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Developmental Human Behavioral Epigenetics Principles, Methods, Evidence, and Future Directions【電子書籍】[ Trygve Tollefsbol ]

楽天Kobo電子書籍ストア
<p><em>Developmental Human Behavioral Epigenetics: Principles, Methods, Evidence, and Future Directions, Volume 23</em>, a new volume in the Translational Epigenetics series, offers the first systematic account of theoretical G79 frameworks, methodological approaches, findings, and future directions in the field of human behavioral epigenetics. Featuring contributions from leading scientists and international researchers, this book provides a comprehensive overview of human behavioral epigenetics, with a close examination of evidence gathered to-date from animal models, challenges of human-based research and clinical translation, pathways towards drug discovery, and next steps in research.</p> <p>Areas of focus include prenatal stress exposures, preterm behavioral epigenetics, intergenerational exposures, trauma and neglect, socio-economic conditions, maternal caregiving and attachment, study design, and epigenetics and psychotherapy.</p> <ul> <li>Enables more effective study design and methods application in behavioral epigenetics research across human and animal models</li> <li>Examines findings in human behavioral epigenetics to-date</li> <li>Features contributions from leading international researchers in behavioral epigenetics</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 14,830円

Cancer and Noncoding RNAs【電子書籍】[ Trygve Tollefsbol ]

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<p><em>Cancer and Noncoding RNAs</em> offers an in-depth exploration of noncoding RNAs and their role in epigenetic regulation of complex human disease, most notably cancer. In addition to examining microRNAs, this volume provides a unique evaluation of more recently profiled noncoding RNAs now implicated in carcinogenesis, including lncRNAs, piRNAs, circRNAs, and tRNAs, identifying differences in function between these noncoding RNAs and how they interact with the rest of the epigenome. A broad range of chapters from experts in the field detail epigenetic regulation of various cancer types, along with recent next generation sequencing technologies, genome-wide association studies (GWAS) and bioinformatics approaches.</p> <p>This book will help researchers in genomic medicine and cancer biology better understand the role of noncoding RNAs in epigenetics, aiding in the development of useful biomarkers for diagnosis, prognosis and new RNA-based disease therapies.</p> <ul> <li>Provides a comprehensive analysis of noncoding RNAs implicated in epigenetic regulation of gene expression and chromatin dynamics</li> <li>Educates researchers and graduate students by highlighting, in addition to miRNAs, a range of noncoding RNAs newly associated with carcinogenesis</li> <li>Applies current knowledge of noncoding RNAs and epigenomics towards developing cancer and RNA-based disease therapies</li> <li>Features contributions by leading experts in the field</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 19,773円

The Preacher as Liturgical Artist Metaphor, Identity, and the Vicarious Humanity of Christ【電子書籍】[ Trygve David Johnson ]

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<p>Trygve Johnson invites us to consider a new metaphor of identity of The Preacher as Liturgical Artist. This identity draws on a theology of communion and the doctrine of the vicarious humanity of Christ to relocate the preacher's identity in the creative and ongoing ministry of Jesus Christ. Johnson argues the metaphorical association of the preacher and artist understood within the artistic ministry of Jesus Christ frees the full range of human capacities, including the imagination to bear upon the arts of Christian proclamation. The Preacher as Liturgical Artist connects preachers to the person and work of Jesus Christ, whose own double ministry took the raw materials of the human condition and offered them back to the Father in a redemptive and imaginative fashion through the Holy Spirit. It is in the large creative ministry of Jesus Christ that preachers find their creativity freed to proclaim the gospel bodily within the context of the liturgical work of God's people.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 2,884円

In the Beginning Secretary-General Trygve Lie and the Establishment of the United Nations【電子書籍】[ Ellen J. Ravndal ]

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<p>This book reviews the formative years of the United Nations (UN) under its first Secretary-General Trygve Lie. This welcome appraisal shows how the foundations for an expanded secretary-general role were laid during this period, and that Lie’s contribution was greater than has later been acknowledged. The interplay of crisis decision-making, institutional constraints and the individuals involved thus built the foundations for the UN organization we know today. Addressing important wider questions of IGO creation, governance and autonomy, this is an incisive account of how the UN moved from paper to practice under Lie.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 3,863円

