as via electives and special study modules. It will be of benefit to those involved in drug discovery and development, pharmaceutical and medicinal chemists, as well as budding toxicologists and forensic scientists who require the appropriate knowledge to interpret their findings and as an introductory text for clinical pharmacologists. Early chapters describe the basic principles of the topic while the later ones illustrate the application of those principles to modern approaches to drug development and clinical use. Full colour illustrations facilitate the learning experience and supporting material for course leaders and students can be found on the Companion Web Site</p> <p>"Another book on PK? Yes and there should be and it should be <em>DD & PK.</em> It is good, unique, and does fill a currently unmet need for those working in the xenobiotic arena. <em>DD & PK</em> is just like the perfect mystery novelーthe one “you just can’t put down.” However, unlike a mystery novel which requires only one reading to find the answer, the reader of <em>DD & PK</em> will learn more than an answer to a single question. The reader will find many solutions to a wide variety of mysterious problems associated with the time course and actions of xenobiotics."<br /> ***ー*<em><em><em>International Journal of Toxicology</em>, John A. Budny, PhD</em>,</em> President, PharmaCal, Ltd, 2018</p> <p>"This book has many innovations that make a welcome addition to the bookshelves of a wide range of pharmaceutical scientists. The effective use of ?gures and tables to summarize and clarify a wide range of issues is to be commended, as are the learning objectives at the start of the chapter coupled with the summary at the end providing a succinct way in understanding the objectives of the chapter and together with links to a website provides accessibility for all from the neophyte pharmacokineticist to the consultant physician. A book all in the Pharma industry should be aware of.*"<br /> **ー*<em>Int. J. of Pharmacokinetics,</em> Howard M. Hill, ResolvPharma, 2018</p> <p>"Overall, Introduction to Drug Disposition and Pharmacokinetics o?ers its readership an in-depth view of classic pharmacokinetic concepts. This book would be an excellent choice for a pharmacokinetics elective or as an adjunctive text for an introductory course. This book reviews a wide array of clinically relevant topics and encourages the reader to apply the knowledge gained to all medi-cations. A robust and varied amount of online material is provided to enhance understanding and encourage discussion. It is likely that all readers, novice or experienced pharmacists, would ?nd value in this textbook."<br /> <em>ー Currents in Pharmacy Teaching and Learning,</em> Milena McLaughlin, Midwestern University Chicago College of Pharmacy, 2018</p> <p>"In summary, this is an excellent textbook for students new to the field of pharmaceutics and medical, pharmacy, and veterinary students, particularly those who envision a career in drug development research in either academia or industry."<br /> ー<em>Veterinary Pathology Review</em>, John K. Amory, University of Washington, 2018</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。
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11,094円
|
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