Chromatin Readers in Health and Disease【電子書籍】[ Trygve O Tollefsbol ]

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<p><em>Chromatin Readers in Health and Disease, Volume 35,</em> a new release in the Translational Epigenetics series, gathers and makes actionable our current understanding of how chromatin readers regulate access to genetic information, and how their aberrant regulation can contribute to human pathologies. Chromatin readers discussed include 14-3-3 Dinshaw, ADD, Ankyrin, BAH, BET, BIR, BRCT, bromodomains and Kac readers, chromodomains and chromobarrel readers, citrullination readers, macrodomains and poly-ADP-ribose readers, MBT, PHD and double PHD, PWWP, SUMO (H4K12) readers, Tudor and TTD, UDR and ubiquitin, WD40, YEATS (crotonyl reader), MBD, SRA, and Methyl-RNA readers.In the book, more than a dozen leaders in the field examine a range of protein readers, their relationship to human disease, and the early therapeutics that act as chromatin signaling factors to treat cancers and Huntington's disease, among other disorders.</p> <ul> <li>Enables researchers and clinicians to understand chromatin signaling mechanisms that regulate gene expression through chromatin readers</li> <li>Highlights the role of chromatin readers in a variety of human pathologies, as well as early therapeutics that act on chromatin signaling</li> <li>Includes chapter contributions from international leaders in the field</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 17,301円

Epigenetics and Metabolomics【電子書籍】[ Trygve Tollefsbol ]

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<p><em>Epigenetics and Metabolomics</em>, a new volume in the Translational Epigenetics series, offers a synthesized discussion of epigenetic control of metabolic activity, and systems-based approaches for better understanding these mechanisms. Over a dozen chapter authors provide an overview of epigenetics in translational medicine and metabolomics techniques, followed by analyses of epigenetic and metabolomic linkage mechanisms likely to result in effective identification of disease biomarkers, as well as new therapies targeting the removal of the inappropriate epigenetic alterations. Epigenetic interventions in cancer, brain damage, and neuroendocrine disease, among other disorders, are discussed in-depth, with an emphasis on exploring next steps for clinical translation and personalized healthcare.</p> <ul> <li>Offers a synthesized discussion of epigenetic regulation of metabolic activity and systems-based approaches to power new research</li> <li>Discusses epigenetic control of metabolic pathways and possible therapeutic targets for cancer, neurodegenerative, and neuroendocrine diseases, among others</li> <li>Provides guidance in epigenomics and metabolomic research methodology</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 17,301円

Mathematical Theory of Compressible Viscous Fluids Analysis and Numerics【電子書籍】[ Trygve G. Karper ]

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<p>This book offers an essential introduction to the mathematical theory of compressible viscous fluids. The main goal is to present analytical methods from the perspective of their numerical applications. Accordingly, we introduce the principal theoretical tools needed to handle well-posedness of the underlying Navier-Stokes system, study the problems of sequential stability, and, lastly, construct solutions by means of an implicit numerical scheme. Offering a unique contribution ? by exploring in detail the “synergy” of analytical and numerical methods ? the book offers a valuable resource for graduate students in mathematics and researchers working in mathematical fluid mechanics.</p> <p>Mathematical fluid mechanics concerns problems that are closely connected to real-world applications and is also an important part of the theory of partial differential equations and numerical analysis in general. This book highlights the fact that numerical and mathematical analysis are not two separate fields of mathematics. It will help graduate students and researchers to not only better understand problems in mathematical compressible fluid mechanics but also to learn something from the field of mathematical and numerical analysis and to see the connections between the two worlds. Potential readers should possess a good command of the basic tools of functional analysis and partial differential equations including the function spaces of Sobolev type.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 12,154円

Twin and Family Studies of Epigenetics【電子書籍】[ Trygve O Tollefsbol ]

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<p><em>Twin and Family Studies of Epigenetics, Volume 27</em>, the latest release in the Translational Epigenetics series, gathers expert opinions on epigenetic twin and family study research methods, recent findings across various disease areas, and future directions. The book provides in-depth coverage of epigenetics fundamentals, twin and family epigenetic study design, and the broader role of epigenetics in answering questions on the developmental origins of health and disease. Throughout the volume, twin and family studies are employed to examine causes of epigenetic variation, the relationship between epigenetic modifications and mental illness, cancers, cardiovascular disease, diabetes, obesity, high blood pressure, and more.</p> <p>Emerging research methods applied in twin and family studies discussed include imaging epigenetics, exposure-specific DNA methylation changes, and unravelling time trends in epigenetic effects.</p> <ul> <li>Offers a practical, interdisciplinary approach across epigenetics, epidemiology and various disease specialties</li> <li>Applies epigenetic twin and family studies to determine the relationship between epigenetics and mental illness, cancers, cardiovascular disease, diabetes, obesity and high blood pressure, among other diseases and disorders</li> <li>Features chapter contributions from a wide range of international researchers in the field</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 17,301円

Environmental Epigenetics in Toxicology and Public Health【電子書籍】[ Trygve O Tollefsbol ]

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<p><em>Environmental Epigenetics in Toxicology and Public Health</em> provides in-depth discussions of the suite of complex environmental factors shown to impact epigenetic components within the cell, as well as evidence that these epigenetic modifications are tied to early and later life health effects. This book offers a translational research perspective, highlighting both in vivo and human population-based evidence for ties between the environment, the epigenome, and health outcomes, with an emphasis on evidence for transgenerational effects of exposures, as well as developmental windows of susceptibility to environmentally-linked epigenetic effects.</p> <p>This volume in the Translational Epigenetics series aides in the development of new therapeutic options meant to reverse inappropriate epigenetic alterations, helping researchers in their efforts prevent and treat a variety of chronic diseases tied to environmental exposures.</p> <ul> <li>Offers a thorough discussion of the environmental factors influencing epigenetic mechanisms in early and late life, and in transgenerational inheritance</li> <li>Examines both animal model and human population-based research in environmental epigenetics, highlighting developmental windows of vulnerability to epigenetic modification</li> <li>Features contributions from international experts in the field</li> </ul>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 18,290円

Policy Learning from Canada Reforming Scandinavian Immigration and Integration Policies【電子書籍】[ Trygve Ugland ]

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<p>Focusing on the three Scandinavian countries, Denmark, Norway, and Sweden, <em>Policy Learning from Canada</em> is a systematic study of the international relevance of the Canadian immigration and integration policy model. To reveal how the Canadian immigration model has shaped the reform process in Scandinavia, Trygve Ugland critically examines public documents, including government proposals, documents from parliamentary debates, and reports by ad-hoc expert commissions, as well as letters from consulted agencies.</p> <p>Ugland’s intensive studies on Canada’s immigration and integration policies depict Canada not only as a model and inspiration to Scandinavian policy makers, but, in particular, as an intellectual stimulus for the rediscovery of labour immigration in Scandinavia during the 2000s. The study demonstrates that the Canadian model, often perceived as a product of unique circumstances, can be relevant in other countries.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 5,768円

A Performative Feel for the Game How Meaningful Sports Shape Gender, Bodies, and Social Life【電子書籍】[ Trygve B. Broch ]

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<p>Applying a cultural sociology of performance, this book interrogates how the meaning of sport intersects with gender. Trygve B. Broch points out uncertainties in the causal arguments made by key figures in the cultural studies tradition, instead advancing a meaning-centered study of sports as involving both a social and an athletic performance. Sports not only reflect or reverse social realities, but capture and keep our attention when we use and experience them as a means to reflect on social life, injustice, and hierarchy. More specifically, blending approaches from media studies with ethnography, Broch explores the women-dominated sport of handball in Norway, a country that considers gender equality a basis of democracy. As such, the analyses here show how broadly available meanings about sameness and equality are mediated and experienced through <em>a performative feel for the game</em>.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 10,938円

Jean Monnet and Canada Early Travels and the Idea of European Unity【電子書籍】[ Trygve Ugland ]

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<p>Jean Monnet (1888-1979) is often viewed as the chief architect of the European Coal and Steel Community, which over time evolved into today's European Union. Monnet spent his early years working as an agent for his father, a cognac producer. It was this experience that took him to Scandinavia, England, the United States, and most importantly Canada, where he was exposed to the country's unique form of federalism.</p> <p>Drawing on a wide variety of empirical sources, including unpublished documents, correspondence, and original historical data extracted from archives both in Canada and Europe, Trygve Ugland's <em>Jean Monnet and Canada</em> argues that the extensive period of time Monnet spent in Canada between 1907 and 1914 had a formative influence on the achievements of his later years, particularly on the institutional 'construction of Europe.'</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 4,803円

Power without Victory Woodrow Wilson and the American Internationalist Experiment【電子書籍】[ Trygve Throntveit ]

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<p>For decades, Woodrow Wilson has been remembered as either a paternalistic liberal or reactionary conservative at home and as a na?ve idealist or cynical imperialist abroad. Historians’ harsh judgments of Wilson are understandable. He won two elections by promising a deliberative democratic process that would ensure justice and political empowerment for all. Yet under Wilson, Jim Crow persisted, interventions in Latin America increased, and a humiliating peace settlement was forced upon Germany. A generation after Wilson, stark inequalities and injustices still plagued the nation, myopic nationalism hindered its responsible engagement in world affairs, and a second vastly destructive global conflict threatened the survival of democracy worldwideーleaving some Americans today to wonder what, exactly, the buildings and programs bearing his name are commemorating.</p> <p>In <em>Power without Victory</em>, Trygve Throntveit argues that there is more to the story of Wilson than these sad truths. Throntveit makes the case that Wilson was not a “Wilsonian,” as that term has come to be understood, but a principled pragmatist in the tradition of William James. He did not seek to stamp American-style democracy on other peoples, but to enable the gradual development of a genuinely global system of governance that would maintain justice and facilitate peaceful changeーa goal that, contrary to historical tradition, the American people embraced. In this brilliant intellectual, cultural, and political history, Throntveit gives us a new vision of Wilson, as well as a model of how to think about the complex relationship between the world of ideas and the worlds of policy and diplomacy.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 4,059円

First People History I stood here first, and Columbus first discovered me! Chitto Harjo【電子書籍】[ Trygve T Jorgensen ]

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<p>The 2nd edition is focused solely on the 39 tribes of Oklahoma. This book satisfies 70 O.S. § 11-103.6b (OSCN 2022) Diversity of Social Studies Core Curriculum</p> <p>A. The State Board of Education shall adopt a social studies core curriculum with courses of instruction for all students enrolled in the public schools that reflect the racial, ethnic, religious, and cultural diversity of the United States of America. The United States history and Oklahoma history components required in the social studies curriculum for all students shall include, but not be limited to, African Americans, Native Americans, and Hispanic Americans.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 5,675円

William James and the Quest for an Ethical Republic【電子書籍】[ Trygve Throntveit ]

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<p>Pragmatist philosopher William James has long been deemed a dubious guide to ethical reasoning. This book overturns such thinking, demonstrating the coherence of James's efforts to develop a flexible but rigorous framework for individuals and societies seeking freedom, meaning, and justice in a world of interdependence, uncertainty, and change.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 6,076円

Working Class Radicalism in Mid-Victorian England【電子書籍】[ Trygve Tholfsen ]

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<p>Originally published in 1976, <em>Working Class Radicalism in Mid-Victorian England</em> examines working-class radicalism in the mid-Victorian period and suggests that after the fading of Chartist militancy the radical tradition was preserved in a working-class subculture that enabled working men to resist the full consolidation of middle-class hegemony. The book traces the growth of working-class radicalism as it developed dialectically in confrontation with middle-class liberal ideology in the generation after Waterloo. Intellectual forces were of central importance in shaping the character of the working-class Left and the Enlightenment, in particular, as the chief source of ideological weapons that were turned against the established order. The Enlightenment also provided the intellectual foundations of the middle-class ideology that was directed against the incipient threat of popular radicalism. The book notes that the same intellectual forces that entered into the first half of the nineteenth century also shaped the value system that provided the foundations of mid-Victorian urban culture. These forces also contributed to the rapprochement between working-class liberalism, bringing latent affinities to the surface. It is also emphasised, however, that inherited ideas and traditions exercised their influence in interaction with the structure of power and status.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 6,542円

Elites in an Egalitarian Society Support for the Nordic Model【電子書籍】[ Trygve Gulbrandsen ]

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<p>Based on two unique survey studies of elites in Norway, this book examines whether elite attitudes towards central national issues have changed in the wake of international and national events and developments since 2000. The chapters examine elite integration and relations between elites and citizens in Norway as a means to discuss the continued viability of the Nordic welfare state model. This insight into how elites relate to central issues in Norwegian society and how they look upon citizens’ political interest and competence in general, will be of interest to academics within sociology and political science, as well as journalists and commentators and policy makers.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 6,076円

UND EWIG SINGEN DIE W?LDER Erster Roman der BJ?RNDAL-Trilogie【電子書籍】[ Trygve Gulbranssen ]

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<p>Die reichen Bauern Bj?rndal und die benachbarte Adelsfamilie von Gall sind tief verfeindet. Als Tore, der Sohn des alten Bj?rndal, bei einem Duell um die Nachbarstochter stirbt, beschw?rt der unvers?hnliche Hass des Alten eine Trag?die herauf...</p> <p>Der Roman <em>Und ewig singen die W?lder</em> des norwegischen Schriftstellers Trygve Gulbranssen (* 15. Juni 1894 in Kristiania; † 10. Oktober 1962 in Eidsberg) erschien erstmals im Jahr 1935 und gilt als einer der gro?en Klassiker des Heimatromans.</p> <p>1959 wurde der Roman unter der Regie von Paul May ?beraus erfolgreich verfilmt. In den Hauptrollen: Gert Fr?be (als der alte Dag), Hansj?rg Felmy (als Tore), Joachim Hansen (als der junge Dag), Anna Smolik (als Elisabeth von Gall), Hans Nielsen (als Oberst a. D. Barre), Maj-Britt Nilsson (als Adelheid Barre) und Carl Lange als (Oberst a. D. von Gall).</p> <p>Der Apex-Verlag ver?ffentlicht eine durchgesehene Neuausgabe der <em>Bj?rndal</em>-Trilogie.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 970円

DAS ERBE VON BJ?RNDAL Zweiter Roman der BJ?RNDAL-Trilogie【電子書籍】[ Trygve Gulbranssen ]

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<p>Der Roman <em>Das Erbe von Bj?rndal</em> des norwegischen Schriftstellers Trygve Gulbranssen (* 15. Juni 1894 in Kristiania; † 10. Oktober 1962 in Eidsberg) erschien erstmals im Jahr 1934 und gilt - wie auch sein Vorg?nger <em>Und ewig singen die W?lder</em> - als einer der gro?en Klassiker des Heimatromans.</p> <p>1960 wurde der Roman unter der Regie von Gustav Ucicky ?beraus erfolgreich (und recht frei) verfilmt. In den Hauptrollen: Joachim Hansen (als Dag), Maj-Britt Nilsson (als Adelheid Barre), Brigitte Horney (als Tante Eleonore), Hans Nielsen (Oberst a. D. Barre), Ellen Schwiers (als Gunvor) und Carl Lange als (Oberst a. D. von Gall).</p> <p>Der Apex-Verlag ver?ffentlicht eine durchgesehene Neuausgabe der <em>Bj?rndal</em>-Trilogie.</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 1,091円

A Free Spirited Life Coming of Age While America Waged War on Vietnam【電子書籍】[ Trygve Sletteland ]

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<p>This is the colorful story of the life and times of an early Baby Boom generation member. In the US anyway, "Boomers" tended to be individualistic, experimental and social cause-oriented. They epitomized the cultural change of the 1960's. Memorable events of this time included the Cold War, "Red Scare", Cuban Missile Crisis, assassinations of JFK, RFK and MLK, Jr., political unrest, first moon walk, risk of the draft or military service in Vietnam, anti-war protests, women's liberation, "free love," the Civil Rights and Environmental Movements, drug experimentation, protests and riots, and Woodstock. The author was a "free spirit" and stand-out member of a very large generation. It was an exciting time - and a time to stand up and make a difference!</p>画面が切り替わりますので、しばらくお待ち下さい。 ※ご購入は、楽天kobo商品ページからお願いします。※切り替わらない場合は、こちら をクリックして下さい。 ※このページからは注文できません。 667円